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Related terms: Noninsulin-dependent Diabetes, Type 2 Diabetes, Diabetes, Type 2

FDA Medwatch Alert: DPP-4 Inhibitors for Type 2 Diabetes: Drug Safety Communication - May Cause Severe Joint Pain

Posted 8 hours ago by Drugs.com

ISSUE: The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines sitagliptin, saxagliptin, linagliptin, and alogliptin may cause joint pain that can be severe and disabling. FDA has added a new Warning and Precaution about this risk to the labels of all medicines in this drug class, called dipeptidyl peptidase-4 (DPP-4) inhibitors. See the Drug Safety Communication for a complete list of all FDA-approved DPP-4 inhibitors. BACKGROUND: DPP-4 inhibitors are used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. When untreated, type 2 diabetes can lead to serious problems, including blindness, nerve and kidney damage, and heart disease. These medicines are available as single-ingredient products and in combination with other diabetes medicines such as metformin. RECOMMENDATION: Patients should not stop taking their DPP-4 ... Read more

Related support groups: Diabetes, Type 2, Januvia, Janumet, Onglyza, Tradjenta, Sitagliptin, Janumet XR, Jentadueto, Linagliptin, Oseni, Kombiglyze XR, Saxagliptin, Alogliptin/pioglitazone, Kazano, Metformin/Sitagliptin, Alogliptin, Nesina, Juvisync, Empagliflozin/linagliptin, Simvastatin/sitagliptin

Antibiotics Linked to Type 2 Diabetes Risk

Posted 1 day 11 hours ago by Drugs.com

THURSDAY, Aug. 27, 2015 – Taking antibiotics might increase the risk of developing type 2 diabetes, new research suggests. Danish researchers found that people with type 2 diabetes tended to take more antibiotics in the years leading up to their diagnosis than Danes without the condition. "Patients with type 2 diabetes are overexposed to antibiotics compared with matched control persons without diabetes," said study researcher Dr. Kristian Hallundbaek Mikkelsen, a medical-doctoral student at the Center for Diabetes Research at Gentofte Hospital and the University of Copenhagen. "The overexposure is seen after, as well as 15 years, before the diagnosis of type 2 diabetes," Mikkelsen said. Although the researchers uncovered an association between antibiotic use and type 2 diabetes, it's important to note they did not establish a direct cause-and-effect relationship. For the study, the ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Penicillin VK, Penicillin V Potassium, Pen-Vee K, Truxcillin VK, Veetids, Beepen-VK, Pen-V, V-Cillin K, A-Cillin, Ledercillin VK

Even Short Bouts of Activity May Help Kids' Health

Posted 1 day 11 hours ago by Drugs.com

THURSDAY, Aug. 27, 2015 – Even brief spurts of exercise may benefit children, researchers report. Their study of 28 healthy, normal-weight children found that doing three minutes of moderate-intensity walking every half hour over three hours of sitting led to lower levels of blood sugar and insulin, compared to another day when the children sat for three hours straight. On the day the children took brief walks, they did not eat any more at lunch than on the day they remained seated for the entire three hours, according to the study published online Aug. 27 in the Journal of Clinical Endocrinology and Metabolism. The findings suggest that brief bouts of activity during otherwise inactive periods could help protect children against type 2 diabetes, heart disease and cancer, the U.S. National Institutes of Health researchers said. "We know that 30 minutes or more of moderate physical ... Read more

Related support groups: Obesity, Diabetes, Type 2, Weight Loss, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Abnormal Glucose Tolerance

Gains in Life Spans Seen Around the Globe

Posted 1 day 11 hours ago by Drugs.com

THURSDAY, Aug. 27, 2015 – Average life expectancy among people worldwide has risen by more than six years since 1990, and healthy life expectancy has climbed by more than five years, a new report shows. The analysis of data from 188 countries found that life expectancy for both sexes increased from just over 65 years in 1990 to 71.5 years in 2013, while healthy life expectancy rose from almost 57 years to slightly more than 62 years. The findings regarding healthy life expectancy versus total life expectancy mean that people are living more years with illness and disability, according to the authors of the study published Aug. 27 in The Lancet. "The world has made great progress in health, but now the challenge is to invest in finding more effective ways of preventing or treating the major causes of illness and disability," study author Theo Vos, a professor at the Institute for Health ... Read more

Related support groups: Back Pain, Diabetes, Type 2, Heart Disease, Chronic Obstructive Pulmonary Disease, Ischemic Stroke, HIV Infection, Malaria, Respiratory Tract Disease, Ischemic Heart Disease

Oldest Sister at Greater Risk of Obesity, Study Contends

Posted 1 day 11 hours ago by Drugs.com

WEDNESDAY, Aug. 26, 2015 – Firstborn girls are more likely to be overweight or obese in adulthood than their younger sisters, results of a new study suggest. Firstborns had 29 percent greater odds of being overweight and 40 percent greater odds of being obese than sisters born second, the researchers said. In addition, firstborns were also slightly taller. "This is the fourth study we have done to characterize the health risks of firstborn in four different populations," said lead researcher Dr. Wayne Cutfield, a professor of pediatric endocrinology at the Liggins Institute of the University of Auckland in New Zealand. "If you look at the health risks of those that are firstborn, you find that firstborns are more insulin resistant than later borns, which is a risk factor for diabetes, and they have higher blood pressure than later borns," he said. However, the new study is an ... Read more

