6 Jan 2013
Hello kit843 & welcome to the site. If you are having liver problems oxycodone is not the best med to be taken. I am copying part of whta the FDA monograph has to say bout it to get it right:
Extensively metabolized in the liver to noroxycodone and oxymorphone and their glucuronide conjugates.
Oxymorphone formation mediated by CYP2D6;g approximately 10 times as potent as morphine parenterally and likely contributes to oxycodone’s effects.g
Oxycodone and its metabolites excreted principally in urine.
Conventional preparations: 3.2–5 hours.b g
Extended-release tablets (e.g., OxyContin): apparent half-life 4.5–8 hours.g
Renal impairment: elimination half-life increased by 1 hour compared with normal renal function.g Peak plasma concentrations and AUCs for oxycodone and noroxycodone increased substantially.g
Mild to moderate hepatic impairment: the elimination half-life was increased by 2.3 hours compared with normal hepatic function.g Peak plasma concentrations and AUCs for oxycodone and noroxycodone increased but less substantially than with hepatic impairment.g
Wishing you the best...
- Oxycodone Information for Consumers
- Oxycodone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Oxycodone (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
My Dr. wants to take blood tests every 6 months to see if I have liver damage and I don't see that listed as a side effect.
1 answer • 12 Sep 2009
3 answers • 10 Jul 2010
I heard that a side effect could be liver damage. I am experiencing liver pain and lower back pain. Been on the drug over a year and haven't ...
4 answers • 2 Feb 2011
Ive been taking to ambien for quit a while and my stomach is killing me since i have liver problems already i want to know if there is side effects ...
1 answer • 15 Feb 2012
My husband has almost all of the side effects of Tramadol. I'm guessing 3/4s of them. The only thing I didn't see on there was anything ...
5 answers • 12 Nov 2014