Eletriptan use while Breastfeeding
Drugs containing Eletriptan: Relpax
Eletriptan Levels and Effects while Breastfeeding
Summary of Use during Lactation
Limited information indicates that a maternal dose of eletriptan up to 80 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.
Drug Levels
Maternal Levels. Eight lactating women who were at least 1 month postpartum were given a single 80 mg oral dose of eletriptan. An average of 12.9 mcg was excreted in the 24 hours after the dose. At 24 hours, breastmilk levels averaged 1.7 mcg/L. The half-life in milk of eletriptan was 3.6 hours.[1] Although the active metabolite was not measured in breastmilk and it has a longer half-life than eletriptan, its serotonin agonist activity is only about 10% that of eletriptan.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
1. FDA Center for Drug Evaluation and Research. NDA 21-016. Clinical pharmacology and biopharmaceutics reviews. http://www.fda.gov/cder/foi/nda/2002/21016_Relpax_BioPharmr.pdf. 2002;8-9. Accessed 11/3/03.
Eletriptan Identification
Substance Name
CAS Registry Number
177834-92-3
Drug Class
- Serotonin Agonists
Administrative Information
LactMed Record Number
350
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2007-12-27
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Eletriptan use during Pregnancy
- Eletriptan Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
