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Related terms: Noninsulin-dependent Diabetes, Type 2 Diabetes, Diabetes, Type 2

FDA Approves Jardiance - New Type 2 Diabetes Drug

Posted 1 Aug 2014 by Drugs.com

FRIDAY, Aug. 1, 2014 – The U.S. Food and Drug Administration announced on Friday that it approved a new drug, Jardiance, to help fight type 2 diabetes. Jardiance (empagliflozin) "can be used alone or added to existing treatment regimens to control blood sugar levels in the overall management of diabetes," Dr. Curtis Rosebraugh, director of the Office of Drug Evaluation II in the FDA's Center for Drug Evaluation and Research, said in an agency statement. The FDA also recommended that Jardiance be used along with lifestyle changes, such as eating a healthy diet and exercising regularly. The combination of medication and lifestyle modification may improve blood sugar management for people with type 2 diabetes, they said. Over 26 million Americans are currently affected by type 2 diabetes, which accounts for about 90 percent of cases of diabetes, according to the agency. Jardiance, made by ... Read more

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FDA Approves Jardiance (empagliflozin) to Treat Type 2 Diabetes

Posted 1 Aug 2014 by Drugs.com

August 1, 2014 – The U.S. Food and Drug Administration today approved Jardiance (empagliflozin) tablets as an addition to diet and exercise to improve glycemic control in adults with type 2 diabetes. Type 2 diabetes affects approximately 26 million people and accounts for more than 90 percent of diabetes cases diagnosed in the United States. Over time, high blood sugar levels can increase the risk for serious complications, including heart disease, blindness, and nerve and kidney damage. "Jardiance provides an additional treatment option for the care of patients with type 2 diabetes," said Curtis J. Rosebraugh, M.D., M.P.H., director of the Office of Drug Evaluation II in the FDA’s Center for Drug Evaluation and Research. “It can be used alone or added to existing treatment regimens to control blood sugar levels in the overall management of diabetes.” Jardiance is a sodium glucose co ... Read more

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Big Jump in Doctor's Office Visits for Young Adults With Diabetes

Posted 31 Jul 2014 by Drugs.com

THURSDAY, July 31, 2014 – A new report finds that by 2010, one in every 10 visits Americans made to their doctor's office involved diabetes, with the greatest rise among those aged 25 to 44. Data from the U.S. Centers for Disease Control and Prevention found the number of office visits for patients with diabetes in this age group jumped by 34 percent between 2005 and 2010. Almost 29 million Americans have diabetes, the CDC said, and managing the blood sugar disease costs almost $245 billion each year. Diabetes falls into two categories: Type 1, which is typically inherited and comprises about 5 percent of cases, and type 2, which is closely tied to obesity and makes up 95 percent of cases. Overall, the new report from the CDC's National Center for Health Statistics (NCHS) found that office-based visits for diabetes patients rose by 20 percent – from 94.4 million in 2005 to 113.3 ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Chronic Medical Conditions Can Shorten Seniors' Lives: Study

Posted 28 Jul 2014 by Drugs.com

MONDAY, July 28, 2014 – The more chronic medical conditions people have at retirement age, the shorter their life expectancy may be, a new study claims. Since nearly four in five older Americans have multiple health issues, scientists at Johns Hopkins Bloomberg School of Public Health in Baltimore said the findings may help explain why gains in life expectancy are slowing in the United States. "Living with multiple chronic diseases such as diabetes, kidney disease and heart failure is now the norm and not the exception in the United States," said lead author Eva DuGoff in a Hopkins news release. "The medical advances that have allowed sick people to live longer may not be able to keep up with the growing burden of chronic disease." "It is becoming very clear that preventing the development of additional chronic conditions in the elderly could be the only way to continue to improve life ... Read more

Related support groups: Diabetes, Type 2, Heart Failure, Congestive Heart Failure, Chronic Kidney Disease

Study Links Shift Work to Risk for Type 2 Diabetes

Posted 25 Jul 2014 by Drugs.com

THURSDAY, July 24, 2014 – Shift workers, especially men, may be at higher risk for type 2 diabetes compared to people not on such schedules, a new study suggests. Also at special risk are shift workers who don't work on a set schedule, with shifts moving around at various times of the day. The findings are "not at all surprising," said one expert, Dr. Alan Manevitz, a clinical psychiatrist at Lenox Hill Hospital in New York City. "Physicians have long known that working shifts disrupts many key body chemicals, creating a ripple effect that can lead to ailments such as gastrointestinal disorders, cardiovascular disease and even cancer," he said. "Now type 2 diabetes can be added to this considerable list." In the new review, researchers analyzed data from 12 international studies involving more than 226,500 people. The study, led by Zuxun Lu of Huazhong University of Science and ... Read more

