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Collegium Receives FDA Approval for Xtampza ER, an Analgesic with Abuse-Deterrent Properties

Posted 3 days ago by Drugs.com

CANTON, Mass., April 26, 2016 (GLOBE NEWSWIRE) – Collegium Pharmaceutical, Inc. (Nasdaq:COLL) today announced that the U.S. Food and Drug Administration (FDA) approved Xtampza ER (oxycodone) extended-release (ER) capsules CII, a twice-daily, oxycodone medication for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Xtampza ER is Collegium’s first product utilizing its proprietary DETERx® technology platform, and is designed to provide adequate pain control while maintaining its drug release profile after being subjected to common methods of manipulation including chewing and crushing the product prior to administration. The Xtampza ER label contains information supporting the administration of the product by sprinkling the capsule contents on soft foods or into a cup, and th ... Read more

Related support groups: Pain, Oxycodone, Narcotic, Pain Medication, Pain Management, Pain Relief, Pain Pill, Pain Killer, Opioid, Xtampza ER

Heat Beats Cold for Treating Jellyfish Stings

Posted 4 days ago by Drugs.com

FRIDAY, April 29, 2016 – If you're unlucky enough to suffer a jellyfish sting, new research says that heat is better than cold for easing the pain. The team at the University of Hawaii at Manoa noted that jellyfish stings are a growing health problem worldwide. But, there has been disagreement over how best to treat and manage the painful stings. "People think ice will help because jelly stings burn and ice is cold," study author Christie Wilcox, a postdoctoral fellow at the University of Hawaii's School of Medicine, said in a university news release. "And if you Google it, many sites – even those considered reputable – will tell you to put ice on a sting to dull the pain. But research to date has shown that all marine venoms are highly heat sensitive, thus hot water or hot packs should be more effective than cold packs or ice," she explained. In an attempt to resolve the ongoing ... Read more

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Freezing Technique May Ease 'Phantom Limb' Pain for Amputees

Posted 8 Apr 2016 by Drugs.com

FRIDAY, April 8, 2016 – A freezing technique may reduce the debilitating phantom limb pain that many amputees experience, according to a new, small study. Chronic pain that emanates from the site of a severed limb can be reduced in some cases when the remaining nerve and scar tissue is frozen in place, researchers said. The minimally invasive technique, known as cryoablation therapy, may offer hope to the roughly 200,000 Americans who undergo an amputation every year, according to U.S. Centers for Disease Control and Prevention statistics. Many such patients, including military veterans and people with diabetes, experience a crippling form of nervous system disorientation after losing a limb. The study authors said the problem stems from inaccurate signaling among the remaining limb nerve endings and/or overactivity among neighboring nerves. The result is a distinct feeling of limb ... Read more

Related support groups: Pain, Chronic Pain, Neuralgia, Neuropathic Pain, Meralgia Paresthetica

Sleepy Teens Are Risk-Taking Teens

Posted 7 Apr 2016 by Drugs.com

THURSDAY, April 7, 2016 – Sleep-deprived high school students are more likely to sustain injuries – often due to risky behaviors – than those who are well rested, U.S. health officials reported Thursday. In a study of more than 50,000 students, researchers found that those teens who got seven hours of sleep or less on school nights were more likely to engage in risky behaviors, such as not wearing a seatbelt, riding with a drinking driver, and drinking and driving. "The failure of most high school students to get sufficient sleep may put them at increased risk for unintentional injuries," said lead researcher Anne Wheaton, an epidemiologist at the U.S. Centers for Disease Control and Prevention. The study also found that teens who slept 10 or more hours a night were also prone to injuries and risky behaviors, compared with students who slept nine hours. "We have known all along that ... Read more

Related support groups: Pain, Depression, Sleep Disorders, Chronic Pain, Insomnia, Fatigue

Anti-Addiction Drug May Help Curb Painkiller, Heroin Dependence

Posted 31 Mar 2016 by Drugs.com

WEDNESDAY, March 30, 2016 – The newer anti-addiction drug naltrexone may become an important weapon in the country's escalating addiction to opioid painkillers and heroin, a new study suggests. Researchers found that monthly injections of extended-release naltrexone – which blocks the euphoric effects of opioids – resulted in a significantly lower relapse rate among treated addicts compared to a similar group that didn't receive the drug. Additionally, during the six-month study there were no overdoses in the naltrexone group compared to five in the other group. Opioids – including prescription painkillers such as OxyContin, Vicodin and Percocet, as well as the street drug heroin – killed more than 28,000 people in 2014, a record high, according to the U.S. Centers for Disease Control and Prevention. "We thought this was a good approach to relapse prevention . . . but I was ... Read more

