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Veozah

Pronunciation: vee-O-zah
Generic name:  fezolinetant
Dosage form: tablets, for oral use
Drug class: Miscellaneous central nervous system agents

Medically reviewed by Judith Stewart, BPharm. Last updated on Mar 26, 2024.

What is Veozah?

Veozah is a nonhormonal prescription medicine used to reduce moderate to severe vasomotor symptoms (hot flashes and night sweats) due to menopause. 

Before a woman enters menopause, a balance exists between the estrogen hormones and a brain chemical called neurokinin B (NKB), that works to regulate the body’s temperature. During menopause, estrogen levels decline and this balance is disrupted, leading to vasomotor symptoms.

Veozah contains a drug called fezolinetant. Fezolinetant is a neurokinin 3 (NK3) receptor antagonist that works to reduce the frequency and intensity of hot flashes by restoring the balance between estrogen and NKB by blocking NKB in the temperature control center of the brain.

What is Veozah used to treat?

Veozah is used for the treatment of moderate to severe vasomotor symptoms due to menopause. 

Vasomotor symptoms are intense feelings of heat ("hot flashes" or "hot flushes"), night sweats, and feelings of warmth in the face, neck, and chest that can occur frequently in women transitioning through menopause.

Menopause is the natural change in a woman’s life when her period stops, usually between the ages 45 and 55. Up to 80% of menopausal women are thought to experience hot flashes, which can include periods of sweating, flushing and chills lasting for several minutes.

Who should not use Veozah?

Do not use Veozah if you:

Veozah pregnancy and breastfeeding warnings (more detail)

What should I tell my healthcare provider before taking Veozah?

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

Pregnancy

There are no data for Veozah use during pregnancy.

Breastfeeding

There are no data for Veozah use during breastfeeding.

What other drugs will affect Veozah?

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Veozah may affect the way other medicines work, and vice versa. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine.

Especially tell your healthcare provider if you are taking certain medicines called CYP1A2 inhibitors.

CYP1A2 inhibitors include:

Veozah drug interactions (more detail)

How should I take Veozah?

Dosing information

Usual Adult Dose for Vasomotor Symptoms Due to Menopause

45 mg orally once daily

Use:
- treatment of moderate to severe vasomotor symptoms due to menopause.

Detailed Veozah dosage information

Veozah side effects

Veozah can cause serious side effects, including:

Call your healthcare provider right away if you have the following signs and symptoms of liver problems:

Common Veozah side effects include:

Tell your healthcare provider if you have any side effect that bothers you or does not go away.

These are not all the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Veozah side effects (more detail)

How should I store Veozah tablets?

Keep all medicines out of the reach of children and pets.

General information about the safe and effective use of Veozah.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms you have. It may harm them.

This page summarizes the most important information. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information that is written for healthcare professionals.

What are the ingredients in Veozah?

Active ingredient: fezolinetant
Inactive ingredients: ferric oxide, hydroxypropyl cellulose, hypromellose, low-substituted hydroxypropyl cellulose, magnesium stearate, mannitol, microcrystalline cellulose, polyethylene glycol, talc, and titanium dioxide

Popular FAQ

No, Veozah is not a hormone treatment. Veozah works by helping to restore the balance between estrogens and neurokinin B (NKB), a brain chemical. Veozah blocks NKB in the temperature control center to reduce the number and intensity of hot flashes and night sweats.

There is no evidence that Veozah, a nonhormonal medicine used for menopausal vasomotor symptoms (hot flashes and night sweats) will help with weight loss. But for some people it may be a good alternative to SSRI antidepressants that could cause weight gain.

One week after starting treatment, Veozah taken once per day may help to reduce the number and severity of your hot flashes and night sweats associated with menopause. This effect has shown to be persistent, lasting through at least one year.

Do not use Veozah with caffeine as this combination may increase the amount of medicine in your blood and cause side effects. Caffeine is found in coffee, chocolate, tea, colas, energy drinks, and some medicines. Caffeine and hot beverages can also be a trigger for hot flashes during menopause.

Veozah helps to reduce the number and severity of menopausal hot flashes and night sweats by blocking a chemical in your brain called neurokinin B (NKB). Veozah is a nonhormonal treatment that works by restoring the balance between estrogens and NKB, which can be a trigger for vasomotor symptoms.

References

  1. Veozah Product Label

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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