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Scans Suggest Recurrent Depression May Take Toll on the Brain

Posted 4 days ago by Drugs.com

TUESDAY, June 30, 2015 – The area of the brain involved in forming new memories, known as the hippocampus, seems to shrink in people with recurring depression, a new study shows. Australian researchers say the findings highlight the need to spot and treat depression when it first develops, particularly among young people. Ian Hickie, who co-directs the Brain and Mind Research Institute at the University of Sydney, led the study. His team looked at the neurology of almost 9,000 people from the United States, Europe and Australia. To do so, they analyzed brain scans and medical data for about 1,700 people with major depression, and almost 7,200 people who didn't suffer from depression. The researchers noted that 65 percent of the participants with major depression had suffered recurring symptoms. The study, published June 30 in the journal Molecular Psychiatry, found that people with ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Trazodone, Citalopram, Pristiq, Sertraline, Viibryd, Amitriptyline, Bupropion, Effexor XR, Fluoxetine, Venlafaxine, Major Depressive Disorder

As U.S. Smoking Rate Drops, Smokers More Likely to Quit: Study

Posted 9 days ago by Drugs.com

THURSDAY, June 25, 2015 – As the number of smokers in the United States dwindles, those who still light up are becoming less attached to the habit and more likely to try quitting, a new study has found. These findings run counter to the theory of "hardening," which has held that as smoking rates decline those who still smoke will be increasingly committed to their habit, said study author Margarete Kulik, a postdoctoral fellow with the Center for Tobacco Control Research and Education at the University of California, San Francisco. "The assumption is as smoking prevalence decreases, those smokers who are left will be the hardcore smokers who are unable or unwilling to quit," Kulik said. "We found out that there is not hardening. There is softening. There is actually more quitting, and people smoke less." The study was published online June 24 in the journal Tobacco Control. Dr. Norman ... Read more

Related support groups: Wellbutrin, Smoking, Bupropion, Chantix, Wellbutrin XL, Smoking Cessation, Wellbutrin SR, Nicotine, Zyban, Nicorette, Champix, Nicoderm CQ, Nicotrol Inhaler, Aplenzin, Budeprion, Commit, Budeprion XL, Zyban Advantage Pack, Varenicline, Buproban

FDA Seizes Counterfeit Drugs, Devices Sold Online

Posted 16 days ago by Drugs.com

THURSDAY, June 18, 2015 – The U.S. Food and Drug Administration, along with international partners, moved this week against more than 1,050 websites that sell potentially dangerous counterfeit medicines and medical devices, the agency said Thursday. Illegal medicines and medical devices were seized worldwide, and warnings were sent to the operators of offending websites, the FDA said in a news release. "Our efforts to protect the health of American patients by preventing the online sale of potentially dangerous illegal medical products will not cease," said George Karavetsos, director of the FDA's Office of Criminal Investigations. Counterfeit prescription drugs that claim to be generic versions of brand-name drugs that are sold illegally on the websites include generic Nolvadex, generic Meridia, generic Valium, generic Truvada and generic Advair Diskus, according to the FDA. Mail ... Read more

Related support groups: Depression, Sleep Disorders, Insomnia, Wellbutrin, Valium, Erectile Dysfunction, Viibryd, Bupropion, Major Depressive Disorder, Wellbutrin XL, Wellbutrin SR, Brintellix, Advair Diskus, Zyban, 5-HTP, Meridia, St. John's Wort, Truvada, Aplenzin, Budeprion

More U.S. Kids Getting Mental Health Treatment

Posted 20 May 2015 by Drugs.com

WEDNESDAY, May 20, 2015 – The number of U.S. children and teens being treated for mental health issues has risen by about 50 percent in the past 20 years – with most of those kids having relatively mild symptoms, a new study finds. The research, published in the May 21 issue of the New England Journal of Medicine, comes at a time of growing concern over young people's mental health treatment. In particular, some worry that kids with milder issues are being overtreated with antidepressants, stimulants (such as those used for attention deficit hyperactivity disorder) and antipsychotic drugs, said lead researcher Dr. Mark Olfson, a professor of clinical psychiatry at Columbia University in New York City. According to Olfson, his findings suggest that kids with less serious symptoms account for a large share of young people getting mental health care – whether that means medication or ... Read more