Related support groups: Diabetes, Type 2, Shift Work Sleep Disorder

High-Salt Diets Could Double Risk of Heart Woes for Diabetics

Posted 22 Jul 2014 by Drugs.com

TUESDAY, July 22, 2014 – A diet loaded with salt is associated with double the risk of heart attack or stroke in people with type 2 diabetes. The risk skyrockets even higher among those whose diabetes isn't well-managed, a new Japanese study reports. The study found that people with diabetes who consumed an average of 5.9 grams of sodium daily had double the risk of developing heart disease than those who consumed, on average, 2.8 grams of sodium daily. In addition, heart disease risk jumped nearly 10-fold for people with poorly managed type 2 diabetes and a diet with excess salt. However, it's important to note that this study only found an association between salt intake and increased heart disease; the study wasn't designed to prove that the increased salt intake actually caused heart disease. Still, experts believe it's important to limit salt in the diet. "The findings are very ... Read more

Related support groups: Diabetes, Type 2, Heart Attack, Myocardial Infarction

Protein Temporarily Reversed Type 2 Diabetes in Mice

Posted 16 Jul 2014 by Drugs.com

WEDNESDAY, July 16, 2014 – A single injection of a certain protein temporarily reversed symptoms of diabetes in mice, researchers report. The mice had diet-induced diabetes, which is the equivalent of type 2 diabetes in people. The injection of the protein FGF1 restored their blood sugar levels to a healthy range for more than two days. It also reversed insulin insensitivity, which is the underlying cause of diabetes. The injection did not cause the kinds of side effects commonly seen with many diabetes medications, according to the Salk Institute scientists, who report their findings in the July 16 issue of Nature. The findings could help in efforts to develop safer, more effective diabetes drugs for people, the researchers said. "Controlling glucose [blood sugar] is a dominant problem in our society," study co-corresponding author Ronald Evans, director of Salk's Gene Expression ... Read more

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Aerobic/Strength Training Combo May Be Best Workout for Diabetics

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – A combination of aerobic and resistance training may work better than either type of exercise alone in helping people with diabetes control their blood sugar, a new review finds. Researchers analyzed data from 14 studies that included more than 900 people with type 2 diabetes. The studies looked at the role of aerobic or resistance training (workouts such as weightlifting) in boosting the health of diabetics. Compared with either aerobic or resistance training alone, a regimen that combined both types of workouts was more effective in controlling blood sugar (glucose), blood fats, blood pressure and weight, the researchers said. The combination approach also helped more people reach higher levels of good cholesterol, according to the findings published July 2 in the journal Diabetologia. The Austrian researchers added that there is evidence that supervised ... Read more

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Insulin Pumps May Outperform Daily Injections for Type 2 Diabetes: Study

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – Insulin pumps provide better blood sugar control for adults with diabetes than multiple daily insulin injections, a new study says. Insulin pumps are small devices that are worn by patients and deliver constant amounts of insulin to the body through a catheter placed under the skin. The multicenter, international study was funded by medical device maker Medtronic and included 331 people aged 30 to 75. All of the patients had poorly controlled type 2 diabetes and were using multiple daily injections of insulin to control their blood sugar levels. The patients were randomly assigned to either continue using injections or to switch to an insulin pump. After six months, patients who used the insulin pumps had a much greater reduction in average blood sugar levels than those who used injections, the study found. According to the researchers, twice as many patients ... Read more

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FDA Approves Afrezza to Treat Diabetes

Posted 2 Jul 2014 by Drugs.com

June 27, 2014 – The U.S. Food and Drug Administration today approved Afrezza (insulin human) Inhalation Powder, a rapid-acting inhaled insulin to improve glycemic control in adults with diabetes mellitus. Afrezza is a rapid-acting inhaled insulin that is administered at the beginning of each meal. An estimated 25.8 million (18.8 million diagnosed and 7.0 million undiagnosed) people in the United States or approximately 8.3 percent of the population–have diabetes. Over time, high blood sugar levels can increase the risk for serious complications, including heart disease, blindness and nerve and kidney damage. "Afrezza is a new treatment option for patients with diabetes requiring mealtime insulin," said Jean-Marc Guettier, M.D., director of the Division of Metabolism and Endocrinology Products in the FDA’s Center for Drug Evaluation and Research. “Today’s approval broadens the options ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Inhaled Medication Afrezza Approved to Treat Diabetes

