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Related terms: Noninsulin-dependent Diabetes, Type 2 Diabetes, Diabetes, Type 2

40 Percent of Americans Will Develop Diabetes, CDC Projects

Posted 12 Aug 2014 by Drugs.com

TUESDAY, Aug. 12, 2014 – Approximately two out of every five Americans will develop type 2 diabetes at some point during their adult lives, according to new U.S. government estimates. The ongoing diabetes and obesity epidemics have combined with ever-increasing human lifespans to increase lifetime risk of type 2 diabetes to about 40 percent for both men and women, said lead study author Edward Gregg, chief of the epidemiology and statistics branch in the division of diabetes translation at the U.S. Centers for Disease Control and Prevention (CDC). "We weren't necessarily surprised that it increased, but we didn't expect it to increase this much," Gregg said. "Forty percent is a humbling number." The odds are even worse for certain minority groups. Half of black women and Hispanic men and women are predicted to develop type 2 diabetes during their lifetime, the researchers reported. ... Read more

Related support groups: Obesity, Diabetes, Type 2

FDA Approves Invokamet (canagliflozin/metformin) for Type 2 Diabetes

Posted 11 Aug 2014 by Drugs.com

RARITAN, N.J., August 8, 2014 – Janssen Pharmaceuticals, Inc. announced today the U.S. Food and Drug Administration (FDA) has approved Invokamet, a fixed dose therapy combining canagliflozin and metformin hydrochloride in a single tablet, for the treatment of adults with type 2 diabetes. Invokamet provides the clinical attributes of Invokana (canagliflozin), the first sodium glucose co-transporter 2 (SGLT2) inhibitor available in the United States, together with metformin, which is commonly prescribed early in the treatment of type 2 diabetes. Invokamet is the first fixed-dose combination of an SGLT2 inhibitor with metformin approved in the United States. "Invokamet combines, in one tablet, two complementary therapeutic approaches proven effective for managing type 2 diabetes,” said Richard Aguilar, M.D.*, Medical Director of Diabetes Nation. "Canagliflozin works with the kidney to pro ... Read more

Related support groups: Diabetes, Type 2, Metformin, Invokana, Canagliflozin

Coaching May Help Diabetics Battle Depression, Disease Better

Posted 6 Aug 2014 by Drugs.com

WEDNESDAY, Aug. 6, 2014 – Mental health coaching may help diabetes patients with depression and with lowering their blood sugar levels, a new study suggests. Many people with diabetes suffer depression, which can interfere with their ability to manage their diabetes through monitoring blood sugar levels, being active, eating healthy and taking their medications, the researchers noted. This study included diabetes patients in a rural, low-income area of central North Carolina. Nearly 16 percent of people in this area have diabetes, compared with 10 percent of people nationally. Thirty percent of these diabetes patients have depression and 65 percent are poor, the study authors wrote. Researchers referred 182 patients with newly diagnosed type 2 diabetes and depression to a diabetes educator and also to a mental health coach, who helped them find ways to deal with the stresses and ... Read more

Related support groups: Depression, Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

The 'Bear' Facts on Obesity and Diabetes

Posted 6 Aug 2014 by Drugs.com

TUESDAY, Aug. 5, 2014 – The ways grizzly bears deal with hibernation and fluctuating weight might offer valuable new clues to human obesity and diabetes, new research suggests. The study authors note that the tissues of obese people with type 2 diabetes become dangerously insensitive to insulin, the hormone that helps control the level of sugar in the blood. However, unlike people, insulin levels in grizzly bears do not change, the researchers found. Instead, the bears' cells seem to be able to control their ability to respond to insulin. In fact, in the fall – when grizzly bears are most obese – they are also the most sensitive to insulin, says a team led by Dr. Kevin Corbit, of the drug maker Amgen, Inc. According to Corbit's group, this happens because the activity of a key protein found in fat cells, called PTEN, is shut down. In fact, weeks into hibernation, grizzly bears ... Read more

Related support groups: Obesity, Diabetes, Type 2

Poor People With Diabetes Much More Likely to Lose a Limb: Study

Posted 4 Aug 2014 by Drugs.com

MONDAY, Aug. 4, 2014 – Poor people with diabetes are much more likely to lose a limb to the disease than affluent patients are, new research suggests. Researchers from the University of California, Los Angeles, found the odds of having a toe, foot or leg amputated was up to 10 times higher for diabetics who live in low-income neighborhoods. Most of these amputations are preventable if patients are diagnosed and get proper medical care sooner, the study authors noted. They added that their findings should prompt public officials to implement laws that help reduce barriers to health care. "When you have diabetes, where you live directly relates to whether you'll lose a limb to the disease. Millions of Californians have undergone preventable amputations due to poorly managed diabetes," lead author Dr. Carl Stevens, a clinical professor of medicine at the David Geffen School of Medicine at ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Jardiance Approved for Type 2 Diabetes

