Univax-Plus (Canada)

Bursal Disease Vaccine

Live Virus

STORE IN REFRIGERATOR AT 2° TO 7°C (35° TO 45°F).

Drinking Water Administration

Use only in chickens to be placed on premises with a history of infectious bursal disease.

Read Full Directions Below Carefully

Description

UNIVAX-PLUS is a live virus vaccine containing two strains of live bursal disease virus. The vaccine viruses have been demonstrated in controlled studies to provide protection against standard and variant strains of bursal disease virus. The vaccine viruses are grown in chicken embryos and cell culture, and are combined with stabilizing agents. The product is supplied as a lyophilized vaccine contained in vials sealed under vacuum.

Univax-Plus Indications

This vaccine is recommended for the vaccination of chickens or by drinking water at 2 weeks or older as an aid in preventing infectious bursal disease associated with infection by standard and variant strains of bursal disease virus.

Vaccination Programs

Many factors must be considered in determining the proper vaccination program for a particular farm or poultry operation. To be fully effective, the vaccine must be administered to healthy receptive chickens held in a proper environment under good management. In addition, the response may be modified by the age of the chickens and their immune status. Seldom does one vaccination under field conditions produce complete protection for all individuals in a given flock. The amount of protection required will vary with the type of operation and the degree of exposure that a flock is likely to encounter. For these reasons a program of periodic revaccination may be required.

Precautions

Only Vaccinate Healthy Chickens

Consult your poultry pathologist for further recommendations based on conditions existing in your area at any given time. Different vaccines should not be mixed for single application. The vaccination program for replacement pullets should not be started after chickens are 16 weeks of age.

Chickens should not be placed on contaminated premises. Exposure should be avoided immediately after vaccination, because it takes up to 10 days to develop resistance. All susceptible chickens on the same premises should be vaccinated at the same time. If this is not possible, then strict isolation and separate caretakers should be employed for non-vaccinated units. Efforts should be taken to reduce stress conditions at the time the vaccine is administered.

Rehydration Of The Vaccine

For Drinking Water Administration

2,500 DOSE VIALS AND 5,000 DOSE VIALS ARE FOR MASS ADMINISTRATION USE ONLY. DO NOT OPEN AND MIX THE VACCINE UNTIL READY TO BEGIN VACCINATION. USE VACCINE IMMEDIATELY AFTER MIXING.

1. Tear off the aluminum seal from the vial containing the dried vaccine.

2. Lift off the rubber stopper.

3. Pour a small amount of cool, clean non-chlorinated water (to which powdered milk has been added as directed below) into the vial of dried vaccine.

4. Put back the rubber stopper and shake vigorously until all material is dissolved.

5. The vaccine is now ready for drinking water use in accordance with directions below. For best results, be sure to follow directions carefully.

Drinking Water Administration

For Chickens 2 Weeks Of Age Or Older

1. Remove all medication, sanitizers, and disinfectants from the drinking water, preferably 72 hours before vaccinating and 24 hours following vaccination.

2. Provide enough watering space so that at least two-thirds of the chickens can drink at one time.

3. Scrub waterers thoroughly and rinse with fresh, clean water.

4. Withhold water for 2 hours before vaccinating to stimulate thirst.

5. Rehydrate the vaccine as directed above.

6. Drinking water for vaccination should be mixed with powdered milk to prevent inactivation from chlorine or other water additives and also to stabilize the vaccine virus. The powdered milk should be added to the water at the rate of 3 grams per 11 liters (1 heaped teaspoon per 2.5 Imp. gallons); or 90 grams per 300 liters (1 heaped cupful per 66 Imp. gallons).

7. Distribute the vaccine solution, as prepared above, among the waterers provided for the chickens. Avoid placing waterers in direct sunlight.

8. Provide no other drinking water until all the vaccine treated water has been consumed.

Univax-Plus Caution

For veterinary use only.

Use entire contents when first opened.

Do not vaccinate within 21 days before slaughter.

Store At 2° To 7°c (35° To 45°f).

Gentamicin is added as a preservative.

Burn container and all unused contents.

The capacity of this vaccine to produce satisfactory results depends on many factors including, but not limited to, conditions of storage and handling by the user, administration of the vaccine, health and responsiveness of individual animals and degree of field exposure. Therefore, directions for use should be followed carefully.

© 2006. Schering-Plough Animal Health Corp. All rights reserved.

Manufactured by: Schering-Plough Animal Health Corporation, Millsboro, Delaware 19966 U.S.A.

U.S. Veterinary License No.226

For: Schering-Plough Canada Inc., Pointe-Claire, Quebec H9R 1B4

^® Registered trademark of Schering-Plough Animal Health Corporation, used under license by Schering-Plough Canada Inc.

Nac No.