Generic Name: dextromethorphan/guaifenesin/phenylephrine (dex-troe-meth-OR-fan/gwye-FEN-e-sin/fen-ill-EF-rin)
Brand Name: Examples include Nortuss-DE and Zotex Pediatric
Dextromethorphan/guaifenesin/phenylephrine drops is used for:
Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.
Dextromethorphan/guaifenesin/phenylephrine drops is a decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, loosening mucus and lung secretions in the chest, and making coughs more productive. It also works in the brain to help decrease the cough reflex to reduce a dry cough.
Do NOT use dextromethorphan/guaifenesin/phenylephrine drops if:
- you are allergic to any ingredient in dextromethorphan/guaifenesin/phenylephrine drops
- you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
- you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using dextromethorphan/guaifenesin/phenylephrine drops:
Some medical conditions may interact with dextromethorphan/guaifenesin/phenylephrine drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke
- if you have a chronic cough, lung problems (eg, asthma, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if cough occurs with large amounts of mucus
Some MEDICINES MAY INTERACT with dextromethorphan/guaifenesin/phenylephrine drops. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects from dextromethorphan/guaifenesin/phenylephrine drops may be increased
- Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
- Bromocriptine because the risk of side effects may be increased by dextromethorphan/guaifenesin/phenylephrine drops
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by dextromethorphan/guaifenesin/phenylephrine drops
This may not be a complete list of all interactions that may occur. Ask your health care provider if dextromethorphan/guaifenesin/phenylephrine drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use dextromethorphan/guaifenesin/phenylephrine drops:
Use dextromethorphan/guaifenesin/phenylephrine drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Dextromethorphan/guaifenesin/phenylephrine drops may be taken with or without food.
- Drink plenty of water while taking dextromethorphan/guaifenesin/phenylephrine drops.
- Use the dropper that comes with dextromethorphan/guaifenesin/phenylephrine drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you miss a dose of dextromethorphan/guaifenesin/phenylephrine drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use dextromethorphan/guaifenesin/phenylephrine drops.
Important safety information:
- Dextromethorphan/guaifenesin/phenylephrine drops may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to dextromethorphan/guaifenesin/phenylephrine drops. Using dextromethorphan/guaifenesin/phenylephrine drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
- Do not take appetite suppressants while you are taking dextromethorphan/guaifenesin/phenylephrine drops without checking with your doctor.
- Dextromethorphan/guaifenesin/phenylephrine drops contains phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.
- Do NOT exceed the recommended dose or take dextromethorphan/guaifenesin/phenylephrine drops for longer than prescribed without checking with your doctor.
- If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
- Dextromethorphan/guaifenesin/phenylephrine drops may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking dextromethorphan/guaifenesin/phenylephrine drops.
- Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using dextromethorphan/guaifenesin/phenylephrine drops.
- Use dextromethorphan/guaifenesin/phenylephrine drops with caution in the ELDERLY because they may be more sensitive to its effects.
- Caution is advised when using dextromethorphan/guaifenesin/phenylephrine drops in CHILDREN because they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking dextromethorphan/guaifenesin/phenylephrine drops, discuss with your doctor the benefits and risks of using dextromethorphan/guaifenesin/phenylephrine drops during pregnancy. It is unknown if dextromethorphan/guaifenesin/phenylephrine drops is excreted in breast milk. Do not breast-feed while taking dextromethorphan/guaifenesin/phenylephrine drops.
Possible side effects of dextromethorphan/guaifenesin/phenylephrine drops:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.
This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.Proper storage of dextromethorphan/guaifenesin/phenylephrine drops:
Store dextromethorphan/guaifenesin/phenylephrine drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep dextromethorphan/guaifenesin/phenylephrine drops out of the reach of children and away from pets.
- If you have any questions about dextromethorphan/guaifenesin/phenylephrine drops, please talk with your doctor, pharmacist, or other health care provider.
- Dextromethorphan/guaifenesin/phenylephrine drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about dextromethorphan/guaifenesin/phenylephrine drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.