I have been on Zoloft for 3 months now and feel too like it has changed my life. I take 25 mg a day, and no longer get nervous in groups of people or dread social situations. I'm also a lot nicer to my husband! I used to worry about EVERYTHING, but now I don't let things get me down. It's great. I can, however, feel some "twitching" (for lack of a better term) going on in my brain which makes me think about brain aneurysms. I"m curious about the long term effects of Zoloft use on the brain. Does anyone know?
2 Feb 2013
I have been on Zoloft for over15 years. I take 100 mg a day along with 1mg of Kolonopin. This drug has changed my life. No more panic attacks; choaking, etc. It think the only effect that I believe is due to the Zoloft is that I no longer have a good memory, but who knows, it could also be from getting older. I do have to take both drugs or I would shake from just the Zoloft.
4 Mar 2011
I have been put on zoloft and taken off over the years and even though it did seem to work in keeping me active and focused I dealt with alot of side effects from the drug... Insomnia, clenching teeth, a little nervous, extremely dialated pupils... rubbing and scratching at times and a few other's... I was then put on klonopin at one time .05 to offset the side effects and shaking from alcohol withdrawal, and then switched to diazepam. Zoloft is the only other psych med that I have been on for about as long as Celexa which I am on now and have been taking for about a year... The only way to see How you believe it will effect you is to give it 2-10 weeks and see how things go, if no, then speak with your doctor about swithching the medicine... blaze22
4 Mar 2011
Hi there happymomof2 I was on this drug for 8 years due to depression,anxiety and stress.The first few years it worked & helped mainly my depression due to stress, anyway as the years went by I noticed different side effects appear these are as follows !
itchy dry skin,stomake cramps,leg pains,weight gain, headakes,diarrhea everyday ,lack of sex drive, indigestion & reflux which was cronic bruising, also crying when stressed.I decided to go to my doctor because my life was out of control due to cronic anxiety & stress Zoloft was not helping so I then had to withdraw of the drug slowly over a period of nearly 3 weeks & then went onto a drug that has just had its second testing which found it to be very good at treating depression,anxiety & stress, the name of this drug is called Pristiq, I am now on the end of my second week using this drug.The only down side for me is the drug does not help me sleep my dose is low 50mg but I dont want to go any higher so have found a alternative product to aid my sleeping it is a herb called Valerian Fort which is for insomnia,I take the 1000 mg tablets x 2 at night 1 hour before going to bed ,works like a dream.I wish you well on the decision you make & hope my advice offers some help to you ! take care Candypq
4 Mar 2011
I'm pleased to here about your success with Zoloft. As far as the long term effects of taking Zoloft, the longest studies done to determine this were over 52 weeks. You can read about the common side effects by going to:
As with any antidepressant, how Zoloft actually effects the brain is not well understood. It controls the brain chemical serotonin in the brain synapsis from being uptaked by the receptors, therefore affecting mood and anxiety production. Why you are experiencing these "twitching" sensations is unclear to me. The possibility of a brain aneurysm is unfounded and probably nothing to worry about. If the symptom continues or becomes more bothersome, please contact your doctor.
You are on a low dose of Zoloft and are having excellent results, relax and enjoy!!
Keep in touch,
4 Mar 2011
Hey happymomof2, glad to hear the Zoloft is working for you. My husband is bi-polar manic depressed & thanks to a really good physciatrist & Zoloft he's still wilth me today. He takes 100mg, so yours is a low dose as LaurieShay pointed out. If you feel there may be a small side effect, you should take it up with your doctor as everyone reacts differently to different drugs. A phone call may put your mind at ease so you can go on being a happy mom! Lots of luck to you, & glad you are getting the help you richly & your kids deserve.
29 Apr 2013
I have been taking zoloft for 13+ years, I started on 25 mg, then 50, 100 and now I take 200 mg. I dont have any different side effects then I did when I first started taking it. The only thing now is if I skip it on accident that day, by night I feel off balance, where as before I would take 2 days.
- Zoloft Information for Consumers
- Zoloft Information for Healthcare Professionals (includes dosage details)
- Side Effects of Zoloft (detailed)
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