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Obama Administration Steps Up Efforts to Beat Painkiller, Heroin Epidemic

Posted 29 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – The Obama administration announced Tuesday additional measures in its $1.1 billion funding request to expand medication-based treatment for Americans addicted to prescription painkillers and heroin. President Barack Obama is scheduled to propose the measures at the National Rx Drug Abuse & Heroin Summit in Atlanta. The White House said the increased initiative could offer hope to tens of thousands of Americans addicted to prescription painkillers, such as OxyContin, Vicodin and Percocet, as well as illegal drugs like heroin. "The President has made clear that addressing this epidemic is a priority for his Administration, and today's actions represent further steps to expand access to treatment, prevent overdose deaths and increase community prevention strategies," the White House said in a statement. Most of the funding requested from Congress would enable ... Read more

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Cancer Patients Who Choose to Die at Home Live Longer: Study

Posted 28 Mar 2016 by Drugs.com

MONDAY, March 28, 2016 – Cancer patients who chose to die at home lived longer than those who died in hospitals, a large study from Japan found. The findings suggest that doctors shouldn't hesitate to allow dying cancer patients to receive palliative care at home, the study authors said. Palliative care does not attempt to cure a person, but is often described as comfort care or symptom management. Most people would like to be at home when dying, but there have been concerns about whether the quality of care would be the same as in a hospital, the researchers pointed out. "The cancer patient and family tend to be concerned that the quality of medical treatment provided at home will be inferior to that given in a hospital and that survival might be shortened," said study author Dr. Jun Hamano, of the University of Tsukuba in Japan. "However, our finding – that home death does not ... Read more

Related support groups: Pain, Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Brain Tumor, Ovarian Cancer, Cervical Cancer, Stomach Cancer, Breast Cancer - Palliative, Testicular Cancer

Nearly All U.S. Doctors 'Overprescribe' Addictive Narcotic Painkillers: Survey

Posted 28 Mar 2016 by Drugs.com

FRIDAY, March 25, 2016 – When American doctors give their patients narcotic painkillers, 99 percent of them hand out prescriptions that exceed the federally recommended three-day dosage limit, new research suggests. And some doctors exceeded that limit by a lot: Nearly one-quarter gave out month-long dosages, despite the fact that research has shown that a month's use of prescription narcotic painkillers can cause brain changes, the National Safety Council survey found. "Opioids do not kill pain. They kill people," Dr. Donald Teater, a medical advisor at the safety council, said in a news release. "Doctors are well-intentioned and want to help their patients, but these findings are further proof that we need more education and training if we want to treat pain most effectively." The problem has reached the point where these highly addictive painkillers, which include commonly ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Methadone, Back Pain, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Chronic Pain, Norco, Fentanyl, Morphine, Lortab, Codeine, Opana, Subutex, Dilaudid, Opana ER

FDA Wants Generic Narcotic Painkillers to Be Abuse-Deterrent

Posted 24 Mar 2016 by Drugs.com

THURSDAY, March 24, 2016 – Continuing their push to combat the nation's epidemic of prescription painkiller abuse, U.S. officials on Thursday urged generic drug makers to take steps to redesign potent drugs such as hydrocodone and oxycodone to make them harder to abuse. U.S. Food and Drug Administration officials said they were encouraging the generic drug industry to develop pain medicines with "abuse-deterrent properties." For instance, this would make it harder to crush a tablet to snort the contents or dissolve a capsule to inject its ingredients. "By issuing the draft guidance, the FDA is helping to ensure that generic abuse-deterrent opioids are no less abuse deterrent than their brand-name counterparts," FDA Commissioner Dr. Robert Califf said during a morning press briefing. "We hope that the availability of less costly generic products with abuse-deterrent properties has the ... Read more

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FDA Medwatch Alert: Opioid Pain Medicines: Drug Safety Communication - New Safety Warnings Added to Prescription Opioid Medications

