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Diabetes, Type 2 Blog

Related terms: Noninsulin-dependent Diabetes, Type 2 Diabetes, Diabetes, Type 2

Insulin-Metformin Combo Tied to Poorer Survival in Diabetes Study

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – The combination of metformin and insulin for people with type 2 diabetes may slightly increase death rates among patients, according to researchers from Vanderbilt University. However, other experts question the study's conclusions and claim it is at odds with other better-designed studies that show the combination of metformin and insulin is both safe and effective. "Insulin remains a reasonable option for patients who have very high glucose [blood sugar] or who desire flexible and fast blood sugar control, but most patients taking metformin prefer to delay starting insulin," said lead researcher Dr. Christianne Roumie, an associate professor of internal medicine and pediatrics at Vanderbilt University in Nashville, Tenn. "The current study suggests that adding a sulfonylurea to metformin should be preferred to adding insulin for most patients who need a ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet

U.S. Diabetes Rate Jumps to 29 Million: CDC

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – The number of Americans with diabetes rose from 26 million in 2010 to 29 million – 9 percent of the population – in 2012, a new federal government study finds. One in every four people with diabetes does not even realize it, according to the report from the U.S. Centers for Disease Control and Prevention. Another 86 million American adults – more than one-third of adults – have what doctors call "prediabetes. " This means their blood sugar levels are higher than normal but not yet high enough to be classified as type 2 diabetes, the CDC said. Rates of prediabetes are similar for blacks (39 percent), Hispanics (38 percent) and whites (35 percent). "These new numbers are alarming, and underscore the need for an increased focus on reducing the burden of diabetes in our country," Ann Albright, director of CDC's Division of Diabetes Translation, said in an ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Pre-Diabetes, Diabetes Mellitus

Sleep Apnea May Raise Risk of Diabetes, Research Suggests

Posted 10 Jun 2014 by Drugs.com

FRIDAY, June 6, 2014 – A study of more than 8,600 people suffering from sleep apnea suggests a possible increased risk for developing diabetes, Canadian researchers report. They noted that sleep apnea results in less oxygen reaching cells in the body, less sleep and an increased heart rate, all of which are associated with a biological link to diabetes. "Controlling for known risk factors for diabetes – including age, sex, weight, smoking, other medical problems and income status – patients with severe sleep apnea had a 30 percent higher risk of developing diabetes than those without sleep apnea," said lead researcher Dr. Tetyana Kendzerska. She's with the University of Toronto's Institute of Health Policy, Management and Evaluation. Obesity, an important risk factor or both diabetes and sleep apnea, was taken into account. "We controlled for body-mass index [a measure of weight and ... Read more

Related support groups: Diabetes, Type 2, Sleep Apnea

For Obese Diabetics, Weight-Loss Surgery May Work Best

Posted 4 Jun 2014 by Drugs.com

WEDNESDAY, June 4, 2014 – Compared to diet and lifestyle changes, gastric bypass surgery appears to be the clear winner in helping obese people with type 2 diabetes lose weight and even rid themselves of the disease, new studies show. The findings "further confirm that gastric bypass is the most effective way of treating type 2 diabetes in obese patients, and that surgery is superior to medical treatment for the disease in terms of blood sugar control," said Dr. Subhash Kini, a bariatric surgeon and associate professor of surgery at the Icahn School of Medicine and The Mount Sinai Hospital, in New York City. He was not involved in the two new studies. The findings were published June 4 in JAMA Surgery. As obesity rates in the United States continue to rise, so do rates of obesity-linked type 2 diabetes. For years, improved diet, lifestyle changes and certain weight-loss medications ... Read more

Related support groups: Obesity, Diabetes, Type 2

1 in 10 Heart Attack Patients May Have Undiagnosed Diabetes

Posted 3 Jun 2014 by Drugs.com

TUESDAY, June 3, 2014 – As many as one in 10 Americans who has a heart attack may also have undiagnosed diabetes, a new study finds. "Diagnosing diabetes in patients who have had a heart attack is important because of the role diabetes plays in heart disease," lead author Dr. Suzanne Arnold, assistant professor at Saint Luke's Mid America Heart Institute and the University of Missouri at Kansas City, said in an American Heart Association (AHA) news release. "By recognizing and treating diabetes early, we may be able to prevent additional cardiovascular complications through diet, weight loss and lifestyle changes, in addition to taking medications. Another important reason to diagnose diabetes at the time of heart attack is that it can guide the treatments for the patient's coronary artery disease," she explained. For the study, researchers analyzed data from more than 2,800 heart ... Read more