Related support groups: High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension

Progress Slows Against Heart Disease Deaths for Adults Under 55, Study Shows

Posted 4 days ago by Drugs.com

MONDAY, Aug. 24, 2015 – There has been a sharp drop in heart disease death rates among Americans 65 and older in recent decades, but declines in death rates are slowing in those younger than 55, particularly women, a new study says. The findings appear Aug. 24 in the journal Circulation. "We think that these trends are not related to differences in treatment and hospitalization, but rather to a lack of effective preventive strategies for young people, particularly women," senior author Dr. Viola Vaccarino, professor and chair of epidemiology at Emory University's Rollins School of Public Health, said in a news release from the journal. One expert cardiologist agreed. "This is a true wake-up call – as much as progress is being made, we are falling behind in a group of young women who should be aggressively treated, managed and where prevention is essential," said Dr. Suzanne Steinbaum, ... Read more

Related support groups: Obesity, Diabetes, Type 2, Heart Disease

Exercise Best Bet Against Diabetes for College Graduates

Posted 4 days ago by Drugs.com

MONDAY, Aug. 24, 2015 – Exercise is more likely to help prevent diabetes in college graduates than in those with less schooling, a new study finds. Researchers examined data from the U.S. National Health and Nutrition Examination Survey 2007-2012, and found adults with a college degree who were physically active were 6 percent less likely to have pre-diabetic symptoms or elevated blood sugar levels than those who weren't active. For adults who only had some college, a high school diploma or who never finished high school, being physically active reduced the risk of pre-diabetic symptoms by just 1 percent. Overall, being physically active reduced the risk for full-blown diabetes, but this, too, varied by education level. The likelihood of having diabetes was 2.5 percent among college graduates who were physically active and 4.4 percent among those who were inactive. Rates among adults ... Read more

Related support groups: Obesity, Diabetes, Type 2, Weight Loss, Pre-Diabetes, Diabetes Mellitus, Abnormal Glucose Tolerance

9 Factors You Can Control May Be Key to Alzheimer's Risk

Posted 7 days ago by Drugs.com

THURSDAY, Aug. 20, 2015 – Up to two-thirds of Alzheimer's cases worldwide may stem from any of nine conditions that often result from lifestyle choices, a broad research review suggests. Those include obesity (specifically, high body mass index, an indication of obesity, in midlife); carotid artery disease, in which plaque buildup narrows major neck arteries and slows blood supply to the brain; high blood pressure; depression; being frail; being poorly educated; having high levels of a naturally occurring amino acid known as homocysteine; and (specifically among those of Asian descent) being a smoker and/or having either type 2 diabetes. The implication: Taking steps to minimize or eliminate such conditions might reduce the long-term risk for developing Alzheimer's, a brain disorder that affects memory and thinking. It is the most common form of dementia among seniors. "The current ... Read more

Related support groups: Depression, High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension, Smoking, Major Depressive Disorder, Alzheimer's Disease, Dysthymia, Coronary Artery Disease (CAD), Hypertensive Heart Disease

Diabetes Drug Might Also Help Some Patients Lose Weight

Posted 10 days ago by Drugs.com

TUESDAY, Aug. 18, 2015 – High doses of the diabetes drug liraglutide (Victoza) seem to help patients with type 2 diabetes lose weight, a new study suggests. In a trial funded by the drug's maker Novo Nordisk, people who took 3 milligrams (mg) of Victoza daily over 56 weeks lost an average of 6 percent of their body weight (14 pounds). According to Dr. Joel Zonszein, director of the Clinical Diabetes Center at Montefiore Medical Center in New York City, the U.S. Food and Drug Administration has approved the 3 mg-dose for weight loss, but not to treat diabetes. Only lower doses, either 1.2 mg or 1.8 mg a day, have the agency's blessing for treating type 2 diabetes. "This is the first study specifically designed to investigate the efficacy of liraglutide for weight management in patients with type 2 diabetes at a dose of 3 mg, and not surprisingly was found to be effective and tolerated ... Read more

Related support groups: Obesity, Diabetes, Type 2, Weight Loss, Victoza, Liraglutide, Saxenda

Neglecting Teen Health May Lead to Bigger Problems as Adults

Posted 11 days ago by Drugs.com

MONDAY, Aug. 17, 2015 – Nearly one in five teens has specific health care needs that are not receiving attention, and this may set them up for poorer physical and mental health in adulthood, a new study contends. "Previous research had shown that lack of medical care in this age group is associated with poor health and higher risk behaviors at the time. But, it wasn't known that these poor health outcomes persisted into adulthood," said lead author Dr. Dougal Hargreaves, a pediatrician and health services researcher at University College London, England, and at Boston Children's Hospital. The study was published online Aug. 17 in the journal Pediatrics. The researchers analyzed data from 14,800 participants in a long-term U.S. study of teen and adult health. The teens first answered questions in 1994-1995 when they were, on average, 16 years old. Then they responded in another ... Read more

Related support groups: Depression, Obesity, Diabetes, Type 2, Acne, Asthma, Asthma - Maintenance, Asthma - Acute, Allergic Asthma, Vaccination and Prophlaxis

Type 2 Diabetes Linked to Language Problems in Women

Posted 15 days ago by Drugs.com

THURSDAY, Aug. 13, 2015 – Insulin resistance, a key component of type 2 diabetes, may contribute to language problems in women that can potentially signal early dementia, new research suggests. The association was not seen in men, although the researchers could not determine exactly why that was so. In the study, the Finnish researchers measured what is called low verbal fluency, which is the rate at which you produce words. "Preclinical Alzheimer's disease typically starts with episodic memory decline. However, verbal fluency is a measure of executive function, and also deficits in executive function can be found early in the disease," said study author Dr. Laura Ekblad, a researcher at the University of Turku. Executive function includes higher-order processes such as working memory, planning and problem solving. But Ekblad added that the findings aren't cause for immediate concern ... Read more

Related support groups: Diabetes, Type 2, Insulin, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Could Your Smartphone Help Boost Your Heart Health?

Posted 15 days ago by Drugs.com

THURSDAY, Aug. 13, 2015 – Smartphones could become a high-tech tool to help boost heart health, experts say. The apps and wearable sensors on many cellphones can track exercise, activity and heart rates, and while evidence of their effectiveness in reducing risk factors for heart disease and stroke is limited, they could prove useful, a new American Heart Association scientific statement said. Currently, 20 percent of American adults use some type of technology to track their health data. The most popular health apps are associated with exercise, counting steps or tracking your heart rate, the heart association said. The authors of the statement reviewed the small number of published, peer-reviewed studies about the effectiveness of mobile health technologies in managing weight, boosting physical activity, quitting smoking, and controlling high blood pressure, high cholesterol and ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Hypertension, Heart Disease, Pre-Diabetes, Cardiovascular Risk Reduction, Hypertensive Heart Disease

Screen Teens With Depression for Heart Disease, Experts Say

Posted 17 days ago by Drugs.com

TUESDAY, Aug. 11, 2015 – Teens with major depression or bipolar disorder may face a higher risk for heart disease and they need to be followed closely, new recommendations from the American Heart Association state. "Youth with mood disorders are not yet widely recognized as a group at increased risk for excessive and early heart disease. We hope these guidelines will spur action from patients, families and health care providers to reduce the risk of cardiovascular disease among these youth," Dr. Benjamin Goldstein, a child-adolescent psychiatrist at Sunnybrook Health Sciences Center at the University of Toronto, said in a heart association news release. Goldstein and his colleagues reviewed published studies and found that teens with major depression or bipolar disorder were more likely than other teens to have: high blood pressure; high cholesterol; obesity, especially around the ... Read more

Related support groups: Depression, Bipolar Disorder, High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension, Smoking, Heart Disease, Major Depressive Disorder, High Cholesterol, Angina, Dysthymia, Cardiovascular Risk Reduction, Ischemic Heart Disease

Health Tip: Diabetes Can Take a Toll on Teeth and Mouth

Posted 18 days ago by Drugs.com

-- Diabetes, especially when uncontrolled, can cause damage to your mouth and teeth. The Mouthhealthy.org website says possible effects of diabetes on the teeth and mouth include: Dry mouth, due to decreased saliva production. Increased risk of cavities due to less saliva. Gingivitis, characterized by bleeding, inflamed gums. Difficulty tasting food. Slower healing of mouth wounds. Increased risk of infection. Among diabetic children. teeth emerging earlier than expected. Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Oral and Dental Conditions, Victoza, Xerostomia, Lantus, Januvia, Diabetes, Type 1, Glucophage, Toothache, Glipizide, Novolog, Humalog, Burning Mouth Syndrome, Diabetic Neuropathy, Janumet, Byetta, Bydureon, Glyburide

Skipping Breakfast a Bad Idea for People with Type 2 Diabetes

Posted 7 Aug 2015 by Drugs.com

FRIDAY, Aug. 7, 2015 – Running out the door without eating breakfast isn't a good idea for anyone, but new research suggests that for people with type 2 diabetes, skipping the morning meal may wreak havoc on blood sugar levels for the rest of the day. In a small clinical trial, researchers found that when people with diabetes skipped breakfast, their lunchtime blood sugar levels were 37 percent higher than on a day they ate breakfast. And blood sugar levels were still higher at dinnertime on the day the study volunteers skipped breakfast – 27 percent higher, the study said. "This is of high relevance since skipping breakfast has progressively increased over the past decades in Western society," said the study's lead author, Dr. Daniela Jakubowicz, a professor of medicine at Tel Aviv University in Israel. What's more, she said, high blood sugar levels after meals are strongly ... Read more

Related support groups: Diabetes, Type 2, Pre-Diabetes, Abnormal Glucose Tolerance

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