Shift Work Sleep Disorder Blog
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Drug Effective for Temporary Sleep Disruptions
Posted 3+ months ago by Drugs.com
TUESDAY, Dec. 2 – The experimental drug tasimelteon helps treat temporary insomnia caused by jet lag or night shifts, according to the results of two new clinical trials.
The phase II study included 39 people randomly assigned to receive either 10 milligrams, 20 mg, 50 mg or 100 mg of tasimelteon, or a placebo. They were monitored for seven nights – three at baseline, three after a five-hour advance of sleep-wake schedule with treatment before sleep, and one night after treatment.
The phase III trial included 411 people who had transient insomnia induced in a sleep clinic by a five-hour advance of their sleep-wake cycle. They received either 20 mg, 50 mg, or 100 mg of tasimelteon, or a placebo, 30 minutes before bedtime. Read more...
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