Isotretinoin use while Breastfeeding
Drugs containing Isotretinoin: Accutane, Claravis, Amnesteem, Absorica, Zenatane, Myorisan, Sotret
Isotretinoin Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the use of isotretinoin during breastfeeding. Various topical agents that are less likely to be absorbed by the mother may be preferred during breastfeeding, especially while nursing a newborn or preterm infant.
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
A woman who had weaned her infant 18 months previously developed a nipple discharge from her right breast after 5.5 months of therapy with isotretinoin. Microbiological, hormonal (including prolactin), radiologic, and physical examinations were otherwise normal. One month after discontinuing isotretinoin, the discharge ceased. After isotretinoin was reinstituted at the same dose, the discharge reappeared within 10 days. The galactorrhea was probably caused by isotretinoin.
Alternate Drugs to Consider
Larsen GK. Iatrogenic breast discharge with isotretinoin. Arch Dermatol. 1985;121:450-1. PMID: 3856419
CAS Registry Number
- Dermatologic Agents
- Keratolytic Agents
LactMed Record Number
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- Isotretinoin use during Pregnancy
- Isotretinoin Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy