I have gained 35 lbs in just over 7 months on Latuda. I also take Vivactil 10mg and Lithium 100mg daily. I have just tried Saphris with no appreciable results: no mood difference, restless for a few hours and a rash covering one side of my face that is still not resolved 5 days later. Does anyone have any experience with weight loss on an antipsychotic? Thanks!