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Related terms: Carcinoma, Malignant Disease, Malignant Tumor

Taking St. John's Wort for Depression Carries Risks: Study

Posted 1 day 15 hours ago by Drugs.com

WEDNESDAY, July 29, 2015 – St. John's wort is a popular herbal therapy for depression, but a new Australian study highlights the fact that "natural" does not always equal "safe." Using reports filed with Australia's drug safety agency, the researchers found that adverse reactions to St. John's wort were similar to those reported for the antidepressant fluoxetine – better known by the brand name Prozac. Those side effects included anxiety, panic attacks, dizziness, nausea and spikes in blood pressure, the researchers reported in the July issue of Clinical and Experimental Pharmacology and Physiology. "It's concerning to see such severe adverse reactions in our population, when people believe they are doing something proactive for their health with little risk," lead researcher Claire Hoban, of the University of Adelaide, said in a university news release. Research has shown that St. ... Read more

Related support groups: Depression, Birth Control, Bipolar Disorder, Contraception, Lexapro, Zoloft, Cancer, Prozac, Skin Rash, Celexa, Paxil, Citalopram, Sertraline, Fluoxetine, Major Depressive Disorder, HIV Infection, Escitalopram, Paroxetine, Luvox, Dysthymia

FDA Medwatch Alert: Adrucil (fluorouracil injection, USP) 5 g/100 mL (50 mg/mL) by Teva Parenteral Medicines: Recall - Particulate Matter

Posted 3 days ago by Drugs.com

[Posted 07/27/2015] ISSUE: Teva Parenteral Medicines announced a voluntary recall of six lots of Adrucil (fluorouracil injection, USP) 5 g/100 mL (50 mg/mL) due to the potential presence of particulate matter identified as aggregate of silicone rubber pieces from a filler diaphragm and fluorouracil crystals. Administration of an intravenous product with particulate matter has the potential to result in inflammation, allergic reactions, or blockage of blood vessels, leading to tissue death, which may be life-threatening if vital organs are affected. To date, Teva has not received any reports of adverse events related to this recall. See the press release for product lot numbers affected by this recall. BACKGROUND: Adrucil Injection is used in the palliative management of carcinoma of the colon, rectum, breast, stomach and pancreas and is packaged in pharmacy bulk packages. ... Read more

Related support groups: Cancer, Fluorouracil, Adrucil

Many Young Cancer Patients Unaware of Fertility Preservation Options

Posted 4 days ago by Drugs.com

MONDAY, July 27, 2015 – Many young cancer patients – especially females – have limited awareness about options to preserve their fertility, a new study shows. Cancer and cancer treatments may leave some people infertile, making it important for young patients and their doctors to discuss the issue and ways to deal with it, the study published online July 27 in the journal Cancer noted. Researchers gave questionnaires to almost 500 teens and young adults who were diagnosed with cancer in 2007 or 2008. More than 70 percent were told that cancer treatment may affect their fertility, the study found. But males were more than twice as likely as females to say that they discussed options with their doctor. Nearly one-third of males said they made arrangements to preserve their fertility. That rate is four to five times higher than among females, the researchers said. Other factors that ... Read more

Related support groups: Birth Control, Contraception, Cancer, Female Infertility, Primary Ovarian Failure

Many Cancer Survivors Who Smoke See Little Benefit to Quitting

Posted 7 days ago by Drugs.com

THURSDAY, July 23, 2015 – Cancer survivors who continue to smoke view the habit as less risky than survivors who quit, and they're more likely to spend time with smokers, a new study shows. Researchers from the American Cancer Society also found that these post-cancer smokers are more inclined than others to raise obstacles to quitting. Not smoking is particularly important for people with cancer. These survey findings could improve strategies to help cancer survivors conquer their addiction, the researchers suggested. Doctors may want to encourage the relatives of cancer survivors to quit smoking to reduce their cigarette exposure and improve their odds of quitting successfully, the researchers said. "The association between smoking and exposure to others' smoke was particularly eye-opening," said study leader Lee Westmaas, of the cancer society's behavioral research center. "Being ... Read more

Related support groups: Cancer, Smoking, Smoking Cessation

Chemo May Worsen Quality of Life for End-Stage Cancer Patients

Posted 8 days ago by Drugs.com

THURSDAY, July 23, 2015 – Chemotherapy may worsen quality of life for some cancer patients who are nearing death, a new study finds. "Oncologists may presume there to be no harm in giving dying patients chemotherapy, but these data point to more harm than benefit," study author Dr. Holly Prigerson, from Weill Cornell Medical College in New York City, said in a college news release. The research included more than 300 patients with advanced cancer who had about four months to live. Their average age was about 59. About half of the patients were receiving what's known as palliative chemotherapy when the study began. Palliative chemotherapy is generally given to people who have fewer than six months to live, according to the researchers. The hope is that palliative chemotherapy will ease symptoms and extend survival. But that wasn't the case for those patients who started the study with ... Read more

