25 Sep 2010
Nucynta (tapentadol) has an average elimination half life of approximately 4 hours.
It takes 5.5 x elimination half life's for a drug to be out of ones system, therefore it'll be in your system for at least 22 hours (5.5 x 4 hours). Since the elimination half life is an average value it is likely that it'll stay in some people's system for longer than that.
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