Busulfan use while Breastfeeding
Drugs containing Busulfan: Myleran, Busulfex
Busulfan Levels and Effects while Breastfeeding
Summary of Use during Lactation
Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Busulfan in a dosage of 4 mg daily for 5 weeks was taken for myeloid leukemia by one woman while breastfeeding. Weekly monitoring found no adverse effects on her infant's leukocyte count or hemoglobin.[1]
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Dependent on the condition being treated.
References
1. Bounameaux Y, Durenne JM. [A case of leukemia in a lactating female: effect of treatment with busulfan on the infant]. Ann Soc Belge Med Trop. 1964;44:381-3. PMID: 14259241
Busulfan Identification
Substance Name
CAS Registry Number
55-98-1
Drug Class
- Antineoplastic Agents
Administrative Information
LactMed Record Number
37
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2012-10-02
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Busulfan use during Pregnancy
- Busulfan Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