Related support groups: Cancer, Breast Cancer, Metastatic, Nausea/Vomiting - Chemotherapy Induced, Breast Cancer - Palliative, Hyperuricemia Secondary to Chemotherapy, Neutropenia Associated with Chemotherapy, Anemia - Chemotherapy Induced

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 8 days ago by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Lupron, Accutane, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Tretinoin, Gleevec, Fluorouracil, Rituxan, Colorectal Cancer, Zoladex, Lung Cancer

Cancer Trials Need to Include More Seniors: Experts

Posted 11 days ago by Drugs.com

MONDAY, July 20, 2015 – Clinical trials of cancer treatments need to include more elderly people, a leading group of cancer specialists says. In a position statement released July 20, the American Society of Clinical Oncology called on the U.S. government and the cancer research community to broaden clinical trials to include older adults. "Older people living with cancer often have different experiences and outcomes in their treatment than younger cancer patients," Dr. Julie Vose, society president, said in a news release from the group. "As we age, for example, the risk of adverse reactions from treatment significantly increases. Older adults must be involved in clinical trials so we can learn the best way to treat older cancer patients resulting in improved outcomes and manageable toxicity," she explained. More than 60 percent of cancers in the United States occur in people aged 65 ... Read more

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Activity in Genes, Immune Cells Tied to Cancer Survival in Study

Posted 11 days ago by Drugs.com

MONDAY, July 20, 2015 – A cancer patient's chances of survival seem to depend partly on activity in specific genes and immune system cells, a new study suggests. Using data from nearly 18,000 people who were treated for cancer, scientists found that particular patterns of gene activity corresponded to patients' survival odds – across a whole range of cancers, including brain, breast, colon and lung cancers. What's more, the particular mix of immune system cells within patients' tumors also correlated with their prognosis, the investigators found. The researchers said the findings, published online July 20 in Nature Medicine, could eventually be used to find new targets for cancer therapies – or to help predict patients' chances of responding to some existing treatments. The discoveries have been compiled in a database that's available to other researchers, said senior study author ... Read more

Related support groups: Cancer

Insured Americans Up to 3 Times Likelier to Get Preventive Care: CDC

Posted 14 days ago by Drugs.com

THURSDAY, July 16, 2015 – Americans are up to three times more likely to receive preventive care for potentially fatal chronic diseases if they have health insurance, federal officials reported Thursday. Insurance provided across-the-board improvement in the number of people receiving any one of nine important clinical preventive services, researchers from the U.S. Centers for Disease Control and Prevention found. The type of health insurance doesn't matter. People paying for private insurance received the same preventive care as people on Medicaid or Medicare, according to the findings published in the CDC's July 17 Morbidity and Mortality Weekly Report. "Having insurance was the most important factor, whether it was private or public insurance," said lead author Jared Fox, a CDC health scientist. Preventive care is available for nine of the 10 leading causes of death in the United ... Read more

Related support groups: Diabetes, Type 2, Cancer, Cardiovascular Risk Reduction, Breast Cancer, Prevention

More Evidence a Healthy Diet Can Lower Risks of Heart Disease, Cancer

Posted 16 days ago by Drugs.com

TUESDAY, July 14, 2015 – Eating a healthy diet was linked to lower death rates from heart disease, cancer and other diseases among low-income adults living in the southeastern United States, a new study reports. Previous studies have suggested that people with low incomes, particularly black men, have limited access to grocery stores and healthy foods, the researchers said. But few studies have examined the link between diet quality and disease-related deaths. "This is the first study to our knowledge reporting this association in a low-income population that largely comprises African Americans," the study's lead author, Dr. Wei Zheng, director of the Vanderbilt Epidemiology Center in Nashville, and chief of the division of epidemiology, said in a university news release. The take-home message: A better diet can help prevent illness "in this underserved population," said Zheng, who is ... Read more

