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Weight Loss May Help Thwart Diabetes

Posted 19 Jul 2013 by Drugs.com

FRIDAY, July 19 – Overweight people with pre-diabetes can reduce their risk of developing type 2 diabetes by losing a significant amount of weight, according to new research. The study found that those who lost 10 percent or more of their body weight had an 85 percent lower risk of developing diabetes within three years, while those who lost 5 percent to 7 percent of their body weight had a 54 percent lower risk. The findings offer patients and doctors a guide to how short-term behavior change may affect long-term health, the researchers said. "We have known for some time that the greater the weight loss, the lower your risk of diabetes," study leader Dr. Nisa Maruthur, an assistant professor in the division of general internal medicine at the Johns Hopkins University School of Medicine, said in a Hopkins news release. "Now we understand that we can see much of the benefit of losing ... Read more

Related support groups: Obesity, Diabetes, Type 2, Pre-Diabetes

Diabetes-Linked Amputations Declining, Study Finds

Posted 19 Jul 2013 by Drugs.com

FRIDAY, July 19 – Many fewer foot and leg amputations are being performed on people with diabetes, even as rates of the disease are rising in the United States, a new study finds. Drastic diabetes-related amputations were cut by nearly half over the past decade, researchers report in the July issue of the journal Foot & Ankle International. Because of long-term nerve damage, people with diabetes face up to a 25 percent lifetime risk of amputation, according to prior research. For this study, researchers reviewed Medicare claims from 2000 to 2010 to see who had leg, feet and toe amputations and why. The results surprised them. "The trend was so clear and more obvious than I thought it would be," said senior author Dr. Phinit Phisitkul, an assistant clinical professor at the University of Iowa department of orthopedics and rehabilitation. The rate for upper and lower leg amputations fell ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1

Diabetes Drug May Protect the Brain

Posted 15 Jul 2013 by Drugs.com

MONDAY, July 15 – The diabetes drug metformin may do more than help control blood sugar levels: New research suggests it may also reduce the risk of dementia. Compared to people taking another class of diabetes medications called sulfonylureas, those taking metformin had a 20 percent reduced risk of developing dementia over the five-year study period. "Metformin could have a possible neuroprotective effect in the brain," said study author Dr. Rachel Whitmer, an epidemiologist in the division of research at Kaiser Permanente in Oakland, Calif. Whitmer, however, added a caveat: "This was an observational, retrospective, population-based study. We found an association, but didn't prove cause and effect." Whitmer is scheduled to present the findings Monday at the Alzheimer's Association International Conference in Boston. Research presented at medical meetings should be viewed as ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet

Early Diabetes Signs Often Missed in Alzheimer's Patients

Posted 14 Jul 2013 by Drugs.com

SUNDAY, July 14 – Undiagnosed prediabetes and diabetes are common in people with early Alzheimer's disease, a researcher says. Georgetown University neurologist Dr. R. Scott Turner made the finding when he began enrolling people with mild to moderate Alzheimer's disease into a study last year. The study's goal was to determine if resveratrol, a compound found in red grapes and red wine, might change blood sugar (glucose) levels in patients with mild to moderate Alzheimer's disease. Turner said he was shocked by what he found in this group of patients because they were already under a doctor's care, and those with known diabetes were excluded from the study. "The number of people with glucose intolerance (prediabetes) was much higher than expected," Turner said in a university medical center news release. "I was surprised by how many people didn't know they were prediabetic, and these ... Read more

Related support groups: Diabetes, Type 2, Alzheimer's Disease

Development of New Diabetes Drug Halted by Maker

Posted 10 Jul 2013 by Drugs.com

WEDNESDAY, July 10 – The development of what might have become a significant diabetes drug has been halted by its maker amid concerns that the medication raises the risk for fractures, kidney problems and heart failure in those taking it. Roche reported Wednesday that it would shut down a late-stage clinical trial of the drug aleglitazar after a monitoring committee found signs of troubling side effects and a lack of effectiveness in patients with type 2 diabetes who had heart problems. The Swiss pharmaceutical giant also closed all other studies of the drug. "We are disappointed by this outcome as we hoped that aleglitazar would provide significant benefit for patients with type 2 diabetes who are at risk of cardiovascular disease," Dr. Hal Barron, chief medical officer at Roche, said in a company statement. The drug was being tested to see if it could prevent heart attacks and ... Read more

