Aquaflor (Canada)

Company: Merck Animal Health

(florfenicol)

50% Medicated Premix for Salmon

Antibiotic

For Veterinary Use Only

DIN 02231742

Composition

Each kg of Aquaflor^® Premix contains 500 g (50%) of florfenicol in a palatable base.

Pharmacology

Aquaflor^®, a synthetic broad spectrum antibiotic which inhibits bacteria by interfering with protein synthesis, is active in vitro against a number of important bacterial pathogens of salmon including: Aeromonas salmonicida, Vibrio salmonicida, Vibrio anguillarum and Yersinia ruckeri. Aquaflor^® is rapidly absorbed from the intestine of salmon when administered in medicated feed. It is excreted mainly in the urine and bile.

Aquaflor Indications

For the treatment of furunculosis caused by susceptible strains of Aeromonas salmonicida in salmon.

Warnings: Treated fish must not be harvested for use in food, or released as stocker fish, for at least 12 days after the latest treatment with this drug. Do not use in fish maintained at water temperatures below 5°C. Avoid inhalation of dust and contact with skin and eyes. Wear protective clothing (mask and gloves). Wash hands after handling. Keep this and all medication out of the reach of children.

Dosage and Administration

Mix into non-medicated feed prior to pelleting, or use to surface coat pelleted feed. Feed mixture should deliver 10 mg florfenicol/kg body weight. Administer for 10 consecutive days. See table for recommended Aquaflor^® feed inclusion rate.

Recommended Aquaflor^® Inclusion Rates for Preparation of Medicated Feed

For surface coating at the farm premises: Using an appropriate mixer, mix thoroughly the contents of one 25 kg bag of non-medicated fish feed with the amount of Aquaflor^® calculated based on feeding rate (for example, at a feeding rate of 1% of body weight, 50 grams of Aquaflor^® should be added per 25 kg bag of feed). Then add approximately 1 litre of an edible fish or vegetable oil and mix together for several minutes more to ensure uniform coating.

Storage

Store in a dry place between 2°C and 30°C. Use premix within 12 months of opening pouch. Use medicated feed not more than 6 months after manufacture. Keep separate from other feeds.

How Supplied

Aquaflor^® is provided in individual 2 kg sealed laminated foil pouches.

Intervet Canada Corp., subsidiary of Merck & Co., Inc., 16750, route Transcanadienne, Kirkland, QC H9H 4M7

1 866 683-7838

^® Registered trademark of Intervet Canada Corp.

CPN: 1208000.6