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Related terms: Noninsulin-dependent Diabetes, Type 2 Diabetes, Diabetes, Type 2

FDA Medwatch Alert: Olmesartan: Drug Safety Communication - FDA Review Finds Cardiovascular Risks for Diabetics Not Conclusive

Posted 24 Jun 2014 by Drugs.com

Includes: Benicar, Benicar HCT, Azor, Tribenzor, and Generics [Posted 06/24/2014] ISSUE: FDA has completed its safety review and has found no clear evidence of increased cardiovascular risks associated with use of the blood pressure medication olmesartan in diabetic patients (see previous alerts linked below). FDA believes the benefits of olmesartan in patients with high blood pressure continue to outweigh the potential risks. BACKGROUND: FDA safety review was prompted by the results of the ROADMAP trial. The ROADMAP (Randomized Olmesartan and Diabetes Microalbuminuria Prevention) clinical trial examined the effects of olmesartan in patients with type 2 diabetes, to see whether olmesartan could delay kidney damage. There was an unexpected finding of increased risk of cardiovascular death in the olmesartan group compared to the group taking a placebo, or sugar pill. However, the risk ... Read more

Related support groups: Diabetes, Type 2, Benicar, Azor, Benicar HCT, Olmesartan, Tribenzor, Amlodipine/hydrochlorothiazide/olmesartan, Hydrochlorothiazide/Olmesartan, Amlodipine/Olmesartan

Gut Microbes Differ in Obese or Diabetic People, Study Finds

Posted 23 Jun 2014 by Drugs.com

MONDAY, June 23, 2014 – Obese people and those with type 2 diabetes have lower levels of common types of "good" intestinal bacteria than healthy people, a new study reveals. The findings may be important, because measuring populations of these bacteria and other microscopic organisms in the intestines could help spot people at risk for obesity and diabetes, or the bacteria might offer targets for treating these conditions, the researchers said. The study was presented Sunday at the annual joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago. "Further studies should be carried out to elucidate if the gut microbial changes are a cause or effect of metabolic diseases," study lead investigator Dr. Yalcin Basaran, an endocrinologist from Gulhane Military Medical Academy School of Medicine in Ankara, Turkey, said in a meeting news release. ... Read more

Related support groups: Obesity, Diabetes, Type 2

People With Heart Disease, Diabetes May Be More Likely to Stay on Statins

Posted 23 Jun 2014 by Drugs.com

MONDAY, June 23, 2014 – People who have heart disease or diabetes, the overweight or obese and former smokers are most likely to keep taking cholesterol-lowering statins, a new study finds. Previous research has shown that as many 46 percent of patients who are prescribed statins stop taking them. Nearly one in 10 cardiovascular events are linked to failure to take prescribed drugs, according to background information in the study. Researchers looked at a group of people from Finland who began taking statins between 1998 and 2010. The people most likely to stop taking statins were women, single people and those aged 24 to 50. People without heart disease or diabetes were less likely to continue taking statins than those with the conditions. Among patients without heart disease or diabetes, those who were most likely to continue taking statins were overweight/obese or former smokers. ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Baycol, Pitavastatin, Altoprev

Health Tip: Helping Somone With Diabetes

Posted 23 Jun 2014 by Drugs.com

-- A friend or loved one who is struggling to manage diabetes may appreciate your help in achieving his or her goals. The National Diabetes Education Program suggests how to offer help to a friend or loved one with the disease: Ask the person if he or she ever feels sad or overwhelmed about having diabetes. Ask if the person has established goals to help control diabetes. Ask what may be interfering with managing diabetes well. Ask what you can do to help. Ask if the person has talked to a healthcare team about achieving goals and solving problems. Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1

Diabetes Distress Is Distinct From Depression, Researchers Say

Posted 16 Jun 2014 by Drugs.com

MONDAY, June 16, 2014 – Although diabetes distress is often mistaken for depression, the good news is that simple interventions appear to help significantly reduce this distress, according to new research. The need to correctly identify depression is also highlighted in a second new study. This concluded that people with type 1 diabetes who are also depressed have a higher risk of dying early compared to those who aren't depressed. Both studies were scheduled for presentation this week at the American Diabetes Association's annual meeting in San Francisco. Because the research hasn't been published in a peer-reviewed medical journal, it should be considered preliminary. "We're trying to make a distinction between diabetes distress and depression. Having some level of distress is part of the spectrum of diabetes," said the author of the first study, Lawrence Fisher, a professor of ... Read more

