I have trouble getting to sleep and staying asleep. Don't want to take anything that would be habit forming/dependency. Have just been prescribed 25 mg. at bedtime.
How effective is amitriptyline when used to help sleep?
Question posted by jbonderud on 16 Nov 2012
Last updated on 1 February 2023 by SonjaCarlton
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29 Answers

Amitriptyline is a prescription drug that's used to treat depression. Besides depression, amitriptyline can be used "off-label" to treat post-herpetic neuralgia, attention deficit hyperactivity disorder, certain eating disorders, to prevent migraines and to help with sleep problems (insomnia). Amitriptyline is also used to treat pain associated with a wide array of medical conditions. Off-label drugs are not FDA approved for alternative uses.
Amitriptyline is generally considered safe with low risk for long term use in patients with insomnia. It is particularly effective if the patient is also suffering from pain. Amitriptyline has a long half life which makes it useful for patients have trouble remaining asleep and wake early.
It is not suitable for patients with certain heart problems (arrhythmia), drug interactions, the elderly (because of risk of falls) and patients who are at high risk of overdose.
Amitriptyline is not habit-forming so it does have the potential to be a long term option for the treatment of insomnia.
For more information visit:
https://www.drugs.com/comments/amitriptyline/for-insomnia.html
https://www.drugs.com/health-guide/insomnia.html
https://www.drugs.com/amitriptyline.html
I love it and it is not habit forming. You do not have to take it every night. The pill put you to sleep slowly. It is not like some heavy narcotics that knocks you out quickly.
I was prescribed 10 mg of amitriptyline about eight years ago when my husband had terminal cancer. Early last year I had forgotten why I had been prescribed it & quite honestly forgot to renew my prescription but two days later I felt unwell, then was very sick. I managed to dial 999 then had seizure, coming round about three days later in hospital. When I put it together I told doctors and they saw fit to let me go home within a week, however they had upped the dosage to 25 mg. I have slowly got back down to 10 mg, am too scared to drop below that, I do have sleep issues but wouldn’t want to get too dependent on this drug because of my experience.
It doesn’t help me at all. It’s 4:30am here and I’m wide awake typing to you on my phone. Also I’m not sleepy during the day either, which is fine. But also messed up. Now I’m taking Ambien on top of the amitriptyline. mirtazapine and Seroquel worked much better for me.
I have been taking amitriptyline for over 15 years, I would wake up during the night and have trouble falling back to sleep. I always sleep great now. I have tried to see if I could stop taking it but my problems return.
Works very well for me 10mg at night. Takes 2-3 hours to work though. I take it for pain tho
I have taken amitriptyline for over 8 years when I started I couldn't sleep at all, I was given 150mg I fell right to sleep and slept until 3pm the next afternoon and had to be woke up I was still tired and wanted to go back to sleep but I got up. It took me awhile to get use to it but I was having trouble tripping, falling and one of my other doctors recommended me to cut the pill in half and only take 75mg. I did and it still works great. There is a couple other side effects I experience but I recently tried giving it up for a week and take a temazepan I dont think I spelled that right but its a sleeping pill, it had no effect on me I have been awake now for several nights, even though I don't like some of the other side effects I got to get back on it if I want to sleep. Some of you who say it doesn't work for you up your dose.
Ive been on amitriptyline for 10 days now to aid me with insomnia/depression. Im sleeping loads better now, Just on 20mg. The only thing that bothers me is the night sweats are unreal. Keep a glass of water beside your bed i wake 1s or twice in night for a drink
I was prescribed amitriptyline 25-75mg at night to aid with sleep. I could go to sleep with other sleep aids, but I would not stay asleep. I had tried OTC aids as well as trazodone. The amitriptyline worked wonders for me, but it does take the full 75mg to keep me asleep through the night. The plus side is that when I awake, my chronic back pain is more easily tolerated (DDD).
I was skeptical when my doc took me off Lunesta (it can cause memory loss). It took about 2 weeks for the Amitriptyline to kick in for sleep but it works well now. I only take 25 mg. When we thought that wasn't enough I went up to 50 mg. but it made me spaced out. I now feel sleepy at bedtime which I hadn't felt for a long time.
Well it works for some people I've been taking it for more than two years and I'm up to 75mg a nite plus another pill to help me rest better sometimes it works others I'm wide awake like a coffee drinker which I don't .I guess its all about how tired you are and how much wear and tear on ones body .but as for myself sometimes im still wide awake after taking this along with 10mg of melatonin also...
How long does amitriptylin work once you take it at night
I've been using amitriptyline hcl 50 for a month for sleep. The only thing it has done is interfere with my sexual ability. Anyone else have that issue?
I have been on it for a few years for IC. Most of the time it will put me to sleep. There have been times when it hasn't due to other medical issues I have. I have found that it causes me to have blackouts and the next morning I either can't remember or only get filters of what happened the night before.
Hm. I may be an outlier, but I tried it for about a year at a 50 mg. dose, and it did not help me sleep at all, and also, it gave me low blood pressure in the daytime, so I had to discontinue it eventually. I hope it works better for you!
Related topics
sleep disorders, amitriptyline, sleep
Further information
- Amitriptyline uses and safety info
- Amitriptyline prescribing info & package insert (for Health Professionals)
- Side effects of Amitriptyline (detailed)
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