Related support groups: Depression, Attention Deficit Hyperactivity Disorder (ADHD), Anxiety and Stress, Adderall, Wellbutrin, Phentermine, Vyvanse, Viibryd, Social Anxiety Disorder, Bupropion, Concerta, Ritalin, Major Depressive Disorder, Adderall XR, Amphetamine, Wellbutrin XL, Adipex-P, Strattera, Focalin, Nuvigil

Even Treated Depression May Raise Stroke Risk

Posted 13 May 2015 by Drugs.com

WEDNESDAY, May 13, 2015 – Depression in older adults appears to significantly increase the risk of a stroke, even after depression symptoms have gotten better, a new study suggests. The researchers found that people who had severe symptoms of depression were more than twice as likely to have a stroke as those with no symptoms. People who had symptoms at the first interview, but had gotten better by the second interview still had a 66 percent higher stroke risk, the study authors said. "The surprising finding that stroke risk remains elevated even if symptoms seem to have gone away make replicating this study urgent," said lead researcher Paola Gilsanz, a research fellow at Harvard University's T.H. Chan School of Public Health in Boston. "If replicated, these findings suggest that doctors should seek to identify and treat depressive symptoms before harmful effects on stroke risk start ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Trazodone, Citalopram, Pristiq, Sertraline, Viibryd, Amitriptyline, Bupropion, Effexor XR, Ischemic Stroke, Fluoxetine, Venlafaxine

Ban Flavoring, Ads for E-Cigarettes, Doctors' Group Says

Posted 22 Apr 2015 by Drugs.com

WEDNESDAY, April 22, 2015 – The U.S. Food and Drug Administration should ban flavorings and television ads for e-cigarettes, a prominent physicians' organization says. There is scant evidence that e-cigarettes help people quit smoking, as claimed by manufacturers. And the chemicals used in these devices may be harmful to both smokers and bystanders, said Ryan Crowley, senior associate for health policy at the American College of Physicians (ACP). "There are over 7,000 different flavorings in e-cigarettes, and the evidence shows that young people are attracted to these products because of the flavors," Crowley said. "There are also concerns that there are harmful chemicals in the flavorings themselves." Crowley added that calling for a ban on TV ads for e-cigarettes follows ACP's continuing policy supporting bans on all tobacco advertising. The organization also recommends taxing ... Read more

Related support groups: Wellbutrin, Smoking, Bupropion, Chantix, Wellbutrin XL, Smoking Cessation, Wellbutrin SR, Nicotine, Zyban, Nicorette, Champix, Nicoderm CQ, Nicotrol Inhaler, Aplenzin, Budeprion, Commit, Budeprion XL, Zyban Advantage Pack, Varenicline, Buproban

Weight Gain From Antidepressants Is Minimal, Study Suggests

Posted 5 Jun 2014 by Drugs.com

THURSDAY, June 5, 2014 – While it has long been known that some antidepressants can help spur weight gain, a new study finds that the actual amount gained is usually small. "This study was motivated in the first place by the number of patients who have asked me if their medicine is going to make them gain weight," said study co-author Dr. Roy Perlis, director of Massachusetts General Hospital's Center for Experimental Drugs and Diagnostics, in Boston. "It's the most common question I get when prescribing any medication, frankly," he said. "But most antidepressant studies have been short term, looking at just a few months of treatment. So I wanted to look at it for a longer period of time," Perlis explained. "I think our findings should be reassuring to patients. Yes, antidepressants can lead in some cases to small amounts of weight gain, that's true. And we need to pay attention to it, ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Citalopram, Sertraline, Amitriptyline, Bupropion, Effexor XR, Fluoxetine, Venlafaxine, Mirtazapine, Wellbutrin XL, Remeron, Nortriptyline

Drug Duo Might Help Smokers Quit Better Than Single Med

Posted 7 Jan 2014 by Drugs.com

TUESDAY, Jan. 7, 2014 – Two drugs in combination might be better than one when it comes to helping hardcore smokers quit, at least in the short term, a new study suggests. The drugs – varenicline (sold under the brand name Chantix) and bupropion (Zyban) – taken together increase the rates of quitting over 12 weeks compared with Chantix alone, the researchers found. After a year, however, relapse rates were similar using both approaches. "We believe this evidence strongly supports the idea that varenicline helps everybody quit," said lead researcher Dr. Jon Ebbert, a professor of medicine at the Mayo Clinic in Rochester, Minn. "But for heavier smokers and more dependent smokers, combination therapy with varenicline plus bupropion will increase quit rates more than varenicline alone." "This is how we are going to treat patients," he said. Combination therapy works better than a single ... Read more