Posted 4 Aug 2014 by Drugs.com

FRIDAY, Aug. 1, 2014 – Jardiance (empagliflozin) has been approved by the U.S. Food and Drug Administration to treat type 2 diabetes, which accounts for some 90 percent of diabetes cases in the United States, the agency said Friday in a news release. Affecting some 26 million people in the United States, the disease can lead to complications including heart disease, blindness and nerve and kidney damage, the FDA said. Jardiance, from a class of drugs called "sodium glucose co-transporter 2 inhibitors," is designed to block re-absorption of blood sugar by the kidneys. Its safety and effectiveness were evaluated in clinical studies involving 4,480 people with type 2 diabetes. The drug should not be used to treat type 1 diabetes, in people with severe kidney impairment, among people with increased ketones in the blood or urine, or in people on dialysis, the FDA said. The agency said it ... Read more

Related support groups: Diabetes, Type 2

FDA Approves Jardiance - New Type 2 Diabetes Drug

Posted 1 Aug 2014 by Drugs.com

FRIDAY, Aug. 1, 2014 – The U.S. Food and Drug Administration announced on Friday that it approved a new drug, Jardiance, to help fight type 2 diabetes. Jardiance (empagliflozin) "can be used alone or added to existing treatment regimens to control blood sugar levels in the overall management of diabetes," Dr. Curtis Rosebraugh, director of the Office of Drug Evaluation II in the FDA's Center for Drug Evaluation and Research, said in an agency statement. The FDA also recommended that Jardiance be used along with lifestyle changes, such as eating a healthy diet and exercising regularly. The combination of medication and lifestyle modification may improve blood sugar management for people with type 2 diabetes, they said. Over 26 million Americans are currently affected by type 2 diabetes, which accounts for about 90 percent of cases of diabetes, according to the agency. Jardiance, made by ... Read more

Related support groups: Diabetes, Type 2

FDA Approves Jardiance (empagliflozin) to Treat Type 2 Diabetes

Posted 1 Aug 2014 by Drugs.com

August 1, 2014 – The U.S. Food and Drug Administration today approved Jardiance (empagliflozin) tablets as an addition to diet and exercise to improve glycemic control in adults with type 2 diabetes. Type 2 diabetes affects approximately 26 million people and accounts for more than 90 percent of diabetes cases diagnosed in the United States. Over time, high blood sugar levels can increase the risk for serious complications, including heart disease, blindness, and nerve and kidney damage. "Jardiance provides an additional treatment option for the care of patients with type 2 diabetes," said Curtis J. Rosebraugh, M.D., M.P.H., director of the Office of Drug Evaluation II in the FDA’s Center for Drug Evaluation and Research. “It can be used alone or added to existing treatment regimens to control blood sugar levels in the overall management of diabetes.” Jardiance is a sodium glucose co ... Read more

Related support groups: Diabetes, Type 2

Big Jump in Doctor's Office Visits for Young Adults With Diabetes

Posted 31 Jul 2014 by Drugs.com

THURSDAY, July 31, 2014 – A new report finds that by 2010, one in every 10 visits Americans made to their doctor's office involved diabetes, with the greatest rise among those aged 25 to 44. Data from the U.S. Centers for Disease Control and Prevention found the number of office visits for patients with diabetes in this age group jumped by 34 percent between 2005 and 2010. Almost 29 million Americans have diabetes, the CDC said, and managing the blood sugar disease costs almost $245 billion each year. Diabetes falls into two categories: Type 1, which is typically inherited and comprises about 5 percent of cases, and type 2, which is closely tied to obesity and makes up 95 percent of cases. Overall, the new report from the CDC's National Center for Health Statistics (NCHS) found that office-based visits for diabetes patients rose by 20 percent – from 94.4 million in 2005 to 113.3 ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Chronic Medical Conditions Can Shorten Seniors' Lives: Study

Posted 28 Jul 2014 by Drugs.com

MONDAY, July 28, 2014 – The more chronic medical conditions people have at retirement age, the shorter their life expectancy may be, a new study claims. Since nearly four in five older Americans have multiple health issues, scientists at Johns Hopkins Bloomberg School of Public Health in Baltimore said the findings may help explain why gains in life expectancy are slowing in the United States. "Living with multiple chronic diseases such as diabetes, kidney disease and heart failure is now the norm and not the exception in the United States," said lead author Eva DuGoff in a Hopkins news release. "The medical advances that have allowed sick people to live longer may not be able to keep up with the growing burden of chronic disease." "It is becoming very clear that preventing the development of additional chronic conditions in the elderly could be the only way to continue to improve life ... Read more

Related support groups: Diabetes, Type 2, Heart Failure, Congestive Heart Failure, Chronic Kidney Disease

