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U.S. Sees Drop in Deaths Linked to Diabetes

Posted 5 days ago by Drugs.com

TUESDAY, May 22 – Healthier lifestyles and better disease management led to a sharp drop in death rates for Americans with diabetes between 1997 and 2006, especially deaths caused by heart disease and stroke, a new federal government report shows. During that time, deaths from all causes for Americans with diabetes fell by 23 percent and deaths caused by heart disease and stroke in this group declined by 40 percent, according to the analysis of 1997-2004 National Health Interview Survey data on nearly 250,000 adults. One expert said the findings were reason for hope. "The encouraging news that less diabetic patients are dying from heart disease and stroke is a testament to multiple factors that have changed the playing field," said Dr. Tara Narula, a cardiologist at Lenox Hill Hospital in New York City. The study was conducted by researchers at the U.S. Centers for Disease Control and ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Ischemic Stroke, Diabetes, Type 1, Diabetes Mellitus

Middle-Aged Diabetics May Need Earlier Colon Checks

Posted 5 days ago by Drugs.com

TUESDAY, May 22 – Researchers who say they've linked type 2 diabetes with earlier development of precancerous colon lesions recommend people with the blood sugar disorder start colorectal screenings at a younger age than others. "Based on our data, it implies that people with diabetes should get screenings earlier, possibly at age 40, rather than at age 50," said Dr. Hongha Vu, a clinical gastroenterology fellow at Washington University in St. Louis. However, another expert said more research is needed before making that recommendation. Also, the researchers cautioned that they can't say for sure that diabetes by itself raises the risk of the precancerous lesions and further study is required. Experts know that diabetes is linked with an increased risk of colon and other cancers. Vu's team set out to determine if people with diabetes develop precancerous lesions, also called polyps or ... Read more

Related support groups: Diabetes, Type 2, Colorectal Cancer, Familial Adenomatous Polyposis

Diabetes Can Take a Toll on Your Emotions

Posted 10 days ago by Drugs.com

THURSDAY, May 17 – Many people know diabetes – both type 1 and type 2 – can take a serious toll on physical health. But these blood-sugar disorders also can affect your emotions and, in turn, your emotions can wreak havoc on your diabetes control. Extremes in blood-sugar levels can cause significant mood changes, and new research suggests that frequent changes in blood-sugar levels (called glycemic variability) also can affect mood and quality of life for those with diabetes. Depression has long been linked to diabetes, especially type 2. It's still not clear, however, whether depression somehow triggers diabetes or if having diabetes leads to being depressed. More recent research in people with type 1 diabetes has found that long periods of high blood-sugar levels can trigger the production of a hormone linked to the development of depression. People with type 1 diabetes no longer ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1

Could Eating Fast Increase Diabetes Risk?

Posted 19 days ago by Drugs.com

TUESDAY, May 8 – Eating too quickly may raise your risk of diabetes, a small, preliminary study suggests. Researchers from Lithuania compared 234 people with type 2 diabetes and 468 people without the disease and found that those who gobble down their food were 2.5 times more likely to have diabetes than those who take their time while eating. Study participants with diabetes also were more likely to have a higher body-mass index (a measurement of body fat based on height and weight), and to have much lower levels of education than those without diabetes, the researchers said. The findings were set for presentation this week at the joint International Congress of Endocrinology and European Congress of Endocrinology in Florence, Italy. "The prevalence of type 2 diabetes is increasing globally and becoming a world pandemic," study leader Lina Radzeviciene, of the Lithuanian University of ... Read more

Related support groups: Diabetes, Type 2

Two-Drug Therapy Helped Kids With Type 2 Diabetes

Posted 29 Apr 2012 by Drugs.com

SUNDAY, April 29 – Children with type 2 diabetes may achieve better blood sugar control with a combination of two drugs, metformin and Avandia, than with metformin alone, a new study suggests. However, Avandia (rosiglitazone) was recently linked to an increased risk of heart attack and stroke, so it may not be the best drug for these young patients, experts say. "Many kids with type 2 have a rapidly progressive disease requiring early onset of insulin therapy, and current approaches to oral therapy may be inadequate," said lead researcher Dr. Philip Zeitler, a professor of medicine at the University of Colorado, Denver. Zeitler noted that the choice of Avandia as a companion medication was made in 2002, before the cardiac problems with the drug were known. "Given the problems with rosiglitazone, we are not recommending it at this time," he said. "However, no problems with rosiglitazone ... Read more

Related support groups: Diabetes, Type 2, Metformin, Glucophage, Avandia, Glucophage XR, Glumetza, Riomet, Fortamet, Rosiglitazone