Related support groups: Wellbutrin, Bupropion, Chantix, Wellbutrin XL, Smoking Cessation, Wellbutrin SR, Zyban, Champix, Aplenzin, Budeprion, Budeprion XL, Zyban Advantage Pack, Varenicline, Buproban, Budeprion SR

Psychiatric Drugs More Often Prescribed in the South

Posted 1 Feb 2013 by Drugs.com

FRIDAY, Feb. 1 – Use of psychiatric medications is most prevalent in the southern United States and least prevalent in the West, according to a new U.S. study. Although people living in the West are the least likely to use antipsychotics, antidepressants and stimulants, the Yale researchers found that the drugs' use is 40 percent higher in a large section of the South than in other parts of the country. The study authors attributed this discrepancy to variations in local access to health care and marketing efforts within the pharmaceutical industry. "The geographic patterns we identify are striking and map onto the patterns found for a host of other medical conditions and treatments, from cognitive decline to bypass surgery," Marissa King, assistant professor of organizational behavior at the Yale School of Management, said in a school news release. "Our work suggests that access to ... Read more

Related support groups: Depression, Bipolar Disorder, Lexapro, Adderall, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Seroquel, Celexa, Paxil, Phentermine, Trazodone, Citalopram, Vyvanse, Abilify, Lithium, Pristiq, Sertraline

FDA Pulls One Generic Form of Wellbutrin Off the Market

Posted 5 Dec 2012 by Drugs.com

WEDNESDAY, Dec. 5 – People taking the antidepressant Wellbutrin now have one less option for a generic version of the drug. In October, the U.S. Food and Drug Administration recommended that generic Wellbutrin, or bupropion, made by Impax Laboratories and distributed by Teva Pharmaceuticals, be taken off the market, and Impax and Teva have agreed to stop shipping the drug. The decision is based on an FDA study that found that the extended release (XL) form of bupropion – Budeprion XL – at the 300 milligram (mg) dose was not bioequivalent to brand-name Wellbutrin XL at the same dose, suggesting that it may not be as safe and effective. The study was published Dec. 5 in the New England Journal of Medicine. Four other manufacturers make bupropion XL in 300 mg tablets, and patients can still get their prescription filled with these products. "The other four generic versions of 300 mg ... Read more

Related support groups: Wellbutrin, Bupropion, Wellbutrin XL, Wellbutrin SR, Zyban, Aplenzin, Budeprion, Budeprion XL, Zyban Advantage Pack, Buproban, Budeprion SR

FDA Update: Budeprion XL 300 mg Not Therapeutically Equivalent to Wellbutrin XL 300 mg

Posted 9 Oct 2012 by Drugs.com

October 3, 2012 – The U.S. Food and Drug Administration (FDA) has reviewed new data that indicate Budeprion XL 300 mg (bupropion hydrochloride extended-release tablets), manufactured by Impax Laboratories, Inc., and marketed by Teva Pharmaceuticals USA, Inc., is not therapeutically equivalent to Wellbutrin XL 300 mg. FDA has changed the therapeutic equivalence rating for this product in the Agency’s Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) from AB to BX, signifying that Budeprion XL 300 mg fails to demonstrate therapeutic equivalence to Wellbutrin XL 300 mg. Impax has requested that the Agency withdraw approval of budeprion XL 300 mg extended-release tablets. Impax and Teva have stopped shipping the product and are issuing detailed information to their customers. This announcement relates only to Budeprion XL 300 mg manufactured by Impax and m ... Read more

Related support groups: Wellbutrin, Bupropion, Wellbutrin XL, Wellbutrin SR, Zyban, Aplenzin, Budeprion, Budeprion XL, Zyban Advantage Pack, Buproban, Budeprion SR