Related support groups: Diabetes, Type 2, Heart Attack, Myocardial Infarction

Diabetics Fare Worse After Heart Surgery, Study Finds

Posted 29 May 2014 by Drugs.com

THURSDAY, May 29, 2014 – People with diabetes have an increased risk of problems after heart bypass surgery, a new study finds. Researchers looked at more than 9,200 patients in China who underwent coronary artery bypass graft surgery (CABG) between 1999 and 2008, and found that those with diabetes had worse outcomes after two years than those without the condition. Costs were also higher among patients with diabetes, according to the study in the June issue of the Annals of Thoracic Surgery. These expenses were mainly due to additional hospitalizations and medical procedures, and the use of insulin and other medications. "Based on the results of our study, we highly recommend an individualized treatment plan and a heart team approach for patients with diabetes who require CABG surgery," lead author Dr. Heng Zhang, of Fuwai Hospital in China, said in a journal news release. "We also ... Read more

Related support groups: Surgery, Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Diabetes May Be Bigger Threat to the Female Heart: Study

Posted 25 May 2014 by Drugs.com

THURSDAY, May 22, 2014 – Diabetes appears to pose a greater risk to heart health for women than men, a new analysis of current research contends. "The risk of coronary heart disease conferred by diabetes is between 40 percent to 50 percent greater for women than for men," said study co-author Rachel Huxley, director of the Queensland Clinical Trials and Biostatistics Centre at the University of Queensland in Australia. The results support findings from an earlier analysis that found that women with diabetes have a nearly 50 percent increased risk of death from heart disease compared to men with diabetes, the study authors said. This difference could stem from the fact that men develop full-blown type 2 diabetes earlier than women and at a lower weight, Huxley said. Because of this, men receive aggressive treatment sooner both for their diabetes and potential heart health risks, such as ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Kids' Diabetes Rates Up Dramatically in 8 Years, Study Finds

Posted 6 May 2014 by Drugs.com

SATURDAY, May 3, 2014 – Rates of diabetes in U.S. children have jumped sharply in just eight years, according to new research. The prevalence of type 1 diabetes increased 21 percent between 2001 and 2009. At the same time, rates of type 2 diabetes rose 30.5 percent, the study found. These increases affected both boys and girls, and nearly all racial groups, the researchers noted. The reasons behind the increases aren't entirely clear, said lead researcher Dr. Dana Dabelea, the associate dean for faculty at the Colorado School of Public Health in Aurora. "While we do not completely understand the reasons for this increase, since the causes of type 1 diabetes are still unclear, it is likely that something has changed in our environment, both in the U.S. and elsewhere in the world, causing more youth to develop the disease, maybe at increasingly younger ages," she said. Several reasons ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1

Health Tip: Risk Factors for Type 2 Diabetes

Posted 1 May 2014 by Drugs.com

-- While you can't control all risk factors for type 2 diabetes, you can take steps to help ward off the disease. The National Diabetes Information Clearinghouse mentions these common risk factors for type 2 diabetes: Being overweight or obese. Having blood pressure of 140/90 or higher, or high cholesterol. Leading a sedentary lifestyle. Having cardiovascular disease. Being age 45 or older. Having an immediate family member with diabetes. Being of Alaskan Native, African-American, Asian American, American Indian, Pacific Island or Hispanic/Latino origin. Having had a baby weighing more than 9 pounds, or having had gestational diabetes. Read more

Related support groups: Diabetes, Type 2

Type 2 Diabetes May Shrink the Brain, Study Suggests

Posted 29 Apr 2014 by Drugs.com

TUESDAY, April 29, 2014 – People with type 2 diabetes may lose more brain volume than is expected as they age, new research indicates. Surprisingly, this shrinkage doesn't appear to be linked to the damaging effect of diabetes on tiny blood vessels in the brain, but instead by how the brain handles excess sugar, the researchers noted. "We have known for a long time that diabetes is not good for the brain," said lead researcher Dr. R. Nick Bryan, a professor of radiology at the University of Pennsylvania's Perleman School of Medicine in Philadelphia. Diabetes is associated with an increased risk for stroke and dementia, he said. Until now, doctors have thought these risks were likely related to blood vessel damage related to diabetes. "But our study suggests that there is additional damage to the brain which may be more like a brain disorder such as Alzheimer's disease," Bryan said. "So ... Read more

