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Related terms: Acquired Immune Deficiency Syndrome, Acquired Immunodeficiency Syndrome (AIDS), Acute HIV Infection, Acute Retroviral Syndrome, AIDS, AIDS-Related Complex, Chronic Symptomatic HIV Infection, HIV Infection, Acute, HIV Seroconversion Syndrome, Human Immunodeficiency Virus Infection, Primary HIV Infection, HIV, ARC, Acquired Immunodeficiency Syndrome, HIV/AIDS

Needle-Exchange Program Curbed HIV Spread, Study Finds

Posted 1 day 4 hours ago by Drugs.com

THURSDAY, Sept. 3, 2015 – A needle-exchange program in Washington, D.C., has prevented hundreds of new HIV infections, a new study suggests. The program for injection drug users was launched in 2007, and it prevented an estimated 120 new cases of HIV infection and saved about $44 million in HIV treatment costs within two years, the researchers said. The findings were published online Sept. 3 in the journal AIDS and Behavior. "Our study adds to the evidence that needle-exchange programs not only work, but are cost-effective investments in the battle against HIV," Monica Ruiz, of George Washington University in Washington, D.C., said in a university news release. Ruiz is an assistant research professor in the department of prevention and community health at the university's Milken Institute School of Public Health. "We saw a 70 percent drop in newly diagnosed HIV cases in just two years. ... Read more

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Gains in Life Spans Seen Around the Globe

Posted 8 days ago by Drugs.com

THURSDAY, Aug. 27, 2015 – Average life expectancy among people worldwide has risen by more than six years since 1990, and healthy life expectancy has climbed by more than five years, a new report shows. The analysis of data from 188 countries found that life expectancy for both sexes increased from just over 65 years in 1990 to 71.5 years in 2013, while healthy life expectancy rose from almost 57 years to slightly more than 62 years. The findings regarding healthy life expectancy versus total life expectancy mean that people are living more years with illness and disability, according to the authors of the study published Aug. 27 in The Lancet. "The world has made great progress in health, but now the challenge is to invest in finding more effective ways of preventing or treating the major causes of illness and disability," study author Theo Vos, a professor at the Institute for Health ... Read more

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Only 1 in 5 Gay Teen Boys Get HIV Test

Posted 9 days ago by Drugs.com

WEDNESDAY, Aug. 26, 2015 – Gay teen boys are much less likely to get tested for HIV than older gay males, researchers report. The researchers surveyed more than 300 gay and bisexual male teens between the ages of 14 and 18 from across the United States. Only one in five had ever been tested for HIV, a rate significantly lower than among older gay and bisexual men, the researchers noted. For example, a 2008 U.S. Centers for Disease Control and Prevention-sponsored study of gay men found that 75 percent of those aged 18 to 19 had been tested for HIV. Major barriers to gay teens getting tested for HIV are not knowing where to go for a test, concerns about being recognized at a testing location, and believing they won't get infected, the Northwestern University researchers said. "Understanding the barriers to testing provides critical information for intervening, so we can help young men ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Diagnosis and Investigation

HIV Cells Keep Duplicating Even When Treatments Are Working: Study

Posted 6 Aug 2015 by Drugs.com

THURSDAY, Aug. 6, 2015 – HIV can continue to multiply in patients who are responding well to antiretroviral therapy, U.K. researchers say. Treatment advances over the last 30 years mean that HIV – the virus that causes AIDS – is suppressed to almost undetectable levels in many patients, and they can live a long and healthy life. It was believed that after many years of successful therapy, a patient's body would naturally rid itself of HIV. "This research shows that sadly, the HIV virus has found yet another way to escape our treatments," study leader Anna Maria Geretti, a professor from the University of Liverpool in the United Kingdom, said in a university news release. During treatment, the virus tries to avoid destruction by hiding in blood cells that trigger an immune response. HIV does this by integrating its own genetic information into the DNA of immune system cells called CD4 ... Read more

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Taking St. John's Wort for Depression Carries Risks: Study

Posted 29 Jul 2015 by Drugs.com

WEDNESDAY, July 29, 2015 – St. John's wort is a popular herbal therapy for depression, but a new Australian study highlights the fact that "natural" does not always equal "safe." Using reports filed with Australia's drug safety agency, the researchers found that adverse reactions to St. John's wort were similar to those reported for the antidepressant fluoxetine – better known by the brand name Prozac. Those side effects included anxiety, panic attacks, dizziness, nausea and spikes in blood pressure, the researchers reported in the July issue of Clinical and Experimental Pharmacology and Physiology. "It's concerning to see such severe adverse reactions in our population, when people believe they are doing something proactive for their health with little risk," lead researcher Claire Hoban, of the University of Adelaide, said in a university news release. Research has shown that St. ... Read more