Value of Metformin, Insulin Combo for Type 2 Diabetes Questioned

Posted 19 Apr 2012 by Drugs.com

THURSDAY, April 19 – It's not clear whether patients with type 2 diabetes gain any long-term benefit from taking the blood sugar-lowering drug metformin and insulin together rather than insulin alone. That's the conclusion of Danish researchers who reviewed data from 23 clinical trials involving more than 2,200 patients over the age of 18. Reporting online April 19 in the BMJ, they found that taking metformin plus insulin leads to better blood sugar control, less weight gain and less need for insulin. However, the researchers also noted that the clinical trials provided little information about long-term patient outcomes, such as the total numbers of deaths and deaths from cardiovascular disease. This means that more clinical trials are needed to determine the long-term benefits and harms of the combination, specifically the risks of premature death. The researchers, led by Bianca ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Glucophage, Humalog, Novolog, Lantus Solostar, Levemir, Novolin R, Lantus Solostar Pen, Humulin R, Novolin N, Humulin N, Glucophage XR

Diabetes Groups Issue New Guidelines on Blood Sugar

Posted 19 Apr 2012 by Drugs.com

THURSDAY, April 19 – Type 2 diabetes is a complex metabolic disorder, and treating the disease often requires a personalized, multi-pronged approach, say new expert guidelines on treating high blood sugar levels, issued Thursday. The recommendations are a joint effort by the American Diabetes Association and the European Association for the Study of Diabetes. "We're making a lot of progress in managing type 2 diabetes," said Dr. Vivian Fonseca, president of medicine and science for the American Diabetes Association. "The new guidelines are more patient-centered. The message is to choose an appropriate [blood sugar] goal based on the patient's current health status, motivation level, resources and complications." "It is very possible to manage type 2 diabetes well and keep blood sugar under good control," he noted. "It's important that patients have a discussion with their doctor about ... Read more

Related support groups: Diabetes, Type 2

More Smog Might Mean More Hospitalizations

Posted 18 Apr 2012 by Drugs.com

WEDNESDAY, April 18 – Long-term exposure to fine-particle air pollution may increase older adults' risk of being hospitalized for lung and heart disease, stroke and diabetes, a new study says. Harvard School of Public Health researchers compared air-quality data with hospital admission records on all Medicare patients aged 65 and older admitted to 3,000 New England hospitals between 2000 and 2006. The researchers focused on fine air particles known as PM2.5, which have a diameter of 2.5 microns or less and are narrower than the width of a human hair. These particles – emitted by vehicles, power plants, wood-burning devices and some industrial processes – can lodge in the lungs and cause inflammation throughout the body. "Our study found that long-term rates of admissions for pneumonia, heart attacks, strokes and diabetes are higher in locations with higher long-term average particle ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Asthma, Ischemic Stroke, Chronic Obstructive Pulmonary Disease, Respiratory Tract Disease

Weight-Loss Surgery Beat Drugs for Cutting Diabetes in Very Obese

Posted 16 Apr 2012 by Drugs.com

MONDAY, April 16 – A bariatric surgical procedure is more likely than medicine to improve or even reverse type 2 diabetes in very obese patients, a new small study indicates. Italian researchers compared standard diabetes medicine with a surgical procedure known as the laparoscopic sleeve gastrectomy, and while 80 percent of those treated with the surgery had remission of their diabetes within 18 months, none of those treated with medicine did. "In our opinion, 80 percent diabetes resolution is a dramatically excellent result, compared with results of a medical approach in which there's not diabetes resolution," said lead researcher Dr. Nicola Basso, a professor of surgery at the University of Rome, Sapienza. All of those who had surgery and had diabetes less than 10 years reversed it, Basso said. The study appeared online April 16 in the Archives of Surgery. In the procedure, doctors ... Read more

Related support groups: Obesity, Diabetes, Type 2, Gastric Bypass Surgery

Common Plastics Chemical Might Boost Diabetes Risk

Posted 12 Apr 2012 by Drugs.com

THURSDAY, April 12 – High blood levels of chemicals called phthalates, which are found in soaps, lotions, plastics and toys, may double the risk for type 2 diabetes among older adults, Swedish researchers say. "Our study supports the hypothesis that certain environmental chemicals can contribute to the development of diabetes," said lead researcher Monica Lind, an associate professor of environmental medicine in the section for occupational and environmental medicine at Uppsala University. "Most people come into daily contact with phthalates as they are used as softening agents in everyday plastics and as carriers of perfumes in cosmetics and self-care products," she added. The study's implications "must be to cut down on plastics and choose self-care products without perfumes," Lind said. But the research does not prove cause and effect. To find out whether phthalates (pronounced THAL ... Read more

