I had a recent increase in my psychiatric medication Seroquel and I bloated and swelled which I never did even as a pregnant woman years ago, so I took my spironolactone AKA Aldactone for a week, but by the time I was done and realized my pain was greater than when I started ( I have chronic pain syndrome), I've been off of it now for a week and yet my pain is still off the charts in my bones and muscles. I asked my doctor and he just brushed It off saying it was my chronic pain but I know it's much worse now before I took the medication Aldactone for the fluid retention. He also completely discounted the possibility of the Seroquel causing the water weight gain telling me to stop eating so much, and I was very hurt because I eat very little, the pain I have makes me not hungry, and I was hurt by his reaction.