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Test to Differentiate HIV Viruses Approved

Posted 24 Jul 2015 by Drugs.com

FRIDAY, July 24, 2015 – A new diagnostic to differentiate between strains of the AIDS-causing virus has been approved by the U.S. Food and Drug Administration. The Bio-Rad BioPlex 2200 HIV Ag-Ab assay can distinguish between HIV-1 and HIV-2, the FDA said in a news release. The diagnostic is approved for people aged two years and older, including pregnant women. The test can be used to screen organ donors for either strain of the HIV virus, but it's not been approved to routinely screen donated blood or plasma for the virus, the agency said. While cases of HIV-2 have been diagnosed in the United States, HIV-2 has been found primarily in West Africa, the FDA said. Most cases in the United States have been linked to HIV-1. The viruses are similar yet distinct. The new diagnostic is produced by Bio-Rad Laboratories, based in Hercules, Calif. More information Visit the FDA to learn more. Read more

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U.S. Teens Waiting Longer to Have Sex: CDC

Posted 22 Jul 2015 by Drugs.com

WEDNESDAY, July 22, 2015 – Less than half of U.S. teenagers aged 15 to 19 are having sex, a rate dramatically lower than it was a quarter-century ago, a new federal government report shows. Only 44 percent of girls and 47 percent of boys between the ages of 15 and 19 had sexual intercourse at least once from 2011 to 2013, the researchers found. That's down from 51 percent of girls and 60 percent of boys in 1988, said study author Gladys Martinez. She is a demographer/statistician with the National Center for Health Statistics (NCHS), part of the U.S. Centers for Disease Control and Prevention. The drop in teen sexual activity is most likely due to the AIDS epidemic and the cultural shift that resulted from increased awareness of sexually transmitted diseases, said Dr. Jill Rabin, co-chief of the division of ambulatory care & women's health programs-PCAP Services at North Shore-LIJ ... Read more

Related support groups: Birth Control, Contraception, HIV Infection, Sexually Transmitted Diseases

Genes May Be Key to a Better HIV Vaccine, Study Says

Posted 15 Jul 2015 by Drugs.com

WEDNESDAY, July 15, 2015 – Someone's genetic makeup may determine whether an HIV vaccine will work, a new study suggests. Scientists say the finding could help them find a way to immunize people against HIV, the virus that causes AIDS. While researchers have reported advances over the years, a working vaccine still seems far off. Genetics are "almost certainly" relevant to how well vaccines work, but "vaccine designers have so far sought a single vaccine for all, for the most part," said study co-author Daniel Geraghty, a scientist with the Fred Hutchinson Cancer Research Center in Seattle. "That approach isn't going to work for a lot of vaccines." In the new research, scientists analyzed results of a vaccine trial in Thailand that concluded in 2009. Over 42 months, the vaccine protected against HIV infection 31 percent of the time. The new analysis revealed that the vaccine was ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Diagnosis and Investigation, Vaccination and Prophlaxis

Many U.S. AIDS Patients Still Die When 'Opportunistic' Infections Strike

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – Even after the advent of powerful medications for suppressing HIV, a new study finds that more than one-third of people in San Francisco who were diagnosed with an AIDS-related infection died within five years. "The main cause of mortality arises from people stopping treatment entirely," said Dr. Robert Grant, a professor at the University of California, San Francisco, who reviewed the findings but was not involved in the research. When HIV treatment lapses, so-called "opportunistic" infections and illnesses can arise, posing a real threat to patients' health, he explained. The bottom line, according to Grant, is that there is still "a long way to go" in prolonging the lives of Americans with HIV/AIDS. The new study was led by Dr. Sandra Schwarcz, associate professor of epidemiology and biostatistics at the University of California, San Francisco. She and her ... Read more

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Sequence of Shots May Lead to Effective HIV Vaccine, Mouse Study Finds

Posted 25 Jun 2015 by Drugs.com

THURSDAY, June 25, 2015 – It's unlikely that a single vaccine would ever enable the body to neutralize the HIV virus, but a sequence of immunizations might hold the key, a new mouse study suggests. The immune system could be guided in a series of steps to develop a special type of HIV-fighting antibody, a team of researchers said. Each immunization would be customized for specific stages of the immune system's response to the virus. In the end, the series of shots would result in the production of broadly neutralizing antibodies capable of fighting HIV, the authors said. "As HIV mutates in a patient, the immune system continually adapts. In some patients, this process produces broadly neutralizing antibodies, which are unusual antibodies that can bind to and neutralize a wide range of globally occurring HIV variants. These are the antibodies we want to try to elicit with a vaccine," ... Read more

