For those who have been on Wellbutrin/Buproprion... can you rate your experience in the following areas and what dosage level you are on ? (1) motivation(feeling of getting things accomplished) (2) weight management - weight loss or weight gain (3) sex drive - increase or decrease ??
30 Jan 2013
Hi lowT-nice to meet you.
I switched to Viibryd from Wellbutrin/Buproprion after approximately 8 yrs. I felt like it was losing efficacy and my MD agreed.
With regard to your specific questions:
1) My productivity/motivation was initially improved. This is one of the main reasons I switched to another med-I began to feel low and unmotivated.
2) No weight gain or loss to speak of. Wellbutrin generally does not cause significant weight fluctuation, and is often the drug of choice because other anti-depressants are known for weight gain.
3) Sex drive was SIGNIFICANTLY reduced on Wellbutrin. I'm delighted that it has returned on Viibryd.
I'm sure you'll receive additional replies with varying experiences. Hope it's helpful.
This recent announcement may also be of interest to you:
4N Substances aka Frenchie
31 Jan 2013
I am on the maximum dose of bupropion, 450mgs daily. It helps with motivation and concentration. I have neither lost weight nor gained weight because of bupropion. I originally started the bupropion in hopes of it counteracting the lack of libido due to the other antidepressant I take. Didn't help.
2 Feb 2013
I've been on various antidepressants for the past 20 years. First switched between several SSRI meds, which always made me want to sleep all the time & eat everything in sight... plus ZERO sex drive. This led to weight gain among other problems, so my doc gradually added in Wellbutrin with my Zoloft. Eventually, taking me all the way off the Zoloft. The transition period was uncomfortable - shaky, nervous, trouble eating & sleeping - BUT this was over within a week or so. My doc gave me .5mg Xanax to take as needed up to 3 times a day, which took the edge off those initial symptoms, but really didn't need them for more than as couple weeks.
Now, to answer your questions:
1. I'm far more alert & better able to focus now, so I'd say it definitely positively affected my productivity. On SSRIs I seriously was ALWAYS sleepy.
2. DEFINITELY helped me lose weight! I had much more energy to exercise & had to remind myself to eat - especially at first. I lost about 40 lbs in the couple months after being on Wellbutrin alone.
3. While I can't say it INCREASED my sex drive, it DID take it back to NORMAL. The SSRIs totally KILLED it - I NEVER wanted sex. Now, I just feel a NORMAL, appropriate desire for sex.
I hope this helped in some way.
Btw - my dosage is currently 150mg in AM & 150mg in PM. I've been maintained on this dosage for about 14 years now.
5 Feb 2013
I started the generic form of welbutrin about 3 months ago and so far I have stayed stable at weight and the libido has elevated where it was nothing before :) so I can say that I am really happy with welbutrin the only thing that has been a pblm has been lack of sleep but thats still better then sleeping all the time as I had been on my other antidepressant.
16 Jul 2013
I have been on Wellbutrin for more than a decade. In my experience, it helps with the "can't get out of bed" kind of depression, but may not be good for the "high anxiety, irritable" kind of depression. It seems to increase anxiety a little, which keeps me active and motivated to accomplish things. I've lost weight only in the beginning weeks. Once you get used to it, your weight stabilizes, and you have to watch your diet once again. No effect on sex drive, but it can exacerbate relationship problems if you have anger management problems (like me). "Wellbutrin rage" may not be a documented side effect, but I really have to watch for it.
13 Mar 2014
I have been on Welbutrin since I was 15 on and off, depending on insurance and pregnancy. (Now am 28). I have nothing but positive things to say about it. I have always been able to maintain or lose weight on it. If I wanted to maintain, I would eat normal and snack lightly. To lose weight, watch what I eat and try not to snack. I have always been more motivated while on it and I have no problem at all with my sex drive :)
23 Jul 2014
Was on 450-600 mg for about three months. Doctor put me on it for a "zip" to start my day. It completely sedated me. Left me a lump on the couch not wanting to do anything at all. Sex drive completely diminished. Made me not want to eat (that has never happened before with anything!) Kept me awake all nite in bed tossing and turning.
Towards the end if my first month I started to eat again started to sleep again at night. It still didn't get me energy to want to leave the couch or move (usually I am a person that constantly needs to be moving and doing something) and never did get my sex drive back.
Very disheartening. Thought I would be like the norm and get some energy lighten my mood and enhance my sex drive. All opposite for me.
I tapered off on my own and quit for about two months. I started buproprion again an hour ago hoping it will work this time? Starting to feel depressed and grasping out of desparation.
3 Feb 2015
When I first started on Wellbutrin, I was already taking Lexapro but it stopped helping after a period of time and it caused me to gain a tremendous amount of weight so instead of upping my dosage, my Obgyn added Wellbutrin and told me the Wellbutrin would even out the weight gain from the Lexapro. I felt amazing after only a week of adding the Wellbutrin and it was at the lowest dosage of 150 mg but unfortunately my appetite stayed high and I was continuing to gain weight so I weened of the Lexapro and just stayed on the low dosage of Wellbutrin. After only a month though, I had to get the Wellbutrin raised to the second highest dosage which is 300 mg and it took about another month before I started to feel really good again. I have way more motivation now then I had when I was diagnosed with PPD and PTSD over 2 years ago. I even got motivated enough to finish college finally and it's going great! My sex drive has never really been an issue with anti depressants.
I still love having sex with my husband and I've had neither an increase or decrease in sex drive. As far as weight management goes, the Wellbutrin does decrease my appetite but it's not consistent; one day I'll be super hungry all day and then the next few days, I will feel slightly nauseous and have no desire to eat all day. Sometimes just looking at food will make my stomach turn on the days that I can't eat. I also want to add a question to this post however; does anyone else experience difficulty falling asleep even if you feel tired? My sleep patterns are insane on Wellbutrin. For days on end I can't fall asleep till 4 or 5 am and then I'm up and wide awake by 9 or 10 am but after several nights of that, then I'll have one night where I'm asleep by 10 pm and I don't wake up till 10 am the next day and then of course it starts back over. Does anyone else experience this somewhat vicious cycle?
29 Jun 2015
I'm on 300mg xl and it has actually been a life-changer. It's the only AD that I've found works for me.
1) It absolutely gives me energy and motivation, I can actually get out of bed in the morning--and don't dread it.
2) neutral. I haven't gained or lost any weight, or noticed any changes in my eating habits, even in the beginning.
3) It has decreased my sex drive (I'm female) not in a sense that I enjoy sex less (I still enjoy it in the moment) it's just that it's not as much of a priority for me.
9 Aug 2015
What most people don't realize is SDRI's usually take longer to kick in than SSRI's. They normally take between a week to anywhere over a month to start working properly. I've been on it before for several months and it tended to help a lot. I stopped for almost a year and have now started taking it again. I've been on it for about a week and can say that it isn't really affecting my sex drive in any way, it definitely improved my mood and has had no affect on my weight before or now, if anything it's helped me manage my time better and has helped me with my anxiety as well. Hope this helps!
31 Oct 2015
Well I was on 150 mg twice a day. Not a good medicine for me. I didn't notice a huge weight gain but I think with all the different types of meds I have taken sexual level has DRAMATICALLY DROPPED that it has caused problems in my marriage. I did have anger issues with while on it could not feel any other emotions I felt. I even burned my arm and didn't feel anything. Motivation was like I did not care if it happens or not. But the thing is that it may work differently on everyone.
19 Nov 2015
I started taking Welbutrin about a month and a half ago to help manage my feelings of grief and depression, which included lack of motivation, loss of interest, sleep disruption, and significant weight gain. Initally, I was taking 100mg/day and I found that in the first 2 weeks, everything was worse. I had no motivation, I was more irritable, sleep was still disrupted, and I was practically binge eating. At about the 2 week point, things began to level out and I was feeling better. However, my motivation was still lacking and so was my interest.
