I have been on the generic Wellbutrin for depression for about 3 to 4 months now and have packed on a significant amount of weight. I cannot get enough sleep, but I notice that I toss and turn all night long. Has anyone else noticed that this is a side effect of the medicine?
24 Aug 2012
it's unusual to gain weight on wellbutrin. it actually is a med that is weight-neutral, so many drugs say they are weight-neutral but really are not. some people will only take wellbutrin because they don't gain weight on it.
all i can suggest for sleep is to take it in the morning. i take meds to sleep, so can't help you there.
24 Aug 2012
I have to agree with Briards. I take 100mg of Bupropion Sr twice daily. I started out taking plain Bupropion then went to Sr. I haven't experienced weight gain at all. In fact have lost a couple of pounds. I too take something for sleep too. If it is continuous and bothersome to you, talk to you're doc. and let him know. Pristiq is another one that is good and not supposed to cause weight gain either. It didn't for me anyways. Good luck to you, and take care. Ruthie
24 Aug 2012
Yes it did me. Im on bupropion 150 ER... I uzually wear a sz. 3... within 5 months I now wear 5-7... I have was a 3 all my life. Bupropion is the ONLY thing I have done different. Also since taking it I have become a bitch... after the 2nd month. I stopped taking it about 3 weeks ago feel much calmer. Bet it takes me a lot longe to get this weight off. Guess it affects ppl differently. I just use my xanex, which I have taken for a long time with no weight gain or lash outs.
25 Aug 2012
If it's not the Bupropion then maybe it could be the Abilify. Anyone have any negative encounters with this antidepressant. I started taking it just a month or so ago. Also, I was thinking about switching from the buprpion to celexa... Any thoughts about that concerning the weight gain in particular??
25 Aug 2012
I could NOT sleep when I tried Wellbutrin and I had terrible anxiety attacks on it as well. But no weight gain, in fact I believe I lost weight while on it. But that may have been due to having panic attacks, they truly make me lose my appetite.
Hope you find something that works, I switched to good old prozac and had a very good experience with it, no depression and no panic attacks.
Good luck to you
25 Jul 2013
I have been on Bupropion for several years and gained weight. I used to go to the gym three or four times a week and follow a moderate diet. That helped me lose 150 lbs. But a couple of years ago my arthritic knee caused me to stop doing regular exercise, and walking is painful. In addition, I developed atrial fibrillation and heart arrhythmia. Three CVs failed. The ablation is so far successful. I've been following a weight-loss regimen for six months, but my weight is up 40 lbs since I cannot exercise much, even with strict attention to weighing and measuring. My doctor said Buproprion is weight-neutral. However, the heart meds don't cause weight gain. It has to be the Bupropion. I am glad to know about others' weight problems. Does stopping the Bupropion reverse the weight gain and make it possible to lose weight again?
10 Dec 2014
Hi, the majority of antidepressants have this side effect. They tend to leave you with an increased appetite and reduced metabolic rate, so it is a double whammy. The only way to keep your weight stable is to keep within the government recommended daily calorie intake, or even reduce this by a couple of hundred calories, and take regular exercise... I know this is sometimes easier said than done, especially if you are feeling depressed, but this really is the only option to maintain a comfortable weight...
23 Jan 2015
I have taken numerous antidepressant recently my Dr put me on a thyroid medicine which he said is and additive to my anti depressant he said even with a healthy thyroid the medication could increase my mood along with keeping weight off not only do I feel so much better I have rapidly started taking off the weight my only change was the thyroid medication
15 Dec 2015
Yes exactly the same thing happens to me. My covers are all over the bed from tossing all night and I am exhausted daytime. I am a writer, so I peak at nnight. I am trying to be creative daytime. No way. Night is when ideas come out. So to regulate my day/night dysfunction my MD put me on Belsomra for sleep at night. It did nothing. I can't zip my jeans.
1 Jan 2016
I actually believe they are making a false claim that it may cause weight loss. I know a few girls who are on it and have gained at least 10-20lbs. I was on it only 3 months and gained 12lbs. I stopped it because gaining weight will only make me more depressed and hate myself. I think they should be sued because they are tricking people into believing it promotes weight-loss when it actually does the exact opposite. No one I know has ever lost weight from this medication.
26 Jan 2016
I have taken by buproprion Sr and xl. They've always helped me lose weight until I started getting one called buproprion xl HCL. Sometimes they don't mark it and you just have to guess. I started getting "the different kind" when I was about 37 or 38. It makes my butt immediately bigger and makes me gain weight. It is like prozac. It also makes me lethargic and I can no longer run. (I was in really good shape.) I have asked the pharmacy, the pharmaceutical company, my doctors over and over and over. I'm assuming they either don't know or are not allowed to tell me why I can't get the regular kind.
It is terribly frustrating.
28 Jan 2016
Yes it does make you gain weight. I had night terrors as well. I am a writer. I found that my thinking could not shut off at bedtime. I was restless and slept when this drug wore off. I was always more anxious too. Once I stopped it I felt normal. No more nightmares. My boyfriend noticed that I no longer talked in my sleep. Bad side effects.
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