Related support groups: Cancer, Heart Disease, Cardiovascular Risk Reduction

Too Much Sitting May Raise a Woman's Cancer Risk: Study

Posted 17 days ago by Drugs.com

TUESDAY, July 14, 2015 – Lots of time spent sitting may increase a woman's odds for cancer, but it does not seem to have a similar effect on men, a new study suggests. "Longer leisure time spent sitting was associated with a higher risk of total cancer risk in women, and specifically with multiple myeloma, breast and ovarian cancers. But sitting time was not associated with cancer risk in men," concluded a team led by Dr. Alpa Patel, who directs the Cancer Prevention Study-3 at the American Cancer Society. One doctor said the message from the study is clear. "Encouraging individuals across all categories of weight to reduce sitting time would have an impact on their physical activity, with beneficial effects on cancer and other chronic diseases," said Dr. Paolo Bofetta, a professor of preventative medicine at the Icahn School of Medicine at Mount Sinai, in New York City. Reported ... Read more

Related support groups: Cancer, Breast Cancer, Ovarian Cancer, Multiple Myeloma, Breast Cancer, Prevention

Young Adult Cancer Survivors More Likely to Be Hospitalized

Posted 17 days ago by Drugs.com

MONDAY, July 13, 2015 – Young adult cancer survivors are more likely to be hospitalized than people who never had cancer, a new study finds. Researchers analyzed data from more than 20,000 people in Ontario, Canada, who had their first cancer diagnosis between ages 20 and 44 and had lived at least five years cancer-free. They were compared with a control group of more than 100,000 young adults never diagnosed with cancer. Up to 20 years after being declared cancer-free, the overall hospitalization rate for cancer survivors was 1.5 times higher than for people in the control group, the researchers found. The rate of hospitalization was twice as high for survivors of gastrointestinal cancer, leukemia, bladder or kidney cancer, colorectal cancer, brain cancer and lymphoma, the study revealed. The study was published July 13 in the Journal of Clinical Oncology. "Even when young adults ... Read more

Related support groups: Cancer

Prenatal Gene Tests Can Sometimes Spot Cancer in Mom-to-Be

Posted 17 days ago by Drugs.com

MONDAY, July 13, 2015 – Abnormal results on noninvasive, prenatal genetic tests don't always indicate a problem with the fetus. In some cases, these tests may uncover maternal cancers, a new study reports. "If the test comes back abnormal, the patient should not panic," said study researcher Dr. Diana Bianchi, executive director of the Mother Infant Research Institute at Tufts Medical Center in Boston. "It doesn't necessarily mean anything is wrong with the fetus." In her study, 10 women had abnormal findings on a noninvasive prenatal test. A more invasive follow-up test found normal results for the fetus, but the test also revealed cancer in the mother. The findings, Bianchi said, point to the need to do further tests if the noninvasive blood test comes back positive. The chances of this happening are low, she said, but it's crucial to consider the possibility. "Cancer is not that ... Read more

Related support groups: Cancer, Diagnosis and Investigation

Cancer Survivors May Face More Challenges When Adopting

Posted 18 days ago by Drugs.com

MONDAY, July 13, 2015 – Cancer survivors may face roadblocks when trying to adopt children, a new study finds. Cancer and cancer treatments can leave some patients infertile, so many young cancer survivors turn to adoption when hoping to start, or add to, a family, the researchers noted. For the study, 71 oncology nurses in 15 states who were taking part in a training program were asked to gather information from adoption agencies. Not all of the adoption agencies recorded whether prospective parents were cancer survivors, but those that did keep such records had an average of 10 cancer survivors a year seeking to adopt. Some of the agencies said some birth mothers may be reluctant to have their baby adopted by a cancer survivor. But, most said that birth mothers might feel good about choosing an adoptive parent who has overcome cancer and has an appreciation for life, the study noted. ... Read more

Related support groups: Cancer, Female Infertility, Oligospermia, Primary Ovarian Failure

Online 'Symptom Checkers' Often Miss Diagnosis, Study Finds

Posted 9 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – Automated online "symptom checkers" that seem to offer patients a quick opportunity for self-diagnosis provide the right diagnosis in only about one-third of cases, a new analysis reveals. The study team found that online checkers – which are typically free services offered by medical schools, insurance companies, and even government entities – are a more reliable and effective means to get a handle on symptoms than using web search engines such as Google. The investigation also found that online medical checkers are about as accurate as primary care physician phone services that offer patients advice on whether or not a condition requires urgent care. "The goal with these symptom checkers is to try and streamline the process by which people search the Internet for information on health problems," explained study lead author Hannah Semigran, a research ... Read more

Related support groups: Cancer, Heart Disease, Influenza, Atrial Fibrillation, Angina, Cold Symptoms, Pre-Diabetes, Diabetes Mellitus, Ischemic Heart Disease

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