Posted 23 Mar 2016 by Drugs.com

ISSUE: FDA is warning about several safety issues with the entire class of opioid pain medicines. See the FDA Drug Safety Communication for a complete listing. These safety risks are potentially harmful interactions with numerous other medications, problems with the adrenal glands, and decreased sex hormone levels. We are requiring changes to the labels of all opioid drugs to warn about these risks. Opioids can interact with antidepressants and migraine medicines to cause a serious central nervous system reaction called serotonin syndrome, in which high levels of the chemical serotonin build up in the brain and cause toxicity (see List of Serotonergic Medicines in the FDA Drug Safety Communication). Cases of serotonin syndrome in the FDA Adverse Event Reporting System (FAERS) database were reported more frequently with the opioids fentanyl and methadone used at the recommended doses. T ... Read more

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FDA announces enhanced warnings for immediate-release opioid pain medications related to risks of misuse, abuse, addiction, overdose and death

Posted 22 Mar 2016 by Drugs.com

March 22, 2016 – In a continuing effort to educate prescribers and patients about the potential risks related to opioid use, the U.S. Food and Drug Administration today announced required class-wide safety labeling changes for immediate-release (IR) opioid pain medications. Among the changes, the FDA is requiring a new boxed warning about the serious risks of misuse, abuse, addiction, overdose and death. Today’s actions are among a number of steps the agency recently outlined in a plan to reassess its approach to opioid medications. The plan is focused on policies aimed at reversing the epidemic, while still providing patients in pain access to effective relief. The FDA is also requiring several additional safety labeling changes across all prescription opioid products to include additional information on the risk of these medications. This is part of the agency’s overall effort to hel ... Read more

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FDA Orders Warning Labels on Prescription Narcotic Painkillers

Posted 22 Mar 2016 by Drugs.com

TUESDAY, March 22, 2016 – Hoping to curb a national epidemic of prescription painkiller abuse, U.S. officials on Tuesday announced that certain drugs will get new "boxed warnings" about the dangers of misuse. The move by the U.S. Food and Drug Administration comes one week after the U.S. Centers for Disease Control and Prevention announced tough new guidelines to doctors for "opioid" drugs such as Oxycontin, Percocet and Vicodin. "We are at a time when the unfathomable tragedies resulting from addiction, overdose and death has become one of the most urgent, devastating public health crises facing our country," FDA Commissioner Dr. Robert Califf told reporters at a Tuesday news briefing. He said the agency is working with other agencies, drug makers, doctors and patients "to prevent abuse, save lives and treat dependence while still providing patients in pain access to effective ... Read more

Related support groups: Pain, Oxycodone, Back Pain, Hydrocodone, Percocet, OxyContin, Vicodin, Chronic Pain, Norco, Lortab, Breakthrough Pain, Roxicodone, Drug Dependence, Endocet, Acetaminophen/Hydrocodone, Vicoprofen, Percocet 10/325, Hydromet, Roxicet, Acetaminophen/Oxycodone

Acetaminophen Won't Help Arthritis Pain, Study Finds

Posted 18 Mar 2016 by Drugs.com

THURSDAY, March 17, 2016 – Acetaminophen – commonly known as Tylenol in the United States – isn't an effective choice for relieving osteoarthritis pain in the hip or knee, or for improving joint function, a new study finds. Although the drug rated slightly better than placebo in studies, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) or diclofenac are better choices for short-term pain relief, the researchers said. "Regardless of dose, the prescription drug diclofenac is the most effective drug among painkillers in terms of improving pain and function in osteoarthritis," said lead researcher Dr. Sven Trelle. He's co-director of clinical trials at the University of Bern in Switzerland. However, even diclofenac comes with side effects. "If you are thinking of using a painkiller for osteoarthritis, you should consider diclofenac," Trelle said, but also ... Read more

Related support groups: Pain, Percocet, Vicodin, Norco, Osteoarthritis, Lortab, Tylenol, Ibuprofen, Naproxen, Meloxicam, Advil, Acetaminophen, Diclofenac, Voltaren, Mobic, Aleve, Voltaren Gel, Motrin, Hip Replacement, Paracetamol

