Vetrogen Ophthalmic Ointment

Company: Dechra

gentamicin sulfate

veterinary ophthalmic ointment

STERILE

ANADA # 200-273. Approved by FDA.

For use in dogs and cats.

Description

Gentamicin sulfate is a water soluble antibiotic of the aminoglycoside group active against a wide variety of pathogenic gram-negative and gram-positive bacteria.

Vetrogen^® ophthalmic ointment is a sterile ointment, each gram containing gentamicin sulfate (equivalent to 3 mg gentamicin) in a base of mineral oil and white petrolatum.

CHEMISTRY: Gentamicin sulfate is an aminoglycoside antibiotic mixture derived from Micromonospora purpurea of the Actinomycetes group. It is a powder, white to buff in color, readily soluble in water, and heat stable.

ACTION: Gentamicin sulfate, a broad spectrum antibiotic, is a highly effective topical treatment in primary and secondary bacterial infections of the eye and surrounding tissues. Gentamicin is bactericidal in vitro against a wide variety of gram-positive and gram-negative bacteria. Concentrations of gentamicin sulfate required to inhibit growth of gram-positive and gram-negative clinical and laboratory strains of bacteria tested were less than those of neomycin in most instances.^1,2 Gentamicin is active against most gram-negative bacteria including Pseudomonas aeruginosa, indole positive and negative Proteus species, Escherichia coli, Klebsiella sp. and Enterobacter sp. Gentamicin is also active against strains of gram-positive bacteria including Staphylococcus species and Streptococcus species.

Vetrogen Ophthalmic Ointment Indications

Vetrogen^® ophthalmic ointment is indicated for topical treatment of conjunctivitis caused by susceptible bacteria in dogs and cats.

Dosage and Administration

Apply approximately 1/2 inch strip of Vetrogen^® ophthalmic ointment to the affected eye(s) 2 to 4 times a day.

Precautions

Antibiotic susceptibility of infecting organisms should be determined prior to the use of these preparations. Prolonged use of topical antibiotics may give rise to overgrowth of nonsusceptible organisms such as fungi. Should this occur or if irritation or hypersensitivity to any component develops, discontinue use of the preparation and institute appropriate therapy. Ophthalmic ointments may retard corneal healing.

Vetrogen Ophthalmic Ointment Caution

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

How Supplied

Vetrogen^® veterinary ophthalmic ointment is supplied in 3.5 g (1/8 Oz) sterile tamper-proof tubes.

NDC 17033-044-38 3.5 gram tube

STORE BETWEEN 2°-30°C (36°-86°F).

MANUFACTURED FOR: Dechra Veterinary Products, Overland Park, KS 66211

1. Weinstein MJ, Leudemann GM, Oden EM, Wagman GH. Gentamicin, a new broad spectrum antibiotic complex. Antimicrob. Agents and Chemother. 1963:1-7.

2. Black J, et al. Pharmacology of Gentamicin: a new broad spectrum antibiotic. Antimicrob. Agents and Chemother. 1964:138-147.

I14438 DECHRA R10/07

#111

CPN: 14590530