By the 1 month point, I asked my doctor to increase my dosage so I could get the push I needed each day. He increased to 200mg/day and I think that has been the perfect dose for me.I am pretty even emotionally each day and can focus much better. My motivation has improved, not to where I want it to be, but enough to make me feel good about getting up and going. Since starting wellbutrin, I've lost 11 pounds and I think it's because it is a very powerful appetite suppressant. For me, I believe this is connected to the main side effect I've had, which is dry mouth. This causes me to only want to drink water because food doesn't taste to same anymore. I only really enjoy it when I'm very well hydrated and even then, I feel full quicker and don't always finish my meal.
With regards to sex drive, I feel it is about the same or a little more increased. I desire it, but it's nothing too crazy, but it's definitely better and more satisfying than before starting the medication. Possibly because I don't feel the overwhelming feelings of grief and depression.
Overall, I think the motivation cant just come from the medicine, the person has to want it, too. So on those days where I make a plan about the things I want to do, I usually get up and do them. On days when I'm just lounging, I feel a bit anxious (maybe because the stimulant effect is not being effectively put into doing anything), which can feel overwhelming and make me not want to do much. Personally, I have been very satisfied with the effects and I think the higher the dosage, the more your natural ability to level out and work with the medication will be hindered or thrown off. My doctor said that being on the lowest dose that feels effective for you is the best option and, in my case, I greatly agree. Good luck to everyone out there!
18 Dec 2015
I've been on 300 mg of the generic Wellbutrin for almost a month now, before that 200 for a month and started at 100 so been on the medication total for almost 3 months. For me it hasn't really helped with motivation. Definitely reduced my appetite which only really kicked in once I was on 300 mg for a week or so. It's good for someone who overeats from depression in that way, so it was a positive side effect for me. As far as sex drive it has stayed mostly the same, if anything the medication has reduced it a little bit but not enough to be a problem.
For me it has helped a lot with anxiety, it keeps me calm and without episodes of being so stressed out and overwhelmed. But it does also make me feel kind of numb, like I used to cry pretty often and now I can't fully cry at all which is weird. You have to weigh whether you'd rather feel all the awful things and also some good things fully, which can be really bad at times with low points, against not feeling very much depth of emotion either way.
One other positive which I'm not really wanting to give up is that I'm better with people on it, probably from reducing anxiety because I always had social anxiety and was worried how I was coming across which made me nervous and awkward all the time. Meds like this seem to make a lot of people more anxious though, so my experience with it reducing that may be more of an outlier than a common observation
11 Jan 2016
I started taking Welbutrin 300 mg 2 and a half weeks now and feel amazing. I also take Abilify 10 mg. I was on Celexa for 4 months and hated it. I had no motivation, sleep 12 hours at night and could take a 3 hour nap. My doctor told me to ween off Celexa for a week while starting Welbutrin. Within the first day I felt better, no lie. I had no energy and felt very lazy before Welbutrin. I have worked out twice a day since I started and even have better concentration. Hadn't read a book in a year. Finished Keith Richards book Life in 9 days. I am hoping to lose weight too. Celexa caused me to put on 10 pounds. Welbutrin has mad me feel like a human being. Haven't felt so happy in ten years. I am diagnosed bipolar and had anxiety. I have no anxiety anymore. The only problem is,trying to stay asleep. I wake up all through the night but feel great in the morning.
9 Feb 2016
I was depressed for over a year before taking Wellbutrin. I'm a 58 year old woman who had a total hysterectomy at 48 years of age due to fibroids. In the past I took celexa and my HRT therapy, which did nothing but made me eat. I've only been on 75mg of Wellbutrin for 4 days now. No significant change. I've experienced for a long time, unmotivation, I have to be forced to take a shower. I'd rather do a sponge bath, self care is a challenge. Which is odd because I don't look my age, I had an active libido, exercised daily and dress like the the front cover of Vogue magazine. Now I have very little joy and very blah sex drive, some weight gain. Just hell on earth! I want to be hopeful that Wellbutrin will work for me. My Dr. Stated that she will increase after a month or include Effexor with this medication if no change. I so need something to work; anything. I'm so tired of this kind of life. Especially at my age. Not the way I want to roll in my later years.
- Wellbutrin Information for Consumers
- Wellbutrin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Wellbutrin (detailed)
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