More Older Women Now Living With 'Moderate' Disability, Study Shows

Posted 18 Mar 2016 by Drugs.com

THURSDAY, March 17, 2016 – Back in the 1980s, older U.S. women typically lived more years free of disabilities than their male peers did, but a new study shows that pattern appears to be changing. For older men, the news is largely positive, researchers report: They're not only living longer, but with fewer disabilities. For women, the picture is different: They've made smaller gains than men have and, in some respects, they've taken a step backward. Specifically, older U.S. women were more likely to be living with moderate disabilities in 2011, compared with 2004 – a reversal in the improvement seen since 1982. The study defined moderate disabilities as problems with daily activities such as shopping, doing household chores or managing money. For men, the prevalence of those issues dropped between 1982 and 2004, then stayed largely unchanged. Older women, on the other hand, saw their ... Read more

Related support groups: Pain, Obesity, Chronic Pain, Cardiovascular Conditions and Disorders

Health Tip: Use Proper Lifting Technique

Posted 16 Mar 2016 by Drugs.com

-- Lifting heavy things without the proper technique is an easy way to hurt your back. To help prevent back injury and pain, the American Academy of Orthopaedic Surgeons advises: Plan before you lift, and don't rush. Standing near the object, place your feet shoulder-width apart. Bend at the knees. As you stand, use your leg muscles to lift. Ask someone for help if the object is too heavy or awkward. Read more

Related support groups: Pain, Back Pain, Chronic Pain, Sciatica, Scoliosis, Herniated Disc, Radiculopathy

