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Related terms: Noninsulin-dependent Diabetes, Type 2 Diabetes, Diabetes, Type 2

High-Salt Diets Could Double Risk of Heart Woes for Diabetics

Posted 1 day 5 hours ago by Drugs.com

TUESDAY, July 22, 2014 – A diet loaded with salt is associated with double the risk of heart attack or stroke in people with type 2 diabetes. The risk skyrockets even higher among those whose diabetes isn't well-managed, a new Japanese study reports. The study found that people with diabetes who consumed an average of 5.9 grams of sodium daily had double the risk of developing heart disease than those who consumed, on average, 2.8 grams of sodium daily. In addition, heart disease risk jumped nearly 10-fold for people with poorly managed type 2 diabetes and a diet with excess salt. However, it's important to note that this study only found an association between salt intake and increased heart disease; the study wasn't designed to prove that the increased salt intake actually caused heart disease. Still, experts believe it's important to limit salt in the diet. "The findings are very ... Read more

Related support groups: Diabetes, Type 2, Heart Attack, Myocardial Infarction

Protein Temporarily Reversed Type 2 Diabetes in Mice

Posted 7 days ago by Drugs.com

WEDNESDAY, July 16, 2014 – A single injection of a certain protein temporarily reversed symptoms of diabetes in mice, researchers report. The mice had diet-induced diabetes, which is the equivalent of type 2 diabetes in people. The injection of the protein FGF1 restored their blood sugar levels to a healthy range for more than two days. It also reversed insulin insensitivity, which is the underlying cause of diabetes. The injection did not cause the kinds of side effects commonly seen with many diabetes medications, according to the Salk Institute scientists, who report their findings in the July 16 issue of Nature. The findings could help in efforts to develop safer, more effective diabetes drugs for people, the researchers said. "Controlling glucose [blood sugar] is a dominant problem in our society," study co-corresponding author Ronald Evans, director of Salk's Gene Expression ... Read more

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Aerobic/Strength Training Combo May Be Best Workout for Diabetics

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – A combination of aerobic and resistance training may work better than either type of exercise alone in helping people with diabetes control their blood sugar, a new review finds. Researchers analyzed data from 14 studies that included more than 900 people with type 2 diabetes. The studies looked at the role of aerobic or resistance training (workouts such as weightlifting) in boosting the health of diabetics. Compared with either aerobic or resistance training alone, a regimen that combined both types of workouts was more effective in controlling blood sugar (glucose), blood fats, blood pressure and weight, the researchers said. The combination approach also helped more people reach higher levels of good cholesterol, according to the findings published July 2 in the journal Diabetologia. The Austrian researchers added that there is evidence that supervised ... Read more

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Insulin Pumps May Outperform Daily Injections for Type 2 Diabetes: Study

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – Insulin pumps provide better blood sugar control for adults with diabetes than multiple daily insulin injections, a new study says. Insulin pumps are small devices that are worn by patients and deliver constant amounts of insulin to the body through a catheter placed under the skin. The multicenter, international study was funded by medical device maker Medtronic and included 331 people aged 30 to 75. All of the patients had poorly controlled type 2 diabetes and were using multiple daily injections of insulin to control their blood sugar levels. The patients were randomly assigned to either continue using injections or to switch to an insulin pump. After six months, patients who used the insulin pumps had a much greater reduction in average blood sugar levels than those who used injections, the study found. According to the researchers, twice as many patients ... Read more

Related support groups: Diabetes, Type 2, Insulin, Lantus, Novolog, Humalog, Levemir, Lantus Solostar, Novolin R, Lantus Solostar Pen, Novolin N, Humulin N, Humulin R, NovoLog FlexPen, Humalog KwikPen, Humalog Pen, Apidra, Novolin 70/30, Insulin Glargine, Insulin Regular, NovoLog Mix 70/30

FDA Approves Afrezza to Treat Diabetes

Posted 2 Jul 2014 by Drugs.com

June 27, 2014 – The U.S. Food and Drug Administration today approved Afrezza (insulin human) Inhalation Powder, a rapid-acting inhaled insulin to improve glycemic control in adults with diabetes mellitus. Afrezza is a rapid-acting inhaled insulin that is administered at the beginning of each meal. An estimated 25.8 million (18.8 million diagnosed and 7.0 million undiagnosed) people in the United States or approximately 8.3 percent of the population–have diabetes. Over time, high blood sugar levels can increase the risk for serious complications, including heart disease, blindness and nerve and kidney damage. "Afrezza is a new treatment option for patients with diabetes requiring mealtime insulin," said Jean-Marc Guettier, M.D., director of the Division of Metabolism and Endocrinology Products in the FDA’s Center for Drug Evaluation and Research. “Today’s approval broadens the options ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus

Inhaled Medication Afrezza Approved to Treat Diabetes

Posted 30 Jun 2014 by Drugs.com

MONDAY, June 30, 2014 – An inhaled medication, Afrezza (human insulin), has been approved by the U.S. Food and Drug Administration to treat adults with diabetes. The rapid-acting, inhaled insulin is designed to be used within 20 minutes of beginning a meal, the agency said. Diabetes affects an estimated 25.8 million people in the United States, including 7 million who haven't been diagnosed, the FDA said in a news release. Serious complications could include heart disease, blindness and damage to the nerves and kidneys. Afrezza's safety and effectiveness were evaluated in clinical studies involving more than 3,000 people, of whom about two-thirds had type 2 diabetes and the rest had type 1 diabetes. The drug is not meant to replace long-acting insulin, and must be used in combination with long-acting insulin in people with type 1 disease, the FDA said. It should not be used to treat ... Read more

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FDA Approves Afrezza Inhaled Diabetes Medication

Posted 29 Jun 2014 by Drugs.com

SATURDAY, June 28, 2014 – People with type 1 or 2 diabetes now have a new means of getting their medication, with the U.S. Food and Drug Administration's approval on Friday of the first inhaled medicine for the blood sugar disease. The drug, Afrezza, "is a new treatment option for patients with diabetes requiring mealtime insulin," Dr. Jean-Marc Guettier, director of the Division of Metabolism and Endocrinology Products in the FDA's Center for Drug Evaluation and Research, said in an agency news release on Friday. He said that Afrezza's approval "broadens the options available for delivering mealtime insulin in the overall management of patients with diabetes who require it to control blood sugar levels." Diabetes falls into two main categories: type 1, an autoimmune illness which is often inherited and involves a dysfunction of insulin-producing cells in the pancreas; and type 2, ... Read more

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FDA Medwatch Alert: Olmesartan: Drug Safety Communication - FDA Review Finds Cardiovascular Risks for Diabetics Not Conclusive

Posted 24 Jun 2014 by Drugs.com

Includes: Benicar, Benicar HCT, Azor, Tribenzor, and Generics [Posted 06/24/2014] ISSUE: FDA has completed its safety review and has found no clear evidence of increased cardiovascular risks associated with use of the blood pressure medication olmesartan in diabetic patients (see previous alerts linked below). FDA believes the benefits of olmesartan in patients with high blood pressure continue to outweigh the potential risks. BACKGROUND: FDA safety review was prompted by the results of the ROADMAP trial. The ROADMAP (Randomized Olmesartan and Diabetes Microalbuminuria Prevention) clinical trial examined the effects of olmesartan in patients with type 2 diabetes, to see whether olmesartan could delay kidney damage. There was an unexpected finding of increased risk of cardiovascular death in the olmesartan group compared to the group taking a placebo, or sugar pill. However, the risk ... Read more

Related support groups: Diabetes, Type 2, Benicar, Azor, Benicar HCT, Olmesartan, Tribenzor, Amlodipine/hydrochlorothiazide/olmesartan, Amlodipine/Olmesartan, Hydrochlorothiazide/Olmesartan

Gut Microbes Differ in Obese or Diabetic People, Study Finds

Posted 23 Jun 2014 by Drugs.com

MONDAY, June 23, 2014 – Obese people and those with type 2 diabetes have lower levels of common types of "good" intestinal bacteria than healthy people, a new study reveals. The findings may be important, because measuring populations of these bacteria and other microscopic organisms in the intestines could help spot people at risk for obesity and diabetes, or the bacteria might offer targets for treating these conditions, the researchers said. The study was presented Sunday at the annual joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago. "Further studies should be carried out to elucidate if the gut microbial changes are a cause or effect of metabolic diseases," study lead investigator Dr. Yalcin Basaran, an endocrinologist from Gulhane Military Medical Academy School of Medicine in Ankara, Turkey, said in a meeting news release. ... Read more

