Wilate

Generic Name: antihemophilic factor/von willebrand factor (AN-tye-HEE-moe-FIL-ik FAK-tor/von WILL-a-brand FAK-tor)
Brand Name: Wilate

Wilate is used for:

Treating bleeding episodes in certain patients with von Willebrand disease.

Wilate is a human clotting factor complex prepared from pooled human plasma. It works by increasing the amount of clotting factor VIII and von Willebrand factor in the blood. This helps the blood to clot properly, which helps to stop bleeding.

Do NOT use Wilate if:

  • you are allergic to any ingredient in Wilate (including polysorbate 80) or in the container
  • you have had a severe allergic reaction (eg, rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue) to other medicines that contain antihemophilic factor or von Willebrand factor or other medicines made from human plasma

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Wilate:

Some medical conditions may interact with Wilate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood clots in the legs, lungs, or eye, or if you are at risk for developing blood clots
  • if you have hemophilia A

Some MEDICINES MAY INTERACT with Wilate. However, no specific interactions with Wilate are known at this time.

Ask your health care provider if Wilate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Wilate:

Use Wilate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Wilate is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Wilate at home, a health care provider will teach you how to use it. Be sure you understand how to use Wilate. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not shake Wilate. Gently swirl to mix.
  • Wilate should be colorless to slightly yellow in appearance after it has been mixed. Do not use Wilate if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Use Wilate immediately after mixing. Discard any remaining solution after use.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Wilate, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Wilate.

Important safety information:

  • Wilate may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Wilate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Patients receiving clotting factors sometimes develop antibodies or inhibitors to the medicine. This makes it less effective. If Wilate stops working or does not work as well as it has before, contact your doctor immediately for instructions.
  • Wilate is made from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products made from human blood. Discuss any questions or concerns with your doctor. Discuss whether you should receive a hepatitis A and hepatitis B vaccine.
  • Tell your doctor or dentist that you take Wilate before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including factor VIII levels and von Willebrand factor levels, may be performed while you use Wilate. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: It is not known if Wilate can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Wilate while you are pregnant. It is not known if Wilate is found in breast milk. If you are or will be breast-feeding while you use Wilate, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Wilate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; mild itching at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); burning or stinging at the injection site; calf or leg pain, redness, swelling, or tenderness; chest pain; coughing up blood; fainting; fast heartbeat; fever or chills; flushing; nausea; new or worsening bruising or bleeding; restlessness; severe or persistent dizziness or headache; shortness of breath; sluggishness; tingling; unusual weakness or fatigue; vomiting; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Wilate:

Store Wilate in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Do not use past the expiration date on the container. Wilate also may be stored at room temperature, below 77 degrees F (25 degrees C), for up to 6 months or until the expiration date, whichever occurs first. Store away from heat and light. Do not return Wilate to the refrigerator once it has been stored at room temperature. Keep Wilate out of the reach of children and away from pets.

General information:

  • If you have any questions about Wilate, please talk with your doctor, pharmacist, or other health care provider.
  • Wilate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Wilate or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Wilate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Wilate. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Wilate.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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