Generic Name: lactulose (LAK-tyoo-lose)
Brand Name: Examples include Enulose and Generlac
Lactulose solution is used for:
Preventing and treating portal-systemic encephalopathy. It may also be used for other conditions as determined by your doctor.
Lactulose solution is a colonic acidifier. It works by reducing blood ammonia levels, which reduces the degree of encephalopathy.
Do NOT use lactulose solution if:
- you are allergic to any ingredient in lactulose solution
Contact your doctor or health care provider right away if any of these apply to you.
Before using lactulose solution:
Some medical conditions may interact with lactulose solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diabetes, appendix problems, rectal bleeding, high blood galactose levels, or an intestinal blockage
Some MEDICINES MAY INTERACT with lactulose solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antacids because they may decrease lactulose solution's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if lactulose solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use lactulose solution:
Use lactulose solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Lactulose solution may be used orally or rectally.
- If taking lactulose solution by mouth, you may take it with or without food.
- If taking lactulose solution by mouth, you may mix lactulose solution with fruit juice, water, or milk. Drink one or more 8-ounce glasses of liquid with each dose.
- If you miss a dose of lactulose solution and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use lactulose solution.
Important safety information:
- It may take several days for lactulose solution to work.
- Diabetes patients - Lactulose solution may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
- LAB TESTS, including blood electrolyte levels, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using lactulose solution while you are pregnant. It is not known if lactulose solution is found in breast milk. If you are or will be breast-feeding while you use lactulose solution, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of lactulose solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Belching; gas; stomach cramps.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; high blood sugar (excessive thirst or urination, confusion, flushing, rapid breathing, or "fruity" breath odor).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; stomach cramps.Proper storage of lactulose solution:
Store lactulose solution at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Do not freeze. Keep tightly closed. A normal darkening of solution may occur under normal storage conditions. This will not affect the product. Exposure to temperatures above 86 degrees F (30 degrees C) will cause extreme darkening of the solution. Do not use the medicine if this occurs. Store away from heat, moisture, and light. Do not store in the bathroom. Keep lactulose solution out of the reach of children and away from pets.
- If you have any questions about lactulose solution, please talk with your doctor, pharmacist, or other health care provider.
- Lactulose solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take lactulose solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about lactulose solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to lactulose solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using lactulose solution.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.