Trileptal

Pronunciation

Generic Name: oxcarbazepine (ox kar BAY zeh peen)
Brand Names: Oxtellar XR, Trileptal

What is Trileptal?

Trileptal (oxcarbazepine) is in a group of drugs called anticonvulsants, or antiepileptic drugs. It works by decreasing nerve impulses that cause seizures.

Trileptal is used to treat partial seizures in adults and children who are at least 2 years old.

Trileptal may also be used for purposes not listed in this medication guide.

Important information

Trileptal is used to treat partial seizures in adults and children who are at least 2 years old.

Trileptal can reduce the sodium in your body to dangerously low levels, which can cause a life-threatening electrolyte imbalance. Contact your doctor right away if you have headache, problems with thinking or memory, weakness, loss of appetite, feeling unsteady, confusion, hallucinations, fainting, shallow breathing, and/or increased or more severe seizures.

Slideshow: Flashback: FDA Drug Approvals 2013

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Before taking this medicine

You should not take Trileptal if you are allergic to oxcarbazepine.

To make sure you can safely take Trileptal, tell your doctor if you have:

  • liver disease;

  • kidney disease; or

  • if you are allergic to a similar medicine called carbamazepine (Carbatrol, Tegretol).

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Trileptal. Your family or other caregivers should also be alert to changes in your mood or symptoms.

FDA pregnancy category C. Do not start or stop taking Trileptal during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking Trileptal for seizures.

See also: Pregnancy and breastfeeding warnings (in more detail)

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Trileptal on the baby.

Trileptal can make birth control pills less effective. Ask your doctor about using a non hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking Trileptal.

Oxcarbazepine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking Trileptal.

Do not give this medication to a child younger than 2 years old.

How should I take Trileptal?

Take Trileptal exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Trileptal with a full glass of water.

Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, use the oral dosing syringe provided with this medicine. If you did not receive an oral syringe with your medication, ask your pharmacist for one.

Give the oral liquid directly from the oral syringe, or mix the medicine with a small glass of water. After using the syringe, rinse it with water and allow it to air dry.

Use Trileptal regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not stop using Trileptal suddenly, even if you feel fine. Stopping suddenly may cause increased seizures.

While using Trileptal, you may need blood tests at your doctor's office. Visit your doctor regularly.

Wear a medical alert tag or carry an ID card stating that you take Trileptal. Any medical care provider who treats you should know that you are using this medicine.

Seizures are often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Store Trileptal at room temperature away from moisture and heat. Throw away any unused liquid 7 weeks after opening the bottle.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Trileptal may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of Trileptal. Alcohol may also increase the risk of seizures.

Trileptal side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Trileptal: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Trileptal can reduce the sodium in your body to dangerously low levels, which can cause a life-threatening electrolyte imbalance. Contact your doctor right away if you have headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, confusion, hallucinations, fainting, shallow breathing, and/or increased or more severe seizures.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • increased seizures;

  • swollen glands, fever, chills, body aches, flu symptoms, sores in your mouth and throat;

  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  • severe tingling, numbness, pain, muscle weakness;

  • urinating less than usual or not at all;

  • chest pain, dry cough, wheezing, feeling short of breath;

  • upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common Trileptal side effects may include:

  • headache, mental slowness, trouble concentrating;

  • problems with speech, balance, or walking;

  • dizziness, drowsiness, tired feeling;

  • mild nausea, vomiting, upset stomach, diarrhea;

  • blurred vision, double vision;

  • tremors or shaking; or

  • skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Trileptal?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Trileptal, especially:

  • carbamazepine;

  • cyclosporine;

  • felodipine;

  • phenobarbital;

  • phenytoin;

  • valproic acid; or

  • verapamil.

This list is not complete and there are many other drugs that can interact with Trileptal. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

This list is not complete and many other drugs can interact with Trileptal. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

  • Your pharmacist has information about Trileptal.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Trileptal only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 10.03. Revision Date: 2013-03-05, 11:52:14 AM.

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