Generic Name: basiliximab (bass-ih-LIX-ih-mab)
Brand Name: Simulect
Basiliximab is used for:
Preventing organ rejection in kidney transplant patients. It is used in combination with other medicines. It may also be used for other conditions as determined by your doctor.
Basiliximab is a monoclonal antibody. It works by blocking the immune response that causes transplant rejection.
Do NOT use basiliximab if:
- you are allergic to any ingredient in basiliximab
Contact your doctor or health care provider right away if any of these apply to you.
Before using basiliximab:
Some medical conditions may interact with basiliximab. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have cancer or an infection, or if you have been very ill
Some MEDICINES MAY INTERACT with basiliximab. However, no specific interactions with basiliximab are known at this time.
This may not be a complete list of all interactions that may occur. Ask your health care provider if basiliximab may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use basiliximab:
Use basiliximab as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Basiliximab is usually administered as an injection at your doctor's office, hospital, or clinic.
- If you miss a dose of basiliximab, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use basiliximab.
Important safety information:
- Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using basiliximab.
- Basiliximab may cause high blood sugar (eg, thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, fruity breath odor). If these symptoms occur, tell your doctor immediately.
- Basiliximab may lower your resistance to infection. Prevent infection by avoiding contact with people with colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first.
- Consult your doctor before having any vaccinations while you are using basiliximab.
- Use basiliximab with caution in the ELDERLY because they may be more sensitive to its effects.
- Women of childbearing age should use an effective form of birth control before, during, and for 4 months after using basiliximab.
- PREGNANCY and BREAST-FEEDING: Avoid becoming pregnant while you are using basiliximab. If you think you may be pregnant, discuss with your doctor the benefits and risks of using basiliximab during pregnancy. It is unknown if basiliximab is excreted in breast milk. Do not breast-feed while taking basiliximab.
Possible side effects of basiliximab:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Acne; constipation; diarrhea; headache; indigestion; nausea; runny nose; sleeplessness; stomach pain; tremor; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark, bloody stools; dizziness; fast heartbeat; fever, chills, or sore throat; increased thirst or urination; painful urination; pain, swelling, or redness at injection site; pain, swelling, or redness at surgical site; shortness of breath; swelling of the hands or feet; unusual sneezing; unusual weakness or tiredness; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of basiliximab:
Basiliximab will be stored by your health care provider. Keep basiliximab out of the reach of children and away from pets.
- If you have any questions about basiliximab, please talk with your doctor, pharmacist, or other health care provider.
- Basiliximab is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take basiliximab or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about basiliximab. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to basiliximab. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using basiliximab.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.