Medication Guide App

Valrubicin

Generic Name: valrubicin (val-ROO-bi-sin)
Brand Name: Valstar

Valrubicin is used for:

Treating certain types of bladder cancer in certain patients.

Valrubicin is an anthracycline cytotoxic agent. It works by preventing the cancer cell from reproducing, which results in death of the cancer cell.

Do NOT use valrubicin if:

  • you are allergic to any ingredient in valrubicin (including polyoxyl castor oil) or to other anthracycline medicines (eg, daunorubicin)
  • you have a urinary tract infection, a hole in your bladder (eg, perforation or rupture), or problems with the lining of your bladder

Contact your doctor or health care provider right away if any of these apply to you.

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Before using valrubicin:

Some medical conditions may interact with valrubicin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have bone marrow problems, kidney problems, or severe irritable bladder

Some MEDICINES MAY INTERACT with valrubicin. Because little, if any, of valrubicin is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if valrubicin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use valrubicin:

Use valrubicin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Valrubicin is usually administered at your doctor's office, hospital, or clinic.
  • If valrubicin contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Drinking extra fluids while you are taking valrubicin is recommended. Check with your doctor for instructions.
  • If you miss a dose of valrubicin, contact your doctor as soon as possible.

Ask your health care provider any questions you may have about how to use valrubicin.

Important safety information:

  • Valrubicin may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use valrubicin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If you get valrubicin on your skin, wash thoroughly with soap and water. If you get valrubicin in your eye, flush the eye with water.
  • Valrubicin may cause the urine to turn pink or red for the first 24 hours after you receive it. This is harmless and not a cause for concern. If the discoloration continues for more than 24 hours, contact your doctor right away.
  • Men should not father a child while being treated with valrubicin. Men should avoid having sex with a woman who may become pregnant while using valrubicin. Use an effective method of birth control. Check with your doctor if you have questions about using birth control.
  • Women should not become pregnant while being treated with valrubicin. Women who may become pregnant should use effective birth control during treatment with valrubicin. Check with your doctor if you have questions about using birth control.
  • Lab tests, including complete blood cell counts, bladder exams, and urine tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Valrubicin should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY AND BREAST-FEEDING: Valrubicin may cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using valrubicin while you are pregnant. It is not known if valrubicin is found in breast milk. Do not breast-feed while using valrubicin.

Possible side effects of valrubicin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bladder pain or spasm; burning or discomfort of the urethra; headache; irritable bladder symptoms (eg, frequent or painful urination, urgent need to urinate); loss of bladder control; mild dizziness, weakness, or tiredness; nausea; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (difficulty breathing; hives; itching; rash; swelling of the mouth, face, lips, or tongue; tightness in the chest); blood in the urine; chest pain; fever; inability to urinate; persistent red discoloration of the urine; severe or persistent bladder pain or spasms; severe or persistent painful urination, trouble urinating, or urinary urgency.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chills, fever, or sore throat; persistent red discoloration of the urine; severe or persistent bladder pain or spasms; severe or persistent painful urination, trouble urinating, or urinary urgency.

Proper storage of valrubicin:

Valrubicin is usually handled and stored by a health care provider. If you are using valrubicin at home, store valrubicin as directed by your pharmacist or health care provider. Keep valrubicin out of the reach of children and away from pets.

General information:

  • If you have any questions about valrubicin, please talk with your doctor, pharmacist, or other health care provider.
  • Valrubicin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take valrubicin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about valrubicin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to valrubicin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using valrubicin.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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