Related support groups: Diabetes, Type 2

Quitting Smoking May Boost Diabetes Risk Slightly in Older Women

Posted 2 Jul 2013 by Drugs.com

TUESDAY, July 2 – Although quitting cigarettes helps the heart and lungs, a new study suggests that postmenopausal women who quit smoking need to guard against weight gain that can lead to diabetes. Still, "stopping smoking substantially decreases the risk of developing heart disease for postmenopausal women with and without diabetes," said lead investigator Juhua Luo, an assistant professor of epidemiology and biostatistics at the Indiana University School of Public Health in Bloomington. However, "because gaining more than 11 pounds may lessen the benefit, women should try to avoid gaining more than this amount," she said. "Our study shows that it is never too late to benefit from quitting smoking." The report was published in the July 3 issue of the Journal of the American Medical Association. In evaluating the study, Dr. Norman Edelman, chief medical officer for the American Lung ... Read more

Related support groups: Obesity, Diabetes, Type 2, Smoking Cessation

Pain Reliever Lowers Blood Sugar in Type 2 Diabetics, Study Says

Posted 1 Jul 2013 by Drugs.com

MONDAY, July 1 – An aspirin-like drug appears to lower blood sugar in people with type 2 diabetes, according to new research. A study of the drug – the prescription pain reliever salsalate – also found it reduced inflammation associated with type 2 diabetes. But it produced unwelcome side effects that could limit its potential as a diabetes treatment. "This trial is a test of possibly the oldest drug in Western use, and, because it's so old, there are no clinical trials on it," said study senior author Dr. Steven Shoelson, a professor of medicine at Harvard Medical School in Boston. "This trial was for a full year and showed that salsalate does lower blood glucose," said Shoelson, who is also the associate research director at the Joslin Diabetes Center in Boston. The study, published in the July 2 issue of the Annals of Internal Medicine, included 286 people between 18 and 75 years ... Read more

Related support groups: Diabetes, Type 2, Salsalate, Argesic-SA, Marthritic, Salflex, Anaflex, Disalcid, Mono-Gesic, Salsitab, Amigesic

Exercise Alone May Help Those With Type 2 Diabetes

Posted 25 Jun 2013 by Drugs.com

TUESDAY, June 25 – Exercise benefits people with type 2 diabetes even if they don't make any other lifestyle or diet changes, a new study says. Dutch researchers conducted MRI exams of 12 patients with diabetes before and after they did six months of moderate-intensity exercise. Each week, the participants, who were an average age of 46, exercised between three and a half and six hours a week during two endurance and two resistance training sessions. The six-month exercise program ended with a 12-day trekking expedition, according to the study published online in the journal Radiology. There were no changes in the participants' heart function at the end of the exercise program. But they did have significant decreases in the amount of fat in the abdomen, liver and around the heart, all of which have been shown to be associated with increased risk of heart disease. "In the present study, ... Read more

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Diet-Exercise Combo Doesn't Cut Heart Risks in Type 2 Diabetes Patients

Posted 24 Jun 2013 by Drugs.com

MONDAY, June 24 – Weight loss accomplished from diet and exercise does not appear to cut the risk of heart problems for people with diabetes, a new study finds. Lifestyle changes have long been the bedrock of treatment for type 2 diabetes. Doctors advise patients to eat carefully and stay active to help control blood sugar and cut the risk of long-term complications, which include at least a doubling in the risk for heart attacks and strokes. But the new study, published online June 24 in the New England Journal of Medicine, suggests that the benefits of diet and exercise may be more limited than previously believed. Even so, researchers say, people with diabetes shouldn't give up on their efforts to eat less and move more. Additional findings from the study being presented at an American Diabetes Association meeting in Chicago show that lifestyle changes may have benefits beyond the ... Read more

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Could Catching Up on Sleep Lower Your Diabetes Risk?

Posted 18 Jun 2013 by Drugs.com

TUESDAY, June 18 – Catching up on your sleep on weekends may help protect you from developing diabetes, a small, early study suggests. The study found significant improvements in insulin sensitivity – the body's ability to clear sugar from the blood – among sleep-deprived men after they had three nights of extra sleep. "We all know we need to get adequate sleep, but that is often impossible because of work demands and busy lifestyles," Dr. Peter Liu, a researcher at the Los Angeles Biomedical Research Institute, said in an institute news release. "Our study found extending the hours of sleep can improve the body's use of insulin, thereby reducing the risk of type 2 diabetes in adult men," Liu said. "Reducing the incidence of this chronic illness is critical for a nation where diabetes affects nearly 26 million people and costs an estimated $174 billion annually." The study included ... Read more

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Red Meat Linked to Increased Diabetes Risk

