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Depomed Announces US Food and Drug Administration Approval of Gralise (gabapentin) Once-Daily Tablets for Treatment of Post-Herpetic Neuralgia

Posted 2 Feb 2011 by Drugs.com

MENLO PARK, Calif., Jan 28, 2011 - --Depomed, Inc. today announced that US FDA has approved Gralise (gabapentin) Tablets for once-daily treatment of post-herpetic neuralgia (PHN), which is pain following healing of the rash associated with shingles. Gralise was developed by Depomed under the code name DM-1796 and is licensed to Abbott Products, Inc. in the U.S., Canada and Mexico. The approval of Gralise triggers a milestone payment of $48 million from Abbott to Depomed. "The approval of Gralise is a major step toward achieving our key strategic objective of sustainable profitability in 2011 and beyond," said Carl Pelzel, President and CEO of Depomed. "I'd like to thank everyone on the Depomed and Abbott teams involved in the development and approval of this important therapy for their hard work and dedication," added Mr. Pelzel. Michael Sweeney, MD, Vice President of Research and ... Read more

Related support groups: Gabapentin, Persisting Pain, Shingles

Drug Combo May Offer Best Relief for Nerve Pain

Posted 16 Jul 2010 by Drugs.com

TUESDAY, Sept. 29 – People with nerve pain respond better to a combination treatment using the anticonvulsant gabapentin and antidepressant nortriptyline than to treatment with either drug alone, according to Canadian researchers. The study findings suggest that combination treatment could be used to help people who only partially respond to one drug or the other. Nerve, or neuropathic, pain – which affects 2 to 3 percent of the population – is "initiated or caused by a primary lesion or dysfunction in the nervous system," according to a news release from The Lancet, which is publishing the study online Sept. 29. Conditions that cause neuropathic pain include nerve problems in the spine, diabetes-related nerve damage and postherpetic neuralgia (PHN), which is nerve pain caused by the varicella zoster virus that can follow an outbreak of shingles. The study included 56 people with PHN ... Read more

Related support groups: Gabapentin, Neurontin, Neuralgia, Nortriptyline, Persisting Pain, Shingles, Diabetic Neuropathy, Diabetic Nerve Damage, Postherpetic Neuralgia, Pamelor, Gabarone, Aventyl HCl

Oxycodone May Reduce Shingles Pain

Posted 10 Apr 2009 by Drugs.com

FRIDAY, April 10 – A new study finds oxycodone, often known as OxyContin, successfully reduces the sometimes excruciating pain of shingles. Shingles, an often stress-related condition resulting from the same virus that causes chicken pox, causes pain, blisters, rash and flu-like symptoms that antiviral medications usually help alleviate within a month. However, if the pain component is not effectively treated during the course of the illness, the patient has a greater chance of the pain lasting months or even years after the other symptoms have subsided, the study authors noted. The long-term pain comes from the varicella zoster virus damaging nerves during the infection period. The condition, called postherpetic neuralgia, affects up to a quarter of shingles patients and can cause shooting or burning pain, an electric shock feeling in the body or skin highly sensitive to touch. "For ... Read more

Related support groups: Persisting Pain, Shingles

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gabapentin, Lyrica, Neurontin, clonidine, nortriptyline, pregabalin, Lidoderm, Catapres, Gralise, view more... Horizant, capsaicin, Capzasin, Zostrix, Capzasin-HP, gabapentin enacarbil systemic, Capzasin-P, Icy Hot PM, Trixaicin, Zostrix-HP, Gabarone, Dolorac, Axsain, Qutenza, Pain-X, R-Gel, RT Capsin, Salonpas Gel-Patch, Zostrix Sports, Capsicum Oleoresin, Castiva Warming, Sloan's Liniment, Capzasin Back and Body, Trixaicin HP, Capsin