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Capstar Tablets (11.4 mg) (Canada)

This treatment applies to the following species:
Company: Elanco

(nitenpyram)

TABLETS FOR DOGS AND CATS

DIN 02243436 (11.4 mg), 02243437 (57 mg)

Introduction

CAPSTAR (nitenpyram) Tablets have been developed for the oral treatment of flea infestations on cats and dogs. The active ingredient, nitenpyram, is a systemic flea adulticide which rapidly and completely eliminates adult fleas taking a blood meal from a treated animal. Nitenpyram interferes with normal nerve transmission in the fleas and leads to the death of these parasites.

Capstar Tablets (11.4 mg) Indication

CAPSTAR (nitenpyram) Tablets are indicated for the rapid elimination of fleas (Ctenocephalides felis) on dogs, cats, puppies and kittens four weeks of age and older.

Capstar Tablets (11.4 mg) Dosage And Administration

CAPSTAR Tablets are available in two concentrations of nitenpyram for convenient dosing: 11.4 mg per tablet for small dogs and cats and 57 mg per tablet for large dogs. The minimum recommended dosage is 1 mg of nitenpyram per kg of body weight. The product can be given directly into the mouth, or mixed with the pet’s favorite food according to the following schedule:

WEIGHT OF DOG OR CAT

DOSE (TABLETS)

1 to 11 kg

One small (11.4 mg) tablet per day, until fleas are no longer found on the host.

>11 to 57 kg

One large (57 mg) tablet per day, until fleas are no longer found on the host.

Dogs over 57 kg should receive the appropriate combination of tablets.

Flea detection can be achieved by examining the skin for signs of flea activity by parting the pet’s coat.

It is important to treat all dogs and cats in a household: fleas can reproduce on untreated dogs and cats and allow infestations to persist. Because immature fleas continue to develop into adult fleas for several weeks after the administration of CAPSTAR, repeated treatment may be necessary for optimal control of infestation.

Note: Effective long-term flea control demands an integrated approach. It is recommended to initiate administration of a flea treatment product with a longer duration of activity before treatment with CAPSTAR is discontinued.

Safety

CAPSTAR (nitenpyram) has a wide margin of safety in the intended species when used as per label directions. It can be safely administered to dogs, cats, puppies and kittens four weeks of age and older, pregnant or lactating females and breeding male and female dogs and cats.

CAPSTAR (nitenpyram) Tablets have been administered safely to cats and dogs in conjunction with other commonly used veterinary products including anthelmintics, antibiotics, corticosteroids, vaccines and shampoos.

There are no known contraindications to the use of this product in dogs and cats.

To report suspected adverse drug events or for technical assistance, contact Elanco at 1-800-265-5475.

Pharmacology

The active ingredient of CAPSTAR, nitenpyram, is a novel molecule belonging to the chemical class of neonicotinoid compounds, which bind with and inhibit insect specific nicotinic acetylcholine receptors; however, it does not inhibit acetylcholinesterase. It interferes with normal nerve transmission and leads to the death of the fleas.

Nitenpyram is very rapidly and almost completely absorbed from the gastrointestinal tract of cats and dogs; feeding does not influence absorption. On average, the maximum blood concentration is reached 1 hour (range: 15 to 90 minutes) after administration in both species, and the elimination half-life is about 3 hours in dogs and 7.5 hours in cats. More than 90% of the active ingredient is eliminated in the urine within one day in dogs and two days in cats, mainly as unchanged nitenpyram.

Nitenpyram starts working rapidly after dosing and kills >98% of the fleas on the pet within 6 hours; all adult fleas are eliminated 24 hours after a single treatment.

Capstar Tablets (11.4 mg) Caution

Do not administer this product to puppies or kittens less than four weeks of age.

Warnings

Keep this, and all drugs, out of the reach of children; if accidentally swallowed, call a physician.

Storage

Do not store above 25°C. Protect from humidity.

Presentation

CAPSTAR Tablets are available in two concentrations of nitenpyram for convenient dosing: 11.4 mg per tablet for small dogs and cats and 57 mg per tablet for large dogs. Each size is offered for sale in aluminum blisters containing six or sixty tablets per package. Not all package sizes may be marketed.

Elanco Canada Limited, 1919 Minnesota Court, Suite 401, Mississauga, Ontario L5N 0C9

Capstar, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

© 2023 Elanco or its affiliates.

04Jul2023

CPN: 1231038.9

ELANCO CANADA LIMITED
1919 MINNESOTA COURT, SUITE 401, MISSISSAUGA, ON, L5N 0C9
Customer Service:   800-265-5475
Fax:   519-821-7831
Website:   www.elanco.ca
Email:   elancocanadacustomerservice@elancoah.com
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