Related support groups: Diabetes, Type 2

Mouse Study Hints at New Path for Diabetes Treatment

Posted 12 Apr 2012 by Drugs.com

THURSDAY, April 12 – A potential new treatment for type 2 diabetes targets the hormone glucagon instead of insulin, according to a new study in mice. Although the research hasn't yet progressed past animal models of the disease, initial results suggest that the novel therapy can lower blood sugar, decrease insulin resistance, lower cholesterol and help keep fatty deposits from settling in the liver. What's more, the researchers didn't see any adverse effects from the treatment. "A new target for the adverse effects of glucagon on diabetes has been identified, and with treatment we got rid of all the bad stuff, but didn't cause side effects," said the study's lead author, Dr. Ira Tabas, a distinguished professor of medicine at Columbia University Medical Center, in New York City. Results of the study are published in the April 12 online edition of Cell Metabolism. Glucagon is a hormone ... Read more

Related support groups: Diabetes, Type 2

Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study

Posted 11 Apr 2012 by Drugs.com

WEDNESDAY, April 11 – Sleep deprivation, in combination with disrupted "body clock" rhythms, could result in some of the changes to a person's metabolism that can foreshadow both obesity and diabetes, researchers report. Participants in the small study who were only allowed to sleep about six hours a night and who were subjected to shifting sleep-wake cycles had higher blood sugar levels and lower resting "metabolic rates," which is a term that describes how quickly your body burns calories for energy. Elevated blood sugar levels can lead to diabetes. If diet and exercise aren't changed, low resting metabolic rates can lead to obesity, which in turn elevates the risk for diabetes. Previous research has shown that people who work the night shift or who continually get too little sleep have high fat levels in the blood and are more likely to be obese and have type 2 diabetes and ... Read more

Related support groups: Sleep Disorders, Obesity, Diabetes, Type 2

Victoza Label Updated to Include Data Showing Superior Efficacy When Compared to Januvia

Posted 9 Apr 2012 by Drugs.com

Princeton, N.J. (April 9, 2012) /PRNewswire/ - Novo Nordisk received approval from the U.S. Food and Drug Administration (FDA) to update the product label for Victoza (liraglutide [rDNA origin] injection) to include data showing superior blood sugar control when compared to Januvia (sitagliptin). Victoza also provided greater weight reduction. Both products were taken in combination with metformin in adults with type 2 diabetes. The update also includes data demonstrating the safety and efficacy of adding basal insulin to Victoza and metformin for the treatment of adults with type 2 diabetes. “We’re pleased to expand the Victoza product label to include data demonstrating superior efficacy over Januvia, said Camille Lee, Corporate Vice President, Diabetes Marketing at Novo Nordisk. “The additional data supporting combination therapy with basal insulin further demonstrates that Victoza is ... Read more

Related support groups: Diabetes, Type 2, Victoza, Januvia, Liraglutide, Sitagliptin

Climate Change Could Be Tough on Seniors' Health: Study

Posted 9 Apr 2012 by Drugs.com

MONDAY, April 9 – Even small swings in temperatures could put elderly people with chronic illnesses such as diabetes, heart failure and lung disease at greater risk of death throughout the coming summer, a new study indicates. Researchers from the Harvard School of Public Health in Boston found temperature fluctuations related to climate change could claim thousands of lives every year. Experts predict climate change could increase variations in summer temperatures, particularly in the mid-Atlantic states and in parts of France, Spain and Italy. In these more volatile regions, this could pose a serious public health risk, the study authors claimed. "The effect of temperature patterns on long-term mortality has not been clear to this point. We found that, independent of heat waves, high day-to-day variability in summer temperatures shortens life expectancy," study author Antonella ... Read more

Related support groups: Diabetes, Type 2, Asthma, Chronic Obstructive Pulmonary Disease, Congestive Heart Failure, Heart Failure, Diabetes, Type 1, Diabetes Mellitus, Respiratory Tract Disease

FDA Approves Levemir Pregnancy Category Change for Women with Diabetes

Posted 2 Apr 2012 by Drugs.com

Princeton, N.J. (April 02, 2012) /PRNewswire/ — Novo Nordisk, a world leader in diabetes care, announced today that the U.S. Food and Drug Administration (FDA) has approved Levemir (insulin detemir [rDNA origin] injection) for a pregnancy Category B classification, indicating that Levemir, when used in pregnant women with diabetes, did not increase the risk of harm to the unborn baby. The label update makes Levemir the first and only basal insulin analog to have this classification. Until this decision, NPH (human insulin) was considered the standard of care for diabetes in pregnancy. Now, Novo Nordisk is the only company that offers a complete portfolio of insulin analogs with a pregnancy Category B classification. The FDA category change was based on a review of a large, randomized controlled trial examining Levemir in pregnant women with type 1 diabetes. The study compared the safety ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Levemir, Diabetes Mellitus, Insulin Detemir

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