Related support groups: Depression, Diabetes, Type 2

Blacks May Respond Better Than Whites to Diabetes Drug Metformin

Posted 12 Jun 2014 by Drugs.com

THURSDAY, June 12, 2014 – Blacks with type 2 diabetes may fare better on the widely used drug metformin compared with whites, a new study finds. Researchers analyzed data from more than 19,600 Americans who were prescribed metformin between 1997 and 2013. The team found that blacks had greater improvements in their blood sugar control than whites. Study participants underwent at least two A1C blood tests at least four months apart while they took metformin. An A1C test measures a person's average blood sugar level over the previous three months. The maximum dose of metformin was associated with a 0.9 percent decrease in A1C results among blacks, compared with a 0.42 percent decrease among whites – a significant improvement. The study is published online June 12 in the Journal of Clinical Endocrinology & Metabolism. "Metformin is normally the first treatment physicians prescribe for ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet

Weight-Loss Surgery May Ease Type 2 Diabetes Long-Term

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – New research finds that weight-loss surgery is more helpful to obese patients with type 2 diabetes over the long term than regular care is. "This important study demonstrates what many of us in weight-loss surgery have suspected for years: That for those who are suffering from diabetes and severe obesity, weight-loss surgery and a healthy lifestyle works better to control these diseases than medical care alone," said Dr James McGinty, chief of the division of minimally invasive and baratric surgery at Mount Sinai St. Luke's and Mount Sinai Roosevelt Hospitals, in New York City. He was not involved in the new research. As obesity rates in the United States continue to rise, so do rates of obesity-linked type 2 diabetes. For years, improved diet, lifestyle changes and certain weight-loss medications were thought to be the only way to help obese diabetics slim ... Read more

Related support groups: Diabetes, Type 2, Gastric Bypass Surgery

Gene May Boost Chances of Type 2 Diabetes for Latinos

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – A new study links a gene variant found in Latinos to a fivefold increase in the risk of type 2 diabetes, potentially explaining why the condition is especially common in Latino people. In Mexico, for instance, an estimated 14 percent of adults had type 2 diabetes in 2006. The condition is also common among Latino people worldwide. In the new study, researchers studied DNA samples from almost 3,800 Latinos – including Latinos from the United States and Mexicans – who were recruited from 1993 to 2013. Of the participants, about 1,800 had type 2 diabetes and the rest, nearly 2,000 people, did not. One type of DNA found from this group was further tested in a group of more than 14,000 people. This rare genetic variant was found in slightly over 2 percent of those with type 2 diabetes and just 0.36 percent of those without diabetes. That means that the gene was ... Read more

Related support groups: Diabetes, Type 2

Insulin-Metformin Combo Tied to Poorer Survival in Diabetes Study

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – The combination of metformin and insulin for people with type 2 diabetes may slightly increase death rates among patients, according to researchers from Vanderbilt University. However, other experts question the study's conclusions and claim it is at odds with other better-designed studies that show the combination of metformin and insulin is both safe and effective. "Insulin remains a reasonable option for patients who have very high glucose [blood sugar] or who desire flexible and fast blood sugar control, but most patients taking metformin prefer to delay starting insulin," said lead researcher Dr. Christianne Roumie, an associate professor of internal medicine and pediatrics at Vanderbilt University in Nashville, Tenn. "The current study suggests that adding a sulfonylurea to metformin should be preferred to adding insulin for most patients who need a ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet

U.S. Diabetes Rate Jumps to 29 Million: CDC

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – The number of Americans with diabetes rose from 26 million in 2010 to 29 million – 9 percent of the population – in 2012, a new federal government study finds. One in every four people with diabetes does not even realize it, according to the report from the U.S. Centers for Disease Control and Prevention. Another 86 million American adults – more than one-third of adults – have what doctors call "prediabetes. " This means their blood sugar levels are higher than normal but not yet high enough to be classified as type 2 diabetes, the CDC said. Rates of prediabetes are similar for blacks (39 percent), Hispanics (38 percent) and whites (35 percent). "These new numbers are alarming, and underscore the need for an increased focus on reducing the burden of diabetes in our country," Ann Albright, director of CDC's Division of Diabetes Translation, said in an ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Pre-Diabetes, Diabetes Mellitus

