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Certain Antipsychotics Up Risk of Death for Patients With Dementia: Study
Posted 23 Feb 2012 by Drugs.com
THURSDAY, Feb. 23 Compared to other antipsychotic drugs, haloperidol (Haldol) raises the risk of death in elderly patients with dementia, a new study finds. One outside expert believes the finding should aid in dementia care. "This data provides much-needed guidance and reassurance for the ever-increasing number of health care practitioners treating older demented patients," said Dr. Gisele Wolf-Klein, director of geriatric education at the North Shore-LIJ Health System in New Hyde Park, N.Y. The study was published online Feb. 23 in the British Medical Journal. In 2005, the U.S. Food and Drug Administration warned that certain antipsychotic drugs are associated with an increased risk of death in elderly patients with dementia. This warning was expanded to include conventional antipsychotics in 2008, according to a journal news release. The authors of the new study said that, despite ... Read more
Related support groups: Seroquel, Abilify, Geodon, Zyprexa, Risperdal, Seroquel XR, Risperidone, Dementia, Haldol, Quetiapine, Haloperidol, Olanzapine, Zyprexa Zydis, Aripiprazole, Haldol Decanoate
Antipsychotics Best for Controlling Mania: Study
Posted 16 Aug 2011 by Drugs.com
TUESDAY, Aug. 16 – The manic episodes experienced by those with bipolar disorder are better controlled by antipsychotic drugs than mood stabilizers, a new, large study suggests. Researchers from Italy and the United Kingdom also found that three antipsychotics – first-generation haloperidol (Haldol) along with later formulations of risperidone (Risperdal) and olanzapine (Zyprexa) – outperformed 11 other drugs. The scientists analyzed results from 68 randomized, controlled trials with more than 16,000 participants over a 30-year period. Mania typically alternates with depression in those with bipolar disorder, which tends to run in families and begin between the ages of 15 and 25, according to the U.S. National Institutes of Health. Acute manic episodes – characterized by hyperactivity, racing thoughts and reckless behavior – are not experienced by all bipolar patients, but severe ... Read more
Related support groups: Bipolar Disorder, Seroquel, Abilify, Mania, Geodon, Zyprexa, Risperdal, Seroquel XR, Saphris, Risperidone, Haldol, Latuda, Quetiapine, Haloperidol, Invega
Schizophrenia Drugs May Spur Subtle Brain Tissue Loss
Posted 10 Feb 2011 by Drugs.com
MONDAY, Feb. 7 – The use of antipsychotic drugs to treat schizophrenia is associated with the loss of a small but measurable amount of brain tissue, a new study finds. It included 211 schizophrenia patients who each underwent an average of three MRI brain scans over 7.2 years, for a total of 674 scans in the study group. The researchers then examined how four factors affected changes in brain volume over time: illness duration, illness severity, substance abuse and treatment with antipsychotic drugs. Longer duration of illness and antipsychotic treatment were both associated with loss of brain tissue. Higher doses of antipsychotics were associated with overall brain tissue loss, reduced gray matter and progressive declines in white matter. Illness severity and substance abuse had little or no association with brain tissue changes, according to the study, published in the February issue ... Read more
Related support groups: Seroquel, Abilify, Lithium, Geodon, Zyprexa, Schizophrenia, Risperdal, Seroquel XR, Saphris, Risperidone, Haldol, Quetiapine, Compazine, Haloperidol, Clozapine
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