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Generic Name: ertapenem (ER-ta-PEN-em)
Brand Name: Invanz

Invanz is used for:

Treating moderate to severe infections caused by certain bacteria. It is also used to prevent infection after certain types of surgery. It may also be used for other conditions as determined by your doctor.

Invanz is a carbapenem antibiotic. It works by killing sensitive bacteria.

Do NOT use Invanz if:

  • you are allergic to any ingredient in Invanz or to any other beta-lactam antibiotic (eg, imipenem)
  • you are receiving Invanz as an injection into your muscle and you are allergic to local anesthetics of the amide type (eg, lidocaine)
  • you are taking probenecid

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Invanz:

Some medical conditions may interact with Invanz. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had an allergic reaction (eg, rash, hives, itching, difficulty breathing, swelling, dizziness) to a penicillin antibiotic (amoxicillin) or cephalosporin antibiotic (eg, cephalexin)
  • if you receive dialysis treatments, have kidney problems or bladder problems, or have a history of central nervous system problems (eg, brain lesions, seizures)

Some MEDICINES MAY INTERACT with Invanz. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Probenecid because it may increase the risk of Invanz's side effects
  • Divalproex sodium or valproic acid because their effectiveness may be decreased by Invanz

This may not be a complete list of all interactions that may occur. Ask your health care provider if Invanz may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Invanz:

Use Invanz as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Invanz is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Invanz at home, a health care provider will teach you how to use it. Be sure you understand how to use Invanz. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Invanz if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • To clear up your infection completely, use Invanz for the full course of treatment. Keep using it even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Invanz, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Invanz.

Important safety information:

  • Invanz may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Invanz with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Be sure to use Invanz for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Invanz only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Long-term or repeated use of Invanz may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Lab tests, including kidney function, liver function, and complete blood cell counts, may be performed while you use Invanz. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Invanz with caution in the ELDERLY; they may be more sensitive to its effects.
  • Invanz should not be used in CHILDREN younger than 3 months old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Invanz while you are pregnant. Invanz is found in breast milk. If you are or will be breast-feeding while you use Invanz, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Invanz:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; minor pain, swelling, or redness at the injection site; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; chest pain; decreased coordination; decreased urination; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; mental or mood changes (eg, agitation, anxiety, confusion); muscle weakness; seizures; severe or persistent diarrhea; severe or persistent dizziness or headache; severe pain, swelling, or redness at the injection site; severe stomach cramps; severe stomach or back pain (with or without nausea or vomiting); shortness of breath; sudden, unexplained weight gain; swelling of hands or feet; tremors or abnormal muscle movements; trouble swallowing; trouble walking; unusual vaginal odor or discharge; vomit that looks like coffee grounds; white patches in the mouth; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; dizziness; nausea.

Proper storage of Invanz:

Invanz is usually handled and stored by a health care provider. If you are using Invanz at home, store Invanz as directed by your pharmacist or health care provider. Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Invanz out of the reach of children and away from pets.

General information:

  • If you have any questions about Invanz, please talk with your doctor, pharmacist, or other health care provider.
  • Invanz is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Invanz or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Invanz. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Invanz. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Invanz.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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