... daily. Does this make it difficult for the body to regulate body temperature and or raise body temperature?
Buprenorphine - From comparisons ive heard about Im on a particularly high dose of suboxone 24ml?
- Posted:
- 2 Feb 2010 by brad hood
- Topics:
- suboxone, pain, buprenorphine
Added 3 Feb 2010:
If answer is yes -
which chemical or chemical interactions effect which organs in the process of doing so?
Answers (3)
3 Feb 2010
I'm not sure about other people, I'm only on 8 mg a day, which, I think is a low dose. I don't really understand what you're asking. The reason I'm answering is I have been thinking that something is wrong w/ my body's thermostat. I sweat WAY TOO MUCH. I'm hot when it's cold, cold when it's hot and some other weird things. I was wondering if that's what happening to you. Thanks. L.
7 Feb 2010
The average dose of Suboxone in America is approximately 8mg. 24mg is a very high dose. Buprenorphine acts on the Opioid receptors in the brain which can cause the side effects that Suboxone comes with such as body temperature increase/decrease and increased sweating. According to some studies Buprenorphine is approximately 15 to 25 times more potent than morphine sulfate. So I personally believe that Buprenorphine is approximately 15 times more potent than Morphine so if you multiply your dose by 15 you are taking approximately 375mg of Morphine theoretically. The organ that makes this possible is just the brain. There's many receptors in the brain so there's not a specific spot where it causes your body to change in temperature. The highest FDA approved dose is 32mg. I've personally been on 2mg and up to 32mg. Once you reach 24mg nothing really changes in the brain if you take more so the recommended highest dose of Buprenorphine is usually 24mg and that's when you reach the ceiling effect. I hope this helps. Good luck to you!
I think most certainly you are wrong about the variations in the different medications mentioned. From what i have been told suboxone last's longer than morphine though is not stronger.
As for your comment about the brain's receptors being responcible for the interaction''s in body temperature; well i had assumed brain receptors control nerve conduct and do not control temperature regulation. They may or may not play a part in distinguishing what the body should do ie, identifying temp, though do not actually increase or suppress temperature.
Besides its how the body is affected that im wanting to know. Once again id have though it would be organs of the body that do this.
please tell me if im wrong
I wasn't comparing the length of time that Buprenorphine compares to Morphine Sulfate. I've personally worked at a Vet Clinic and was a Vet Tech. The sheet that came with the Buprenorphine from the manufacture themselves (We would use it for pain management for dogs and cats) said that it's 15 to 25 times more potent than morphine. Remember that's coming from the Manufacture not me. As far as which one last longer, of course Buprenorphine last longer! It can last up to 11 days in you system according to the manufacture. That includes Suboxone. As far as how long morphine lasts, it's a lot less of course. If you do in fact look at the dosing for Pain management 24mg of Buprenorphine is equal to approximately 375mg of Morphine sulfate per day when treating pain and pain alone. Buprenorphine will last longer than the Morphine because it has a longer half life of course.
23 Mar 2012
I take IM Buprenex and I've experienced the same side effect — I tend to feel hot and sweat a lot, even when other people think it's chilly. I've taken my temperature — I suggest you do the same just to be sure. I don't know why it makes me feel hot but my temperature is normal.
When I first started taking bupe the side effects were hard to tolerate. I was able to cut down the side effects by dividing the dose up (i.e., taking smaller amounts more times a day).
24 mg (not mL) is a very high dose of buprenorphine (Suboxone is buprenorphine + naloxone, I'm assuming the 24 mg is the bupe dose?), even for addiction. I don't think I've ever heard of anyone taking more than 16 mg. (I take a total of about 1 mg/day, but that's by intramuscular injection). How big a habit did you have? You shouldn't be taking more than you can tolerate.
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I was asking in pursuit of an answer as to how suboxone effects the body's temperature regulation !!
Yes, with the use of suboxone i have found myself sweating more. I cannot identify with the cold when its hot bit with the axceptance of a quick cold flash that does not occur often. This does not happen in extreme heat either.