Study Links Shift Work to Risk for Type 2 Diabetes

Posted 25 Jul 2014 by Drugs.com

THURSDAY, July 24, 2014 – Shift workers, especially men, may be at higher risk for type 2 diabetes compared to people not on such schedules, a new study suggests. Also at special risk are shift workers who don't work on a set schedule, with shifts moving around at various times of the day. The findings are "not at all surprising," said one expert, Dr. Alan Manevitz, a clinical psychiatrist at Lenox Hill Hospital in New York City. "Physicians have long known that working shifts disrupts many key body chemicals, creating a ripple effect that can lead to ailments such as gastrointestinal disorders, cardiovascular disease and even cancer," he said. "Now type 2 diabetes can be added to this considerable list." In the new review, researchers analyzed data from 12 international studies involving more than 226,500 people. The study, led by Zuxun Lu of Huazhong University of Science and ... Read more

Related support groups: Diabetes, Type 2, Shift Work Sleep Disorder

High-Salt Diets Could Double Risk of Heart Woes for Diabetics

Posted 22 Jul 2014 by Drugs.com

TUESDAY, July 22, 2014 – A diet loaded with salt is associated with double the risk of heart attack or stroke in people with type 2 diabetes. The risk skyrockets even higher among those whose diabetes isn't well-managed, a new Japanese study reports. The study found that people with diabetes who consumed an average of 5.9 grams of sodium daily had double the risk of developing heart disease than those who consumed, on average, 2.8 grams of sodium daily. In addition, heart disease risk jumped nearly 10-fold for people with poorly managed type 2 diabetes and a diet with excess salt. However, it's important to note that this study only found an association between salt intake and increased heart disease; the study wasn't designed to prove that the increased salt intake actually caused heart disease. Still, experts believe it's important to limit salt in the diet. "The findings are very ... Read more

Related support groups: Diabetes, Type 2, Heart Attack, Myocardial Infarction

Protein Temporarily Reversed Type 2 Diabetes in Mice

Posted 16 Jul 2014 by Drugs.com

WEDNESDAY, July 16, 2014 – A single injection of a certain protein temporarily reversed symptoms of diabetes in mice, researchers report. The mice had diet-induced diabetes, which is the equivalent of type 2 diabetes in people. The injection of the protein FGF1 restored their blood sugar levels to a healthy range for more than two days. It also reversed insulin insensitivity, which is the underlying cause of diabetes. The injection did not cause the kinds of side effects commonly seen with many diabetes medications, according to the Salk Institute scientists, who report their findings in the July 16 issue of Nature. The findings could help in efforts to develop safer, more effective diabetes drugs for people, the researchers said. "Controlling glucose [blood sugar] is a dominant problem in our society," study co-corresponding author Ronald Evans, director of Salk's Gene Expression ... Read more

Related support groups: Diabetes, Type 2

Aerobic/Strength Training Combo May Be Best Workout for Diabetics

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – A combination of aerobic and resistance training may work better than either type of exercise alone in helping people with diabetes control their blood sugar, a new review finds. Researchers analyzed data from 14 studies that included more than 900 people with type 2 diabetes. The studies looked at the role of aerobic or resistance training (workouts such as weightlifting) in boosting the health of diabetics. Compared with either aerobic or resistance training alone, a regimen that combined both types of workouts was more effective in controlling blood sugar (glucose), blood fats, blood pressure and weight, the researchers said. The combination approach also helped more people reach higher levels of good cholesterol, according to the findings published July 2 in the journal Diabetologia. The Austrian researchers added that there is evidence that supervised ... Read more

Related support groups: Diabetes, Type 2

Insulin Pumps May Outperform Daily Injections for Type 2 Diabetes: Study

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – Insulin pumps provide better blood sugar control for adults with diabetes than multiple daily insulin injections, a new study says. Insulin pumps are small devices that are worn by patients and deliver constant amounts of insulin to the body through a catheter placed under the skin. The multicenter, international study was funded by medical device maker Medtronic and included 331 people aged 30 to 75. All of the patients had poorly controlled type 2 diabetes and were using multiple daily injections of insulin to control their blood sugar levels. The patients were randomly assigned to either continue using injections or to switch to an insulin pump. After six months, patients who used the insulin pumps had a much greater reduction in average blood sugar levels than those who used injections, the study found. According to the researchers, twice as many patients ... Read more

Related support groups: Diabetes, Type 2, Insulin, Lantus, Humalog, Novolog, Lantus Solostar, Levemir, Novolin R, Novolin N, Lantus Solostar Pen, Humulin N, Humulin R, NovoLog FlexPen, Humalog Pen, Humalog KwikPen, Insulin Glargine, Apidra, Novolin 70/30, Insulin Regular, NovoLog Mix 70/30

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