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Active substance: LYMECYCLINE

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Lymecycline 408mg
Capsules, hard
Read all of this leaflet carefully before you
start taking this medicine because it contains
important information for you.
• Keep this leaflet. You may need to read it again.
•   f you have any further questions, ask your
doctor or pharmacist.
•   his medicine has been prescribed for you only.
Do not pass it on to others. It may harm them,
even if their signs of illness are the same as
•   f you get any side effects, talk to your doctor
or pharmacist. This includes any possible side
effects not listed in this leaflet. See section 4.
•   he full name of this medicine is Lymecycline
408mg Capsules, hard but within the leaflet it
will be referred to as Lymecycline capsules.

What is in this leaflet
1  hat Lymecycline capsules are and what
they are used for
2 What you need to know before you take
3 How to take
4 Possible side effects
5 How to store
6  ontents of the pack and other
1  hat Lymecycline capsules are and what

they are used for

Lymecycline capsules belongs to a group of
medicines called tetracycline antibiotics.
It is used to treat acne; which appears as blackheads
and whiteheads which people often refer to as
pimples or spots.
This medicine can also be used to treat other
infections such as
• Acute sinusitis
• Bronchitis
• Infections in the abdomen
• Some types of eye infections called trachoma
• Soft tissue infections.

2 What you need to know before you take
Do not take Lymecycline capsules if you:

• are allergic to lymecycline, any other tetracyclines or

any of the other ingredients of this medicine (listed
in section 6)
•  ave ever had kidney disease
• are a child under the age of 12 years

• are pregnant or breastfeeding.

Warnings and precautions

Talk to your doctor or pharmacist before taking
Lymecycline capsules if you:
•  ave had liver problems
•  ave had kidney problems
•  uffer from systemic lupus erythematosus (an
allergic condition that causes joint pain, skin rashes
or fever)
•  uffer from Myasthenia Gravis (a disease that
weakens the muscles).
You should avoid direct exposure to sunlight or
artificial sunlight from sunbeds. If you experience skin
discomfort then stop taking this medicine and seek
advice from your doctor.

Continued top of next column

Children and adolescents

Lymecycline capsules is not recommended for use
in children under 12 years of age as it can cause
permanent discolouration of tooth enamel and affect
bone development.

Other medicines and Lymecycline capsules

Tell your doctor or pharmacist if you are taking, have
recently taken or might take any other medicines.
Do not take the following medicines at the same time
as Lymecycline capsules, take them at least two hours
before Lymecycline capsules or two hours after:
• indigestion remedies

• ulcer healing drugs

• quinapril (for high blood pressure)

• supplements containing calcium, aluminium,

magnesium, zinc or iron.
Tell your doctor if you are taking any of the following:
•  ral retinoids (to treat acne)
• anticoagulants (to stop the blood clotting)

• diuretics (used to treat kidney disease, heart disease

or high blood pressure)
• oral contraceptives (the pill). Lymecycline capsules

may make the oral contraceptive pill less effective.
You should use additional contraceptive precautions
whilst taking Lymecycline capsules
• medicines for epilepsy including barbiturates e.g.

phenobarbitone, phenytoin and carbamazepine
• methoxyflurane (an anaesthetic).

Lymecycline capsules with food and drink

Absorption of Lymecycline capsules is not affected by
moderate amounts of milk (e.g. a glass). Lymecycline
capsules should always be taken with a glass of water.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may
be pregnant or are planning to have a baby, ask your
doctor or pharmacist for advice before taking this
Lymecycline capsules must not be taken if you are
pregnant or breast feeding.
Use of medicines such as Lymecycline capsules may
affect the proper growth of developing teeth and lead
to permanent discolouration.

Driving and using machines

No studies on the effects on the ability to drive and
use machines have been performed.

3 How to take
Always take this medicine exactly as your doctor or
pharmacist has told you. Check with your doctor or
pharmacist if you are not sure.

Adults and children over 12 years
The normal dose is one Lymecycline capsule once a
day, preferably in the morning. Lymecycline capsules
should always be taken with a glass of water.
How long you will have to take Lymecycline capsules
for will depend on how quickly your condition
improves. For acne, this will normally be at least 8
For other infections, the usual dosage is one
Lymecycline capsule twice a day. Your doctor may
recommend a lower or higher dose depending on the
severity and type of infection. Ask your doctor if you
are unsure.
Lymecycline capsules should always be taken with a
glass of water.
Continued over page

Use in children under 12 years
Lymecycline capsules is not recommended for use
in children under 12 years of age as it can cause
permanent discolouration of tooth enamel and affect
bone development.

