Generic Name: ecallantide (e-KAL-lan-tide)
Brand Name: Kalbitor
Severe, and sometimes life-threatening, allergic reactions have occurred in patients who use Kalbitor. These symptoms can be similar to the condition you are being treated for, hereditary angioedema (HAE). Tell your doctor right away if you have any symptoms of an allergic reaction, including rash; hives; itching; difficulty breathing or swallowing; dizziness; fainting; fast or weak heartbeat; flushing; runny or stuffy nose; sneezing; tightness in the chest; swelling of the mouth, face, lips, or tongue; or unusual hoarseness. These reactions usually happen within 1 hour after receiving Kalbitor. Your doctor or nurse will watch you for any signs of an allergic reaction.
Kalbitor is used for:
Treating sudden attacks of HAE.
Kalbitor is a human plasma kallikrein inhibitor. It works by blocking substances that cause swelling, inflammation, and pain associated with HAE.
Do NOT use Kalbitor if:
- you are allergic to any ingredient in Kalbitor or have had a severe allergic reaction to Kalbitor
Contact your doctor or health care provider right away if any of these apply to you.
Before using Kalbitor:
Some medical conditions may interact with Kalbitor. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
Some MEDICINES MAY INTERACT with Kalbitor. However, no specific interactions with Kalbitor are known at this time.
Ask your health care provider if Kalbitor may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Kalbitor:
Use Kalbitor as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Kalbitor comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Kalbitor refilled.
- Kalbitor is usually given as an injection at your doctor's office, hospital, or clinic.
- Do not use Kalbitor if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Kalbitor, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Kalbitor.
Important safety information:
- Use Kalbitor with caution in the ELDERLY; they may be more sensitive to its effects.
- Kalbitor should be used with extreme caution in CHILDREN younger than 15 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: It is not known if Kalbitor can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Kalbitor while you are pregnant. It is not known if Kalbitor is found in breast milk. If you are or will be breast-feeding while you use Kalbitor, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Kalbitor:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; fatigue; headache; mild fever; mild irritation, redness, rash, swelling, itching, pain, or bruising at the injection site; nausea; sore throat; stomach pain; stuffy nose; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; dizziness; fainting; fast or weak heartbeat; flushing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); severe or persistent fever, chills, or sore throat; severe redness, rash, bruising, irritation, itching, swelling, or pain at the injection site.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Kalbitor:
Kalbitor is usually handled and stored by a health care provider. If you are using Kalbitor at home, store Kalbitor as directed by your pharmacist or health care provider. Keep Kalbitor out of the reach of children and away from pets.
- If you have any questions about Kalbitor, please talk with your doctor, pharmacist, or other health care provider.
- Kalbitor is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Kalbitor or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Kalbitor. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Kalbitor. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Kalbitor.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.