... my BP medication. At first it was only in the evening, and now it is 24/7 of constant cramping of every muscle below my knees! I've tried several medications, losartan, metoprolol, and lisinopril. Once I go off the medication, the cramping immediately stops. My doctor does not believe it is due to the PB medication, but it seems pretty obvious to me that it is. Has anyone else experienced this problem? Did you find a solution?