Sleep Apnea May Raise Risk of Diabetes, Research Suggests

Posted 10 Jun 2014 by Drugs.com

FRIDAY, June 6, 2014 – A study of more than 8,600 people suffering from sleep apnea suggests a possible increased risk for developing diabetes, Canadian researchers report. They noted that sleep apnea results in less oxygen reaching cells in the body, less sleep and an increased heart rate, all of which are associated with a biological link to diabetes. "Controlling for known risk factors for diabetes – including age, sex, weight, smoking, other medical problems and income status – patients with severe sleep apnea had a 30 percent higher risk of developing diabetes than those without sleep apnea," said lead researcher Dr. Tetyana Kendzerska. She's with the University of Toronto's Institute of Health Policy, Management and Evaluation. Obesity, an important risk factor or both diabetes and sleep apnea, was taken into account. "We controlled for body-mass index [a measure of weight and ... Read more

Related support groups: Diabetes, Type 2, Sleep Apnea

For Obese Diabetics, Weight-Loss Surgery May Work Best

Posted 4 Jun 2014 by Drugs.com

WEDNESDAY, June 4, 2014 – Compared to diet and lifestyle changes, gastric bypass surgery appears to be the clear winner in helping obese people with type 2 diabetes lose weight and even rid themselves of the disease, new studies show. The findings "further confirm that gastric bypass is the most effective way of treating type 2 diabetes in obese patients, and that surgery is superior to medical treatment for the disease in terms of blood sugar control," said Dr. Subhash Kini, a bariatric surgeon and associate professor of surgery at the Icahn School of Medicine and The Mount Sinai Hospital, in New York City. He was not involved in the two new studies. The findings were published June 4 in JAMA Surgery. As obesity rates in the United States continue to rise, so do rates of obesity-linked type 2 diabetes. For years, improved diet, lifestyle changes and certain weight-loss medications ... Read more

Related support groups: Obesity, Diabetes, Type 2

1 in 10 Heart Attack Patients May Have Undiagnosed Diabetes

Posted 3 Jun 2014 by Drugs.com

TUESDAY, June 3, 2014 – As many as one in 10 Americans who has a heart attack may also have undiagnosed diabetes, a new study finds. "Diagnosing diabetes in patients who have had a heart attack is important because of the role diabetes plays in heart disease," lead author Dr. Suzanne Arnold, assistant professor at Saint Luke's Mid America Heart Institute and the University of Missouri at Kansas City, said in an American Heart Association (AHA) news release. "By recognizing and treating diabetes early, we may be able to prevent additional cardiovascular complications through diet, weight loss and lifestyle changes, in addition to taking medications. Another important reason to diagnose diabetes at the time of heart attack is that it can guide the treatments for the patient's coronary artery disease," she explained. For the study, researchers analyzed data from more than 2,800 heart ... Read more

Related support groups: Diabetes, Type 2, Heart Attack, Myocardial Infarction

Diabetics Fare Worse After Heart Surgery, Study Finds

Posted 29 May 2014 by Drugs.com

THURSDAY, May 29, 2014 – People with diabetes have an increased risk of problems after heart bypass surgery, a new study finds. Researchers looked at more than 9,200 patients in China who underwent coronary artery bypass graft surgery (CABG) between 1999 and 2008, and found that those with diabetes had worse outcomes after two years than those without the condition. Costs were also higher among patients with diabetes, according to the study in the June issue of the Annals of Thoracic Surgery. These expenses were mainly due to additional hospitalizations and medical procedures, and the use of insulin and other medications. "Based on the results of our study, we highly recommend an individualized treatment plan and a heart team approach for patients with diabetes who require CABG surgery," lead author Dr. Heng Zhang, of Fuwai Hospital in China, said in a journal news release. "We also ... Read more

Related support groups: Surgery, Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Diabetes May Be Bigger Threat to the Female Heart: Study

Posted 25 May 2014 by Drugs.com

THURSDAY, May 22, 2014 – Diabetes appears to pose a greater risk to heart health for women than men, a new analysis of current research contends. "The risk of coronary heart disease conferred by diabetes is between 40 percent to 50 percent greater for women than for men," said study co-author Rachel Huxley, director of the Queensland Clinical Trials and Biostatistics Centre at the University of Queensland in Australia. The results support findings from an earlier analysis that found that women with diabetes have a nearly 50 percent increased risk of death from heart disease compared to men with diabetes, the study authors said. This difference could stem from the fact that men develop full-blown type 2 diabetes earlier than women and at a lower weight, Huxley said. Because of this, men receive aggressive treatment sooner both for their diabetes and potential heart health risks, such as ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

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