If you take more Lymecycline capsules than
you should

If you (or someone else) takes too many capsules, or
you think a child may have swallowed any contact
your nearest hospital casualty department or tell your
doctor immediately.

If you forget to take Lymecycline capsules

Do not take a double dose to make up for a forgotten
dose. If you forget to take a dose take it as soon as you
remember it and then take the next dose at the right

If you stop taking Lymecycline capsules

Acne responds slowly to antibiotics. It is important that
you take all the Lymecycline capsules that your doctor
has prescribed for you. If you stop taking Lymecycline
capsules too soon, your acne or infection could get
worse or come back.
If you have any further questions on the use of this
medicine, ask your doctor or pharmacist.

4 Possible side effects
Like all medicines, this medicine can cause side effects,
although not everybody gets them.
If you experience any of the following serious side
effects, stop taking your capsules and tell your
doctor immediately or go to the nearest hospital
accident and emergency department.
Unknown frequency of occurrence (frequency cannot
be estimated from the available data):
•  erious allergic reaction which causes swelling of the
face, tongue and throat that can cause great difficulty
in breathing.
•  erious illness with severe peeling and swelling of the
skin, blistering of the skin, mouth, eyes genitals and
fever. Skin rash with pink-red blotches especially on
palms of hands or soles of feet which may blister.
Lymecycline capsules may also cause the following
side effects.
Common side effects (occur in less than 1 in 10
•  ausea (feeling sick)
•  bdominal pain
• diarrhoea
• headache.
Unknown frequency of occurrence (frequency cannot
be estimated from the available data)
•  isturbances of eyesight
• dizziness
•  omiting (being sick)
•  ellowing of the skin or eyes (jaundice)
• ncreased sensitivity of the skin to sunlight
• ncreased pressure in the brain
•  hanges in the number or type of certain blood cells
•  ain in the upper part of the abdomen
•  hanges in some blood tests (tests of liver function)
• fever
• tchiness, skin rash or hives
• nflammation of the intestine.

Reporting of side effects

If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side
effects directly via the Yellow Card Scheme at: www.
By reporting side effects you can help provide more
information on the safety of this medicine.

5 How to store
Keep this medicine out of the sight and reach of
Do not use this medicine after the expiry date which
is stated on the carton or blister after EXP. The expiry
date refers to the last day of that month.
Store below 25°C.
Store in the original package in order to protect from
Do not throw away any medicines via wastewater or
household waste. Ask your pharmacist how to throw
away medicines you no longer use. These measures
will help protect the environment.

6  ontents of the pack and other


What Lymecycline capsules contains

• The active substance is lymecycline. Each capsule
contains 408mg of lymecycline equivalent to 300mg
tetracycline base.
• The other ingredients are colloidal hydrated silica,
magnesium stearate, capsule body: titanium dioxide
(E171), gelatine, capsule cap: indigo carmine FD&C
Blue (E132), black iron oxide (E172), titanium dioxide
(E171), yellow iron oxide (E172), gelatine.

What Lymecycline capsules looks like and
contents of the pack
Hard gelatin capsule, blue cap and white body.
Pack sizes:
28 and 56 capsules in Al/Al blister strip.
Marketing Authorisation Holder
Actavis Group PTC ehf.
Reykjavíkurvegi 76-78
220 Hafnarfjörður
Actavis hf.
Reykjavikurvegur 76-78
IS-220 Hafnarfjörður
This leaflet was last revised in April 2015

If you would like a
leaflet with larger
text, please contact
01271 385257.

The following side effects may occur during treatment
with the class of medicines to which Lymecycline
capsules belongs (the tetracyclines):
• nflammation or ulceration of the gullet, causing pain
or difficulty swallowing or painful heartburn
•  ifficulty in swallowing
• nflammation of the pancreas
• iver damage
•  eeth discolouration
• nflammation or soreness of the tongue, mouth,
cheeks, gums or lips
•  oreness or itching of the genital area
•  east infection around the anus or genitals
• nfection of the colon
•  ermanent visual loss.
Continued top of next column

Actavis, Barnstaple, EX32 8NS, UK

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.