Genes Might Help Some Smokers Kick the Habit

Posted 31 May 2012 by Drugs.com

THURSDAY, May 31 – Smokers' genes may help predict whether they'll respond to drug treatments for nicotine addiction, a new study indicates. Researchers analyzed data from more than 6,000 smokers in community-based studies and a clinical treatment study and found that the same gene variations that make it difficult to stop smoking also increase the chances that heavy smokers will respond to nicotine-replacement therapy and drugs that reduce the craving for nicotine. "People with the high-risk genetic markers smoked an average of two years longer than those without these high-risk genes, and they were less likely to quit smoking without medication," study first author Dr. Li-Shiun Chen, an assistant professor of psychiatry at Washington University of Medicine in St. Louis, said in a university news release. "The same gene variants can predict a person's response to smoking-cessation ... Read more

Related support groups: Wellbutrin, Smoking, Bupropion, Wellbutrin XL, Smoking Cessation, Wellbutrin SR, Nicotine, Zyban, Nicorette, Nicoderm CQ, Nicotrol Inhaler, Aplenzin, Budeprion, Commit, Budeprion XL, Zyban Advantage Pack, Buproban, Habitrol, Budeprion SR, Nicotrol NS

Minorities, Medicare Recipients Less Likely to Get Antidepressants

Posted 9 Apr 2012 by Drugs.com

MONDAY, April 9 – Hispanics and blacks are less likely to be prescribed antidepressants than whites, and Medicare and Medicaid patients are less likely to receive the drugs than those with private insurance, a new study says. University of Michigan School of Public Health researchers examined data from 1993 to 2007 and found that whites were 1.5 times more likely to receive antidepressants than blacks or Hispanics with major depression. The study also found that Medicare and Medicaid patients were 31 percent and 38 percent less likely to be prescribed antidepressants than privately insured patients. Race didn't play a role in the type of antidepressants prescribed to patients, but insurance did. Medicare and Medicaid patients were 58 percent and 61 percent less likely to receive newer antidepressants than privately insured patients. Newer types of antidepressants such as serotonin ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Trazodone, Citalopram, Pristiq, Sertraline, Viibryd, Amitriptyline, Bupropion, Effexor XR, Fluoxetine, Venlafaxine, Mirtazapine

Prescription Meds Can Put on Unwanted Pounds

Posted 2 Mar 2012 by Drugs.com

FRIDAY, March 2 – Medications taken by millions of Americans for mood disorders, high blood pressure, diabetes and other chronic conditions can have an unhealthy side effect: weight gain. While other choices exist for some types of drugs, adjusting medications is not simply a matter of switching, said Ryan Roux, chief pharmacy officer with the Harris County Hospital District, in Houston. In the late 1990s, Dr. Lawrence Cheskin conducted early research on prescription medicines and obesity. "Some medicines make an early, noticeable difference, causing patients to become ravenously hungry, while changes are subtle for others. A few months taking them and you've gained 10 pounds," said Cheskin, now director of the Johns Hopkins Weight Management Center, in Baltimore. To help increase awareness, Roux and his pharmacist group have compiled a list of "weight-promoting" and "weight-neutral or ... Read more

Related support groups: Bipolar Disorder, Plan B, High Blood Pressure, Zoloft, Diabetes, Type 2, Wellbutrin, Prozac, Prednisone, Gabapentin, Seroquel, Metformin, Sprintec, Mirena, NuvaRing, Implanon, Hypertension, Provera, Paxil, Lamictal, Metoprolol

Best Antidepressant May Depend on Patient: Study

Posted 5 Dec 2011 by Drugs.com

TBD – Newer antidepressants seem to be about as effective as one another, a new analysis indicates. This suggests that the choice of which drug is appropriate for which patient should be made on the basis of such considerations as side effects, cost and patient preference. "They're all equally effective," said Dr. David Schlager, a clinical assistant professor of psychiatry and behavioral science at Texas A&M Health Science Center College of Medicine. "They're interchangeable except for side effects," he added, so psychiatrists do tend to "exploit the side-effect profile" to find suitable medications for individual patients, he added. According to the background information in the new study, appearing in the Dec. 6 issue of Annals of Internal Medicine, some 27 million people in the United States had taken antidepressants as of 2005. Most of these drugs are "second-generation" ... Read more

Related support groups: Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Citalopram, Pristiq, Sertraline, Bupropion, Effexor XR, Fluoxetine, Venlafaxine, Savella, Wellbutrin XL, Escitalopram, Wellbutrin SR, Paroxetine

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