Related support groups: Obesity, Diabetes, Type 2

People With Heart Disease, Diabetes May Be More Likely to Stay on Statins

Posted 23 Jun 2014 by Drugs.com

MONDAY, June 23, 2014 – People who have heart disease or diabetes, the overweight or obese and former smokers are most likely to keep taking cholesterol-lowering statins, a new study finds. Previous research has shown that as many 46 percent of patients who are prescribed statins stop taking them. Nearly one in 10 cardiovascular events are linked to failure to take prescribed drugs, according to background information in the study. Researchers looked at a group of people from Finland who began taking statins between 1998 and 2010. The people most likely to stop taking statins were women, single people and those aged 24 to 50. People without heart disease or diabetes were less likely to continue taking statins than those with the conditions. Among patients without heart disease or diabetes, those who were most likely to continue taking statins were overweight/obese or former smokers. ... Read more

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Health Tip: Helping Somone With Diabetes

Posted 23 Jun 2014 by Drugs.com

-- A friend or loved one who is struggling to manage diabetes may appreciate your help in achieving his or her goals. The National Diabetes Education Program suggests how to offer help to a friend or loved one with the disease: Ask the person if he or she ever feels sad or overwhelmed about having diabetes. Ask if the person has established goals to help control diabetes. Ask what may be interfering with managing diabetes well. Ask what you can do to help. Ask if the person has talked to a healthcare team about achieving goals and solving problems. Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1

Diabetes Distress Is Distinct From Depression, Researchers Say

Posted 16 Jun 2014 by Drugs.com

MONDAY, June 16, 2014 – Although diabetes distress is often mistaken for depression, the good news is that simple interventions appear to help significantly reduce this distress, according to new research. The need to correctly identify depression is also highlighted in a second new study. This concluded that people with type 1 diabetes who are also depressed have a higher risk of dying early compared to those who aren't depressed. Both studies were scheduled for presentation this week at the American Diabetes Association's annual meeting in San Francisco. Because the research hasn't been published in a peer-reviewed medical journal, it should be considered preliminary. "We're trying to make a distinction between diabetes distress and depression. Having some level of distress is part of the spectrum of diabetes," said the author of the first study, Lawrence Fisher, a professor of ... Read more

Related support groups: Depression, Diabetes, Type 2

Blacks May Respond Better Than Whites to Diabetes Drug Metformin

Posted 12 Jun 2014 by Drugs.com

THURSDAY, June 12, 2014 – Blacks with type 2 diabetes may fare better on the widely used drug metformin compared with whites, a new study finds. Researchers analyzed data from more than 19,600 Americans who were prescribed metformin between 1997 and 2013. The team found that blacks had greater improvements in their blood sugar control than whites. Study participants underwent at least two A1C blood tests at least four months apart while they took metformin. An A1C test measures a person's average blood sugar level over the previous three months. The maximum dose of metformin was associated with a 0.9 percent decrease in A1C results among blacks, compared with a 0.42 percent decrease among whites – a significant improvement. The study is published online June 12 in the Journal of Clinical Endocrinology & Metabolism. "Metformin is normally the first treatment physicians prescribe for ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet

Weight-Loss Surgery May Ease Type 2 Diabetes Long-Term

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – New research finds that weight-loss surgery is more helpful to obese patients with type 2 diabetes over the long term than regular care is. "This important study demonstrates what many of us in weight-loss surgery have suspected for years: That for those who are suffering from diabetes and severe obesity, weight-loss surgery and a healthy lifestyle works better to control these diseases than medical care alone," said Dr James McGinty, chief of the division of minimally invasive and baratric surgery at Mount Sinai St. Luke's and Mount Sinai Roosevelt Hospitals, in New York City. He was not involved in the new research. As obesity rates in the United States continue to rise, so do rates of obesity-linked type 2 diabetes. For years, improved diet, lifestyle changes and certain weight-loss medications were thought to be the only way to help obese diabetics slim ... Read more

Related support groups: Diabetes, Type 2, Gastric Bypass Surgery

Gene May Boost Chances of Type 2 Diabetes for Latinos

Posted 10 Jun 2014 by Drugs.com

TUESDAY, June 10, 2014 – A new study links a gene variant found in Latinos to a fivefold increase in the risk of type 2 diabetes, potentially explaining why the condition is especially common in Latino people. In Mexico, for instance, an estimated 14 percent of adults had type 2 diabetes in 2006. The condition is also common among Latino people worldwide. In the new study, researchers studied DNA samples from almost 3,800 Latinos – including Latinos from the United States and Mexicans – who were recruited from 1993 to 2013. Of the participants, about 1,800 had type 2 diabetes and the rest, nearly 2,000 people, did not. One type of DNA found from this group was further tested in a group of more than 14,000 people. This rare genetic variant was found in slightly over 2 percent of those with type 2 diabetes and just 0.36 percent of those without diabetes. That means that the gene was ... Read more

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