Nitroglycerin use while Breastfeeding

Drugs containing Nitroglycerin: Nitrostat, NitroQuick, Nitro-Dur, Tridil, Nitro-Bid, Minitran, Nitrol, Nitrolingual Pumpspray, Nitrostat Tablets, Transderm-Nitro, Show all 24 »Rectiv, Nitro TD Patch-A, NitroMist, Deponit, Nitroglyn E-R, Nitrodisc, Nitrek, Nitro-Par, Nitro-Time, Nitrocot, Nitrogard, Nitrol Appli-Kit, Nitrong, Nitro-Bid IV

Nitroglycerin Levels and Effects while Breastfeeding

Summary of Use during Lactation

Topical use of nitroglycerin for anal fissures by nursing mothers appears to have no adverse effects on their breastfed infants. Sublingual and intravenous nitroglycerin have not been studied during breastfeeding. Observe infants for flushing and discomfort after breastfeeding.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Forty nursing mothers used nitroglycerin ointment (dosage not specified) topically for the treatment of postpartum anal fissures for durations ranging from 1 use to 12 months of intermittent use. All but 9 of the women reported side effects from therapy, primarily headache, but also dizziness or lightheadedness. None of the mothers reported any side effects in their breastfed infants.[1]

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

References

1. Taylor T, Kennedy D. Safety of topical glyceryl trinitrate in the treatment of anal fissure in breastfeeding women. Birth Defects Research Part a-Clinical and Molecular Teratology. 2008;82:411. Abstract.

Nitroglycerin Identification

Substance Name

Nitroglycerin

CAS Registry Number

55-63-0

Drug Class

Administrative Information

LactMed Record Number

626

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2008-07-16

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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