I am currently taking synthroid 175 mcg in the morning on an empty stomach and then 30 minutes to an hour later take linzess 145 mcg for constipation. However, I am reading that this may reduce the effectiveness of my synthroid absorption which my doctor told me nothing about. How should these medications be taken together? Should they be taken together at all? And if I eat a high-fiber diet due to constipation, when can I eat high-fiber cereals or fruits after taking synthroid?