Posted 30 Jun 2014 by Drugs.com

MONDAY, June 30, 2014 – An inhaled medication, Afrezza (human insulin), has been approved by the U.S. Food and Drug Administration to treat adults with diabetes. The rapid-acting, inhaled insulin is designed to be used within 20 minutes of beginning a meal, the agency said. Diabetes affects an estimated 25.8 million people in the United States, including 7 million who haven't been diagnosed, the FDA said in a news release. Serious complications could include heart disease, blindness and damage to the nerves and kidneys. Afrezza's safety and effectiveness were evaluated in clinical studies involving more than 3,000 people, of whom about two-thirds had type 2 diabetes and the rest had type 1 diabetes. The drug is not meant to replace long-acting insulin, and must be used in combination with long-acting insulin in people with type 1 disease, the FDA said. It should not be used to treat ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

FDA Approves Afrezza Inhaled Diabetes Medication

Posted 29 Jun 2014 by Drugs.com

SATURDAY, June 28, 2014 – People with type 1 or 2 diabetes now have a new means of getting their medication, with the U.S. Food and Drug Administration's approval on Friday of the first inhaled medicine for the blood sugar disease. The drug, Afrezza, "is a new treatment option for patients with diabetes requiring mealtime insulin," Dr. Jean-Marc Guettier, director of the Division of Metabolism and Endocrinology Products in the FDA's Center for Drug Evaluation and Research, said in an agency news release on Friday. He said that Afrezza's approval "broadens the options available for delivering mealtime insulin in the overall management of patients with diabetes who require it to control blood sugar levels." Diabetes falls into two main categories: type 1, an autoimmune illness which is often inherited and involves a dysfunction of insulin-producing cells in the pancreas; and type 2, ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

FDA Medwatch Alert: Olmesartan: Drug Safety Communication - FDA Review Finds Cardiovascular Risks for Diabetics Not Conclusive

Posted 24 Jun 2014 by Drugs.com

Includes: Benicar, Benicar HCT, Azor, Tribenzor, and Generics [Posted 06/24/2014] ISSUE: FDA has completed its safety review and has found no clear evidence of increased cardiovascular risks associated with use of the blood pressure medication olmesartan in diabetic patients (see previous alerts linked below). FDA believes the benefits of olmesartan in patients with high blood pressure continue to outweigh the potential risks. BACKGROUND: FDA safety review was prompted by the results of the ROADMAP trial. The ROADMAP (Randomized Olmesartan and Diabetes Microalbuminuria Prevention) clinical trial examined the effects of olmesartan in patients with type 2 diabetes, to see whether olmesartan could delay kidney damage. There was an unexpected finding of increased risk of cardiovascular death in the olmesartan group compared to the group taking a placebo, or sugar pill. However, the risk ... Read more

Related support groups: Diabetes, Type 2, Benicar, Azor, Benicar HCT, Olmesartan, Tribenzor, Amlodipine/hydrochlorothiazide/olmesartan, Amlodipine/Olmesartan, Hydrochlorothiazide/Olmesartan

Gut Microbes Differ in Obese or Diabetic People, Study Finds

Posted 23 Jun 2014 by Drugs.com

MONDAY, June 23, 2014 – Obese people and those with type 2 diabetes have lower levels of common types of "good" intestinal bacteria than healthy people, a new study reveals. The findings may be important, because measuring populations of these bacteria and other microscopic organisms in the intestines could help spot people at risk for obesity and diabetes, or the bacteria might offer targets for treating these conditions, the researchers said. The study was presented Sunday at the annual joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago. "Further studies should be carried out to elucidate if the gut microbial changes are a cause or effect of metabolic diseases," study lead investigator Dr. Yalcin Basaran, an endocrinologist from Gulhane Military Medical Academy School of Medicine in Ankara, Turkey, said in a meeting news release. ... Read more

Related support groups: Obesity, Diabetes, Type 2

People With Heart Disease, Diabetes May Be More Likely to Stay on Statins

Posted 23 Jun 2014 by Drugs.com

MONDAY, June 23, 2014 – People who have heart disease or diabetes, the overweight or obese and former smokers are most likely to keep taking cholesterol-lowering statins, a new study finds. Previous research has shown that as many 46 percent of patients who are prescribed statins stop taking them. Nearly one in 10 cardiovascular events are linked to failure to take prescribed drugs, according to background information in the study. Researchers looked at a group of people from Finland who began taking statins between 1998 and 2010. The people most likely to stop taking statins were women, single people and those aged 24 to 50. People without heart disease or diabetes were less likely to continue taking statins than those with the conditions. Among patients without heart disease or diabetes, those who were most likely to continue taking statins were overweight/obese or former smokers. ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Altoprev, Fluvastatin, Baycol

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