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Anacin AF, Conacetol, Dolono, Tempra 3, Tempra 2, Panadol Childrens, Panadol Jr, Genebs, Genapap Extra Strength, Redutemp, St Joseph Aspirin-Free, Liquiprin, Actamin, Ed-APAP, Dolono Infant, Pain-Eze, Uniserts, Silapap Childrens, Feverall, Acephen, IBU-200, Menadol, Saleto-200, Saleto-400, Haltran, Ibu-Tab, Children's ElixSure, Indocin IV, Cafgesic, Saleto-600, Saleto-800, Motrin Junior Strength, Aflaxen, Orudis KT, Ibu-8, Ibu-4, Advil Childrens, Advil Junior Strength, Childrens Ibuprofen Berry, Adprin B, Tempra Quicklets, Umphamol, Remedol, Panamax 240, Paralgin, Panadol ActiFast, Miradol, Anadin Paracetamol, Hedex, Mandanol, Parahexal, Febridol, Duatrol SR, Mapap Meltaway, Mapap Arthritis Pain, Mandanol 6+, Mandanol Infant, Parmol, Silapap Infants, Cuprofen for Children, Paracets, Medinol Over 6, Junior Strength Tylenol, Infant's Tylenol, Elixsure Fever / Pain, Infadrops, Acetaminophen-odan, Atasol Forte, Bromo Seltzer, Tycolene, Atasol, Calpol Infant, Disprol Paracetamol, Alvedon, Calpol Fastmelts, Calpol Six Plus, Medinol Under 6, Medinol Paediatric, Galpamol, Paldesic, Calpol Paediatric, Myophen, Lagesic, lansoprazole / naproxen, magnesium salicylate / phenyltoloxamine, meclofenamate, morphine liposomal, ibuprofen / oxycodone, dyclonine, choline salicylate / magnesium salicylate, diphenhydramine / ibuprofen, diphenhydramine / magnesium salicylate, pentafluoropropane / tetrafluoroethane, rofecoxib, capsaicin / lidocaine / menthol / methyl salicylate, acetaminophen / magnesium salicylate, naloxone / oxycodone, bupivacaine liposome, capsaicin / menthol / methyl salicylate topical, tolmetin, aspirin / dextromethorphan / phenylephrine, morphine / naltrexone, camphor / menthol, benzocaine / dextromethorphan, acetaminophen / caffeine / phenyltoloxamine / salicylamide, acetaminophen / dextromethorphan, acetaminophen / dextromethorphan / doxylamine, acetaminophen / guaifenesin, acetaminophen / caffeine / phenyltoloxamine, acetaminophen / caffeine / magnesium salicylate / phenyltoloxamine, acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide, acetaminophen / aspirin, acetaminophen / aspirin / caffeine / salicylamide, acetaminophen / phenyltoloxamine / salicylamide, alfentanil, aspirin / diphenhydramine, aspirin / hydrocodone, aspirin / meprobamate, aspirin / codeine, aspirin / caffeine / salicylamide, aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide, aspirin / butalbital, aspirin / caffeine / dihydrocodeine, diphenhydramine / naproxen, acetaminophen / aspirin / diphenhydramine, Capital w/ Codeine, Medi-Seltzer, Farbital, Xylocaine Topical, Duraclon, EC-Naprosyn, Mapap Children's, Children's Silapap, Febrol Solution, Astramorph PF, Duramorph, P-A-C, Magsal, Myogesic, Hydrocet, Dolagesic, Buffasal, Synalgos-DC, Hycet, Tolectin 600, Tolectin DS, Tylophen, Genapap, Aceta w/ Codeine, Tylenol 8 Hour, Duraxin, Dolorex, capsaicin / lidocaine / menthol, camphor / menthol / tetracaine, capsaicin / diclofenac, Aspiritab, Sublimaze, Infumorph, Prevacid NapraPAC, Numorphan, LMX 5, Lidosense 5, Combunox, Indocin SR, Oruvail, Paraspen, Dymadon, Laryng-O-Jet Spray, Senatec, LTA Preattached 360 Kit, LTA Pediatric Kit, LMX 4, LMX 4 with Tegaderm, Ela-Max, Ela-Max 5, LMX Plus, LTA II Kit, Mosco Nail A Cain, Nuprin Backache Caplet, Vistazine, Tronothane, Mobidin, Magan, Outgro Pain Relief, Rid-A-Pain, Numorphan HCl, Protech First Aid Stik, Medi-Quik Spray, Rescudose, Morphine Rapi-Ject, Doloral, Doloral Sirop, Roxanol 100, Duramorph PF, Aspirin Lite Coat, Ionsys, Hydrostat IR, Morphitec, M-Oxy, Lidomar, Xylocaine 10% Oral, Dermaflex, Anestacon, PP-Cap, Percolone, ETH-Oxydose, Endocodone, Prax, Sarna Ultra, Empirin with Codeine, Zydone, Lorcet HD, Panacet, Tylenol with Codeine 2, Phenaphen with Codeine, Hyflex-DS, RhinoFlex 650, EZ III, Stagesic, Azdone, Percodan-Demi, Roxiprin, Mepergan Fortis, Percocet 7.5 / 500, Lortab ASA, Alor 5 / 500, Panasal 5 / 500, Damason-P, Hyflex-650, Alpain, Capsin, Capsicum Oleoresin, Zostrix Sports, Castiva Warming, Trixaicin HP, RT Capsin, Sucrets, Wild Cherry, Zostrix-HP, Dolorac, Major-gesic, Phenylgesic, Vitoxapap, Flextra-DS, Relagesic, Uni-Perr, Q-Gesic, Apagesic, Phenagesic, Genasec, YSP Aspirin, Zero-Order Release, Panadol Rapid Handipak, Panadol Soluble, Rex Paracetamol, Paineze Paracetamol, Benylin Sore Throat, Chem Mart Chemadol, Lemsip Headcold, Lemsip Original, Bydol, Panamol, Tempol, Dolko Enfants, Dolotec, Efferalgan, Dolko, Dolitabs, Taminol, Doliprane Adultes, Doliprane Sans Sucre, Accidental Rapatabs, Febridol Infant Drops, Priceline Paracetamol, Panadol Gel Caps, Pacimol Caplets, Pharmore Paracetamol, Paracare, Pharmacist Paracetamol, Promax, Panadol Gel Tabs, Panadol Mini Caps, Sigma Pain Relief, Pain Clear Paracetamol, Panadol Extend, Paracetamol Soluble, Sigma Paracetamol, Hexal Comfarol, Pharmaction Paracetamol, Setamol, Paraspen Drops, Panadol Colourfree Drops, Efferalgan Pediatrique, Efferalganodis, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Entercote, Ecotrin Maximum Strength, Empirin, Bayer Plus, Buffex, Litecoat Aspirin, Minitabs, Ascriptin Enteric, Norwich Aspirin, Acetylsalicylic Acid, Stanback Analgesic, Therapy Bayer, Tri-Buffered Aspirin, Entaprin, Bufferin Extra Strength, Halfprin, Alfenta, Paracetamol EG, Paracetamol Ivax, Paracetamol Merck, Paracetamol Biogaran, Paracetamol Arrow, Expandox, Geluprane, Paracetamol Almus, Paracetamol Qualimed, Paracetamol Ranbaxy, Mapap Rapid Tabs, Tolectin, Vanatrip, Paralyoc, Paracetamol Zydus, Paracetamol RPG, Paracetamol Sandoz, Paracetamol Winthrop, Wygesic