Has anyone experienced increased back and joint pain while taking Eliquis for A Fib?

Yes, I have been experiencing extreme lower back pain on Eliquis. I also tried Xarelto and had extreme and disabling back pain. Something seems to pool in my lower back. I can barely stand up or sit down.

i recently started taking Eliquis (about 3 weeks ago.). I noticed I was having stomach pains from it and I think that may be due to the fact that it was constipating me. Also before starting the drug I had off again on again mid back spasms which had gone away but have now returned and i'm pondering if the two issues are related to Eliquis. Also, I am feeling more pressure in the balls of my feet and some bone spurs which had been quiet are now awakening.

Yes I have been wondering why I have been having more pain. I haven’t thought of the connection with taking Eliquis.

I, too, have been aching all over, it seems, and in places I have never ached before, like the top of a foot and ankle. But besides the aches in my arm, wrists, and shoulder, have also had large, messy bowel actions that were horrible and caused incontinence when passing wind and also caused excoriation. I stopped Eliquis 3 days ago and put myself back on Aspirin 75 thrice weekly as prescribed by a cardiologist a few years ago, but at a time when AFib had not been diagnosed. Since stopping Eliquis bowels are back to normal and general aches and pains much reduced. My GP is not happy that I have stopped Eliquis and has asked that I make an appointment with one of the team to discuss. My AFib is paroxysmal, and as far as I am aware have had only one episode since being diagnosed at the end of February 2023.

I have been on Xarelto for four months and the fatigue, imbalance, and bleeding were extreme. The doctor changed the meds to Eliquis 2.5 mg and for two days there is less fatigue, better balance, and no bleeding. Perhaps after a few weeks, I can give a better evaluation.

Wow!! I had no idea this was a thing, I have all what you've talked about but I had not connected it to Eliquis! I've been on it for a year after having 3 pulmonary embolisms. Since then, which I have attributed to the PE, I've had really achy joints, shortness of breath (I'm currently waiting for some test results), etc all of it! So, has anyone been given an answer, or have a Dr that understands this?

I have been taking 5mg of Eliquis twice a day for one month and thought I was going crazy so tonight I started looking for others who may be experiencing what I experience with this drug. My nighttime dose causes me pain all over! It's not my imagination! I guess it's worse at night because I'm still and trying to sleep. In the day I feel it much less but oh my goodness at night!!! My feet, my ankles, my knees, my back sometimes, my shoulders and even my arms some days ACHE HORRIBLY!!! Some nights I don't sleep much and Advil, Tylenol and Aleve doesn't get rid of the pain. I suffer from migraines so my medicine for the headaches does help a bit more but has caffeine in it so it keeps me awake! I'm so frustrated! I got on this because of a DVT leading to a PE after a 20 minute procedure turned into a 2 hour procedure with the compression sleeves not being placed on my legs... I have 2 more months of this and I feel so awful at night I could cry...

pain in middle of back .painful

I have been on Eliquis for 6 months now and the pain in my leg and knee is so bad. Don’t know what will help it but I can’t hardly walk around now. It hurts all the way down my shin bone and knee hurting so bad also.

I have been on Eliquis for a year now. Whatever side effect this medicine has, I have it. I have been arguing with my doctors ever since being on it, with no avail. One doctor told me I had to live with all this, another doctor told me I was the only person to suffer these side effects. I also have joint pain, muscle pain and back pain. Before on Eliquis, I could do about anything. Now I can barely walk. I get breathless, I have weakness and headaches. I suppose it keeps me from having another stroke.

YES!! I have ached all over since starting Eliquis for AFib. I can hardly get out of bed in the mornings due to pain. My legs are weak and leg muscles sore.
My dr will not take me off it. I don't know what to do.

Yes! That's what led me to this site. Wanted to see if maybe someone else was experiencing the same. I've been having new joint pain/ache--- especially in my left hand and most pronounced when I wake up in the morning. Finger joints feel like they're burning! plus pressure/discomfort in my chest. I've been having some back & stomach pain as well, but I hadn't attributed it to the meds. I've been taking Eliquis (5mg x2) for almost 3mos now (DVT in thighs) and I'm supposed to take for 6mos, but I'm going to ask doc to wean me off. I just don't like the way it makes me feel.

I've only been on eliquis for about three months. (for afib). I am also experiencing joint pain. Mainly knees,
feet and less so in back. Knees are particularly bad. Legs seem weak too.

I'm so relieved to know there are others experiencing pain associated with Eliquis. I had a stroke almost 5 months ago at the age of 49 and the doctor in hospital suggested the new drug Eliquis. I was hesitant at first because of it's newness and no antidote factor. But after some convincing from the doctor I agreed. Now 5 months later I am in constant pain from morning to night which started at about 2 months in. I have read some stoke victims experience nerve pain that doesn't show up right away so I assumed that's what was happening and my neurologist said it might go away or I might have to live with it. After a few months of joint pain in my shoulder, down my arm, in both hips and feet I am wondering if this pain is from the medication. The doctor has now switched me to warfarin and I cannot wait to see if the pain subsides. I am going to hopefully come back to this feed and report a pain free life once again minus the Eliquis.

I took Eliquis for a DVT and I did notice that I had more knee and shoulder pain. I had asked my Dr about it and he said that it was a possible side effect but that I needed to continue the Eliquis since I had not had a good experience with Coumedin. I had to take the Eliquis for 6 months and after stopping it the joint pain did go away.