Posted 17 Jun 2013 by Drugs.com

MONDAY, June 17 – People who eat a lot of red meat increase their risk of developing type 2 diabetes, while those who cut down on red meat cut their risk. Those are the findings of a large new study out of Singapore involving 149,000 U.S. men and women. The researchers found that increasing the consumption of red meat can increase the risk of developing type 2 diabetes by 48 percent. "There is no need to have more red meat on your plate; it increases the risk of diabetes," said lead researcher An Pan, an assistant professor at the Saw Swee Hock School of Public Health at the National University of Singapore. "It is better to reduce your red meat consumption by replacing it with other healthy food choices, like beans, legumes, soy products, nuts, fish, poultry and whole grains," he added. The report was published in the June 17 online edition of the journal JAMA Internal Medicine. For ... Read more

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Skipping Breakfast May Raise Diabetes Risk

Posted 17 Jun 2013 by Drugs.com

SUNDAY, June 16 – Eating breakfast every day may help overweight women reduce their risk of diabetes, a small new study suggests. When women skipped the morning meal, they experienced insulin resistance, a condition in which a person requires more insulin to bring their blood sugar into a normal range, explained lead researcher Dr. Elizabeth Thomas, an instructor of medicine at the University of Colorado. This insulin resistance was short-term in the study, but when the condition is chronic, it is a risk factor for diabetes, Thomas said. She is due to present her findings this weekend at the Endocrine Society's annual meeting in San Francisco. "Eating a healthy breakfast is probably beneficial," Thomas said. "It may not only help you control your weight but avoid diabetes." Diabetes has been diagnosed in more than 18 million Americans, according to the American Diabetes Association. ... Read more

Related support groups: Diabetes, Type 2

Short Strolls After Meals May Lower Diabetes Risk

Posted 12 Jun 2013 by Drugs.com

WEDNESDAY, June 12 – Older adults at risk for getting diabetes who took a 15-minute walk after every meal improved their blood sugar levels, a new study shows. Three short walks after eating worked better to control blood sugar levels than one 45-minute walk in the morning or evening, said lead researcher Loretta DiPietro, chairwoman of the George Washington University School of Public Health and Health Services in Washington, D.C. "More importantly, the post-meal walking was significantly better than the other two exercise prescriptions at lowering the post-dinner glucose level," DiPietro added. The after-dinner period is an especially vulnerable time for older people at risk of diabetes, DiPietro said. Insulin production decreases, and they may go to bed with extremely high blood glucose levels, increasing their chances of diabetes. About 79 million Americans are at risk for type 2 ... Read more

Related support groups: Diabetes, Type 2

Low Blood Sugar May Raise Dementia Risk in Diabetics: Study

Posted 10 Jun 2013 by Drugs.com

MONDAY, June 10 – Low blood sugar in older adults with type 2 diabetes may increase their risk of dementia, a new study suggests. While it's important for diabetics to control blood sugar levels, that control "shouldn't be so aggressive that you get hypoglycemia," said study author Dr. Kristine Yaffe, a professor of psychiatry, neurology and epidemiology at the University of California, San Francisco. The study of nearly 800 people, published online June 10 in JAMA Internal Medicine, found that people with episodes of significant hypoglycemia – low blood sugar – had twice the chance of developing dementia, Yaffe said. Conversely, "if you had dementia you were also at a greater risk of getting hypoglycemic, compared with people with diabetes who didn't have dementia," she said. People with type 2 diabetes, by far the most common form of the disease, either don't make or don't properly ... Read more

Related support groups: Diabetes, Type 2, Dementia

Even Mild Weight Loss May Lower Diabetes Risk in Obese Teens

Posted 9 Jun 2013 by Drugs.com

FRIDAY, June 7 – Obese teens don't need to lose large amounts of weight to lower their risk of developing diabetes, according to a new study. Researchers found that obese teens who reduced their body-mass index (BMI) by 8 percent or more had improvements in insulin sensitivity, a measure of how well the body processes insulin and an important risk factor for developing type 2 diabetes. BMI is a measurement of body fat based on height and weight. "This threshold effect that occurs at 8 percent suggests that obese adolescents don't need to lose enormous amounts of weight to achieve improvements," study co-author Dr. Lorraine Levitt Katz, a pediatric endocrinologist at the Diabetes Center for Children at the Children's Hospital of Philadelphia, said in a hospital news release. "The improvements in insulin sensitivity occurred after four months of participating in a lifestyle-modification ... Read more

Related support groups: Obesity, Diabetes, Type 2

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Diabetic Ketoacidosis (in DM Type II), Diabetic Coma (in DM Type II), Diabetes Mellitus

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