No information is available on the clinical use of sugammadex during breastfeeding. Because sugammadex is a large, highly polar molecule with a molecular weight of 2002 Da., the amount in milk is likely to be very low and oral absorption by the infant is unlikely. Sugammadex is acceptable to use during breastfeeding.[1-3]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Reece-Stremtan S, Campos M, Kokajko L, et al. ABM Clinical Protocol #15: Analgesia and anesthesia for the breastfeeding mother, revised 2017. Breastfeed Med. 2017;12:500–6. [PubMed: 29624435]
2.
Richardson MG, Raymond BL. Sugammadex administration in pregnant women and in women of reproductive potential: A narrative review. Anesth Analg. 2020;130:1628–37. [PubMed: 31283616]
3.
Hirsch JG, Chia PA, Jahr JS. Sugammadex: A review of the considerations for women of childbearing age. Am J Ther. 2023;30:e146–e150. [PubMed: 36892560]
Substance Identification
Substance Name
Sugammadex
CAS Registry Number
343306-71-8
Drug Class
Breast Feeding
Lactation
Milk, Human
Antidotes
Gamma-Cyclodextrins
Neuromuscular Blockade
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
