How does a doctor know when it is safe to get off Eliquis for dental work?

Most dental work is considered low risk. The official FDA and manufacturer's Prescribing Information is that ELIQUIS should be discontinued at least 24 hours prior to elective surgery or invasive procedures with a low risk of bleeding or where the bleeding would be non-critical in location and easily controlled. Bridging anticoagulation during the 24 to 48 hours after stopping ELIQUIS and prior to the intervention is not generally required. ELIQUIS should be restarted after the surgical or other procedures as soon as adequate hemostasis has been established. If your dentist is not willing to tell you if you should discontinue your ELIQUIS, you should ask your hematologist.