Related support groups: Diabetes, Type 2

Low Blood Sugar May Affect Heartbeat in People With Diabetes

Posted 22 Apr 2014 by Drugs.com

TUESDAY, April 22, 2014 – Low blood sugar levels – known as hypoglycemia – in people with diabetes may cause potentially dangerous changes in heart rate, according to a small new study. This study's findings may help explain why a large-scale study found that very tight control of blood sugar levels in people with type 2 diabetes led to higher-than-expected death rates. It may also help explain why some otherwise healthy people with type 1 diabetes die during their sleep – sometimes called "dead-in-bed syndrome" – without an apparent cause, researchers say. "We found that hypoglycemia was fairly common and that nocturnal episodes in particular were generally marked by a pattern whereby glucose levels dropped to low levels for some hours during which patients slept," said Dr. Simon Heller, senior study author and a professor of clinical diabetes and honorary consultant physician at ... Read more

Related support groups: Diabetes, Type 2, Hypoglycemia, Bradyarrhythmia

FDA Approves Tanzeum (albiglutide) to Treat Type 2 Diabetes

Posted 16 Apr 2014 by Drugs.com

April 15, 2014 – The U.S. Food and Drug Administration today approved Tanzeum (albiglutide) subcutaneous injection to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes. Type 2 diabetes affects approximately 24 million people and accounts for more than 90 percent of diabetes cases diagnosed in the United States. Over time, high blood sugar levels can increase the risk for serious complications, including heart disease, blindness, and nerve and kidney damage. "Tanzeum is a new treatment option for the millions of Americans living with type 2 diabetes," said Curtis Rosebraugh, M.D., M.P.H., director of the Office of Drug Evaluation II in the FDA’s Center for Drug Evaluation and Research. “It can be used alone or added to existing treatment regimens to control blood sugar levels in the overall management of diabetes.” Tanzeum is a glucagon-like pepti ... Read more

Related support groups: Diabetes, Type 2

Obesity-Related Enzyme Targeted in Mouse Study

Posted 9 Apr 2014 by Drugs.com

WEDNESDAY, April 9, 2014 – An enzyme in the fat and liver of mice could take a key role in future attempts to battle obesity and type 2 diabetes, according to a new study. The enzyme – nicotinamide N-methyltransferase, or NNMT – appears to help regulate the ability of cells to burn energy efficiently, researchers report. By hampering the gene that produces the enzyme, researchers were able to keep mice fed a high-fat diet from gaining weight. The mice also became better at using insulin to process blood sugar, which could lower their odds for developing diabetes. "The mice were eating normally. It wasn't a food intake effect. They actually had increased energy expenditure," said senior author Dr. Barbara Kahn, vice chair of medicine at Beth Israel Deaconess Medical Center and a professor at Harvard Medical School. "For every calorie they ate, they burned up more energy." Controlling ... Read more

Related support groups: Obesity, Diabetes, Type 2

Diabetes Tied to Higher Risk of Pancreatic Cancer in Study

Posted 4 Apr 2014 by Drugs.com

FRIDAY, April 4, 2014 – People with diabetes have double the risk of pancreatic cancer compared to people who don't have diabetes, according to a new analysis of 88 previous studies. Diabetes has been considered a risk factor for pancreatic cancer, but what's not clear is which condition comes first. This new analysis suggests that at least for some people, pancreatic cancer might be responsible for diabetes. Experts note, however, that the overall risk for pancreatic cancer remains low among people with diabetes. "Our study demonstrated that there is an overall two-fold increased risk of pancreatic cancer in patients with diabetes mellitus," said Dr. Mehrdad Nikfarjam, a senior lecturer and transplant surgeon at the University of Melbourne, in Australia. Diabetes mellitus includes type 1 and type 2 diabetes. "The study also demonstrates that diabetes mellitus itself may be an early ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Pancreatic Cancer

Diabetes Treatment Falls Short as Heart Failure Drug in Study

Posted 31 Mar 2014 by Drugs.com

MONDAY, March 31, 2014 – A drug commonly used to treat diabetes does not help prevent heart failure in non-diabetics who've had a heart attack, according to a new study. Researchers said results from the rigorous clinical trial dispute previous findings that showed the drug, metformin, could have a protective effect on the heart. "While this glucose-lowering drug is very effective in patients with diabetes and can be safely used in patients with a heart attack, [our data show] it is not of additional benefit in protecting the heart from damage resulting in decreased pump function of the heart," said the study's lead investigator, Dr. Chris Lexis, of University Medical Center Groningen in the Netherlands. Heart attacks often damage heart muscle, which leads to reduced functioning of the left ventricle. This affects the ability of the heart to pump blood. Several animal studies have ... Read more

Related support groups: Diabetes, Type 2, Metformin, Heart Attack, Heart Failure, Congestive Heart Failure, Glucophage, Myocardial Infarction, Glucophage XR, Glumetza, Fortamet, Riomet

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