Tylosin Soluble Powder (Canada)

DIN 02324547

For swine, chickens and turkeys.

(tylosin tartrate)

VETERINARY USE ONLY

ANTIBIOTIC

Active Ingredient

Each 100 g jar contains: Tylosin 100 g (as tylosin tartrate 116 g)

Each 500 g jar contains: Tylosin 500 g (as tylosin tartrate 580 g).

Warnings

TREATED PIGS administered 1 g of tylosin per 4 L (250 mg/litre) of drinking water must not be slaughtered for use in food for at least 48 hours after the latest treatment of this drug.

TREATED CHICKENS administered 2 g of tylosin per 4 L (500 mg/litre) of drinking water must not be slaughtered for use in food for at least 24 hours after the latest treatment of this drug.

TREATED TURKEYS must not be slaughtered for use in food for at least 72 hours after the latest treatment of this drug.

Do not use in laying birds.

Direct contact with skin or mucous membranes during mixing may cause irritation. When handling this product, avoid inhalation, oral exposure and direct contact with skin or eyes.

Keep out of the reach of children.

NOTE: No withdrawal period is required when the drug is used as an aid in the treatment of porcine proliferative enteropathy (PPE), or ileitis, at 1 g tylosin per 12 L (83 mg/L) of drinking water, in pigs. No withdrawal period is required when the drug is used as an aid in the treatment of necrotic enteritis, at the dose range of 100 to 150 mg/litre, in broiler chickens.

Storage

Store between 2° and 35°C. Protect from light and humidity.

Tylosin Soluble Powder Indications

Swine:

(1) As an aid in the treatment of swine dysentery (bloody scours).

(2) As an aid in the treatment of porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis.

Chickens:

(1) As an aid in the treatment of chronic respiratory disease (CRD) in broilers and replacement flocks; or for the prevention of CRD at the time of vaccination or other stress.

(2) As an aid in the treatment of necrotic enteritis caused by Clostridium perfringens in broiler chickens.

Turkeys: As an aid in the treatment or for the prevention of infectious sinusitis.

Dosage and Administration

To reduce the development of antimicrobial resistance and maintain effectiveness, use this antibiotic prudently.

Mixing: 100 g - To assure thorough dissolving, place the Tylosin Soluble Powder (contents of this package) in a one-gallon or 5 L mixing container and add the water to the Tylosin Soluble Powder.

500 g - To assure thorough dissolving, place the Tylosin Soluble Powder (contents of this package) in a five gallon or 25 L mixing container and add the water to the Tylosin Soluble Powder.

Always add the water to the powder. Do not pour the powder into the water.

Note: 1 gram of tylosin is equivalent to 1.16 g Tylosin Soluble Powder (tylosin tartrate).

Pigs:

1. As an aid in the treatment of swine dysentery (bloody scours):

● Treat by way of the drinking water for 3 to 10 days at 1 g tylosin per 4 litres (250 mg/litre).

● 100 g - To make a solution of 1 gram tylosin per 4 litres (250 mg/litre), mix the contents of this package with 400 litres (approximately 100 U.S. gallons or 80 Imperial gallons) of water.
500 g - To make a solution of 1 gram tylosin per 4 litres (250 mg/litre), mix the contents of this package with 2000 litres (approximately 500 U.S. gallons or 400 Imperial gallons) of water.

2. As an aid in the treatment of porcine proliferative enteropathy (PPE) or ileitis associated with Lawsonia intracellularis:

● Treat by way of the drinking water for 14 days at 1 gram tylosin per 12 litres (83 mg/litre), or by way of drinking water for 7 days at 1 gram tylosin per 12 litres followed by 110 mg/kg tylosin phosphate premix in the feed for 7 days.

● 100 g - To make a solution of 1 gram tylosin per 12 litres (83 mg/litre), mix the contents of this package with 1200 litres (approximately 320 U.S. gallons or 265 Imperial gallons) of water.
500 g - To make a solution of 1 gram tylosin per 12 litres (83 mg/litre), mix the contents of this package with 6000 litres (approximately 1600 U.S. gallons or 1325 Imperial gallons) of water.

Chickens:

1. As an aid in the treatment of chronic respiratory disease (CRD) in broilers and replacement flocks; or for the prevention of CRD at the time of vaccination or other stress:

● Treat by way of the drinking water for 3 days at 2 grams tylosin per 4 litres (500 mg/litre); however, treatment may be administered for 1-5 days depending on the severity of infection.

● For the prevention of Chronic respiratory disease (CRD) at the time of vaccination or other stress: Chickens should be treated for the first 3 days of life. Repeat treatment for 1 day at 3 to 4 weeks of age, to coincide with vaccination or other stress.

● 100 g - To make a solution of 2 grams tylosin per 4 litres (500 mg/litre), mix the contents of this package with 200 litres (approximately 50 U.S. gallons or 40 Imperial gallons) of water.
500 g - To make a solution of 2 grams tylosin per 4 litres (500 mg/litre), mix the contents of this package with 1000 litres (approximately 250 U.S. gallons or 200 Imperial gallons) of water.

2. As an aid in the treatment of necrotic enteritis caused by Clostridium perfringens in broiler chickens:

● Treat by way of the drinking water for 5 days at not less than 100 mg/litre (0.4 gram per 4 litres) and not more than 150 mg/litre (0.6 gram per 4 litres) depending on the severity of the necrotic enteritis outbreak.

● 100 g - In order to provide not less than 100 mg/litre and not more than 150 mg/litre, make a solution of not less than 0.4 gram per 4 litres (mix contents of package with 1000 litres or approximately 264 U.S. gallons or 220 Imperial gallons) of water and not more than 0.6 gram per 4 litres (mix contents of package with 660 litres or approximately 175 U.S. gallons or 145 Imperial gallons) of water.
500 g - In order to provide not less than 100 mg/litre and not more than 150 mg/litre, make a solution of not less than 0.4 gram per 4 litres (mix contents of package with 5000 litres or approximately 1320 U.S gallons or 1100 Imperial gallons) of water and not more than 0.6 gram per 4 litres (mix contents of package with 3300 litres or approximately 875 U.S. gallons or 725 Imperial gallons) of water.

Turkeys:

As an aid in the treatment or for the prevention of infectious sinusitis:

● Treat by way of the drinking water for 3 days at 2 grams tylosin per 4 litres (500 mg/litre); however, treatment may be administered for 2-5 days depending on the severity of infection.

● For the prevention of infectious sinusitis, turkeys should be treated for the first 5 days of life. Repeat treatment for 2 days at 4 weeks of age.

● 100 g - To make a solution of 2 grams tylosin per 4 litres (500 mg/litre), mix the contents of this package with 200 litres (approximately 50 U.S. gallons or 40 Imperial gallons) of water.
500 g - To make a solution of 2 grams tylosin per 4 litres (500 mg/litre), mix the contents of this package with 1000 litres (approximately 250 U.S. gallons or 200 Imperial gallons) of water.

Note:

● In all species, if improvement is not observed within 5 days, the diagnosis should be reconfirmed.

● Medicated water should be the only source of drinking water during the treatment period.

● Prepare a fresh tylosin solution every 3 days. Solutions of this drug are stable for up to 3 days if kept refrigerated and protected from light.

● Administering the appropriate therapeutic dose is important to maximize performance and avoid the development of resistance to this medication.

Bio Agri Mix LP, PO Box 399, Mitchell, ON N0K 1N0

CONTAINS ANTIMICROBIAL

USE RESPONSIBLY

CPN: 1161034.2