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Health Assistance to Developing Countries Up Since 1990: Study

Posted 16 Jun 2015 by Drugs.com

TUESDAY, June 16, 2015 – There has been an increase in health-related development assistance to low-income countries since 1990, a new study finds. The increased funding has focused mostly on HIV/AIDS, maternal health and newborn and child health. "Understanding how funding patterns have changed across time... may help identify where funding gaps persist and where cost-effective interventions could save lives," Joseph Dieleman, of the Institute for Health Metrics and Evaluation at the University of Washington in Seattle, and colleagues wrote. Even with increased assistance, a child's risk of dying before the age of 5 in a low-income country was 12 times higher than in the United States in 2013. A mother's risk of dying in childbirth was 21 times higher in a low-income country compared to the United States, the researchers noted. Most of these deaths are preventable, they added. ... Read more

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FDA Approves First Pediatric Lopinavir/Ritonavir Oral Pellets for the Treatment of AIDS in Infants and Young Children

Posted 9 Jun 2015 by Drugs.com

Mumbai, India - June 3, 2015 --Cipla Limited, a global pharmaceutical company which uses cutting edge technology and innovation to meet the everyday needs of all patients, today announced that it has received US FDA approval for an innovative formulation - Lopinavir/ritonavir (LPV/r) 40mg/10 mg oral pellets - for pediatric specific treatment for infants. Cipla has long recognized the lack of access to life saving child-friendly formulations for the treatment of HIV, which prompted it to develop an innovative formulation of LPV/r oral pellets. The pellets are to be sprinkled on sweetened porridge for infants and administered to them. The pellets are produced by melt-extrusion technology and are enclosed in capsules. Cipla has been working for many years in collaboration with Diana Gibb, Professor of Epidemiology, Senior Programme Leader and Honorary Consultant Pediatrician at ... Read more

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1 in 5 Younger Americans Tested for HIV

Posted 2 Jun 2015 by Drugs.com

TUESDAY, June 2, 2015 – Nearly one-fifth of teens and younger adults in the United States have been tested recently for HIV, federal health officials reported Tuesday. In 2011, more than 1 million Americans 13 and older had HIV, but one in seven did not know their infection status. Routine, voluntary testing is known to reduce transmission of HIV, the virus that causes AIDS, according to the U.S. Centers for Disease Control and Prevention. Researchers at the CDC's National Center for Health Statistics analyzed data from 5,600 females and more than 4,800 males, ages 15-44, who took part in the 2011-2013 National Survey of Family Growth. The researchers found that 19 percent had undergone HIV testing in the past year, an increase from 17 percent in both 2002 and 2006-2010. HIV testing rates in 2011-2013 were 22 percent for females and 16 percent for males, compared with 20 percent for ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Incivek, Pre-Exposure Prophylaxis, Truvada, Baraclude, Stribild, Victrelis, Complera, Tenofovir, Kaletra, Viread, Norvir, Entecavir, Triumeq, Telaprevir, Diagnosis and Investigation, Lamivudine, Ritonavir

Global Trial Finds HIV Drugs Should Be Taken Right After Diagnosis

Posted 28 May 2015 by Drugs.com

WEDNESDAY, May 27, 2015 – People with HIV should start taking medications to battle the virus that causes AIDS as soon as they're diagnosed, a new international study finds. Scientists involved in the trial were so impressed by the health benefits of early use of HIV drugs that they shut the study down early so they could offer the medications to all participants. The findings could alter World Health Organization guidelines about the best way to treat people with HIV, experts said. Currently, WHO recommends that HIV patients not start treatment until their immune system show signs of weakening. "We now have clear-cut proof that it is of significantly greater health benefit to an HIV-infected person to start antiretroviral therapy sooner rather than later," Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases, said in a statement. "Moreover, ... Read more

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Hundreds With HIV Could Donate Organs to Others With HIV: Study

Posted 14 May 2015 by Drugs.com

THURSDAY, May 14, 2015 – Nearly 400 HIV-positive potential organ donors in the United States could donate organs each year to HIV-positive people waiting for transplants, a new study estimates. "The findings are significant because there are not enough organ donors in the United States to meet the needs of all of the patients who might benefit from life-saving organ transplants," senior author Dr. Emily Blumberg, a professor in the infectious diseases division at the University of Pennsylvania's Perelman School of Medicine in Philadelphia, said in a university news release. "Some of the patients waiting for organs are infected with HIV but never make it to transplant because they either die while waiting or become too sick to be transplanted. HIV patients who undergo transplantation generally do well, so it is important to continue to look for ways to improve access to transplantation ... Read more

Related support groups: HIV Infection, Organ Transplant

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