Bovi-Shield IBR

Manufacturer: Pfizer Animal Health

Bovine Rhinotracheitis Vaccine

Modified Live Virus

Product Description

Bovi-Shield IBR is for vaccination of healthy, nonpregnant cattle as an aid in preventing infectious bovine rhinotracheitis caused by infectious bovine rhinotracheitis (IBR) virus. Bovi-Shield IBR may be administered to calves nursing pregnant cows provided their dams were vaccinated, according to label directions, with any Bovi-Shield GOLD® FP^® or PregGuard ^® GOLD FP vaccine within the past 12 months. Bovi-Shield IBR is a freeze-dried preparation of a modified live virus (MLV) strain of the IBR virus, plus a sterile diluent used to rehydrate the freeze-dried vaccine. The viral antigen is propagated on an established cell line.

Disease Description

IBR virus is commonly associated with respiratory disease and/or reproductive failure in cattle. Infection is characterized by high temperature, excessive nasal discharge, conjunctivitis and ocular discharge, inflamed nose (“red nose”), increased rate of respiration, coughing, loss of appetite, and depression. Cattle infected during pregnancy may abort.

Safety And Efficacy

In safety studies with the IBR fraction of Bovi-Shield IBR, no adverse reactions to vaccination were observed.

Efficacy of the IBR fraction of Bovi-Shield IBR was demonstrated in a challenge-of-immunity study. Cattle vaccinated with the IBR fraction, followed by challenge with a disease-causing strain of IBR virus, had significantly fewer clinical signs than nonvaccinated control cattle.

Directions

General Directions: Vaccination of healthy, nonpregnant cattle is recommended. Aseptically rehydrate the freeze-dried vaccine with the sterile diluent provided, shake well, and administer 2 mL subcutaneously or intramuscularly. In accordance with Beef Quality Assurance guidelines, this product should be administered SC or IM in the neck region.

Primary Vaccination: Administer a single 2-mL dose to healthy cattle. To avoid possible maternal antibody interference with active immunization, calves vaccinated before the age of 6 months should be revaccinated after 6 months of age.

Revaccination: Annual revaccination with a single dose is recommended.

Good animal husbandry and herd health management practices should be employed.

Precautions

Do Not Use In Pregnant Cows (abortions Can Result). Do Not Use In Calves Nursing Pregnant Cows Unless Their Dams Were Vaccinated, According To Label Directions, With Any Bovi-shield Gold Fp Or Pregguard Gold Fp Vaccine Within The Past 12 Months.

Store at 2°-7°C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze.

Use entire contents when first opened.

Sterilized syringes and needles should be used to administer this vaccine. Do not sterilize with chemicals because traces of disinfectant may inactivate the vaccine.

Burn containers and all unused contents.

Do not vaccinate within 21 days before slaughter.

Contains gentamicin as preservative.

As with many vaccines, anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy.

This product has been shown to be efficacious in healthy animals. A protective immune response may not be elicited if animals are incubating an infectious disease, are malnourished

or parasitized, are stressed due to shipment or environmental conditions, are otherwise immunocompromised, or the vaccine is not administered in accordance with label directions.

Technical inquiries should be directed to Pfizer Animal Health Veterinary Services, (800) 366-5288 (USA), (800) 461-0917 (Canada).

For veterinary use only

U.S. Veterinary License No. 189

Pfizer Animal Health, Exton, PA 19341, USA, Div. of Pfizer Inc, NY, NY 10017

75-1315-00

Presentation

50 dose vial.

Nac No.

36900721