Is it OK to take glimepiride with Trulicity ?

Interactions between your selected drugs
Moderate
glimepiride dulaglutide
Applies to: glimepiride, Trulicity (dulaglutide)
Using glimepiride together with dulaglutide can increase the risk of hypoglycemia, or low blood sugar. You may need a dose adjustment or more frequent monitoring of your blood sugar to safely use both medications. Let your doctor know if you experience hypoglycemia during treatment. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Other drugs and diseases that your selected drugs interact with
glimepiride interacts with more than 400 other drugs and 5 diseases.
Trulicity (dulaglutide) interacts with more than 200 other drugs and 4 diseases.
Interactions between your selected drugs and food
Moderate
dulaglutide food
Applies to: Trulicity (dulaglutide)
Dulaglutide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.

https://www.drugs.com/interactions-check.php?drug_list=1176-0,3562-16895