Menopause - how long does it take for estradiol to start working?

27 Oct 2011

Hi
I had a total hysterectomy a few years ago and when the doctor put me on estradiol it worked right away. I used the transdermal patch because I didn't want to take the pills. Somettimes it takes about a day or two, but you'll start to notice the difference. It did cut down my hot flashes and the moodiness for me.

27 Oct 2011

Hi, I am presently on EstroGel--transdermal estradiol gel applied to arm daily-- Vagifem--an estradiol pill placed in vagina 2x week-- and ProGest bioidentical progesterone cream. It took two days for me to start feeling better on the Vagifem, four days and I was feeling close to my old self. (I had a hysterectomy in '09 and still have ovaries.) My gyn started me on Vagifem in March 2010 and EstroGel six weeks later as my body didn't like not getting the loading dose of Vagifem on a regular continuing basis. I am very sensitive to ANY change in horomone levels. So depending on how sensitive you are, what form and dose of estradiol you are receiving, and how much your body needs, might be faster or slower before full effect has been reached. I've heard that it could take as long as two to six weeks. Good luck to you and may you become "balanced" again soon!
Take care, and be well, Lady of Howard