Z-Tuss AC Side Effects

Generic name: chlorpheniramine / codeine

Note: This document contains side effect information about chlorpheniramine / codeine. Some of the dosage forms listed on this page may not apply to the brand name Z-Tuss AC.

Some side effects of Z-Tuss AC may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to chlorpheniramine / codeine: oral liquid, oral suspension, oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking chlorpheniramine / codeine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using chlorpheniramine and codeine and call your doctor at once if you have a serious side effect such as:

• confusion, mood changes, hallucinations, unusual thoughts or behavior;

• severe dizziness or drowsiness, feeling like you might pass out;

• severe nervousness, fast or uneven heart rate, tremor, seizure (convulsions);

• pain or numbness in the arms or legs;

• severe stomach cramps or constipation;

• weak or shallow breathing;

• easy bruising or bleeding, unusual weakness; or

• urinating less than usual or not at all.

Less serious side effects of chlorpheniramine / codeine may include:

• dizziness, drowsiness, tired feeling;

• dry mouth, nose, or throat;

• blurred vision;

• nausea, vomiting, constipation; or

• sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to chlorpheniramine / codeine: oral liquid, oral suspension, oral suspension extended release, oral tablet

Cardiovascular

Cardiovascular side effects have included fast, slow, or pounding heartbeat, hypertension, hypotension, orthostatic hypotension, palpitation, shock-like state, and syncope.

Nervous system

Nervous system side effects have included blurred, double, or other visual disturbances; confusion; dizziness; depression; drowsiness and sedation; headache; euphoria; facial dyskinesia; false sense of well-being; feeling faint, lightheadedness, general feeling of discomfort or illness; nervousness, agitation and restlessness; minimal sedation; somnolence; insomnia, dyskinesia, irritability, and tremor.

Gastrointestinal

Gastrointestinal side effects have included abdominal distension, abdominal pain, acute pancreatitis, constipation, diarrhea, dry mouth, dyspepsia, epigastric distress, loss of appetite, nausea, vomiting, and decreased gastric motility with increased likelihood of esophageal reflux.

Respiratory

Respiratory side effects have included dryness of pharynx and respiratory passages, laryngismus, nasal stuffiness, wheezing or troubled breathing, and respiratory depression.

Endocrine

Endocrine side effects have included changes in glucose utilization, decreased lactation, early menses, glycosuria, gynecomastia, hypoglycemia, increased appetite, increased libido, and pheochromocytoma stimulation.

Dermatologic

Dermatologic side effects have included dermatitis, excessive perspiration, urticaria, erythema, pruritus, and rash.

Hypersensitivity

Hypersensitivity side effects have included allergic laryngospasm, atelectasis, bronchospastic allergic reaction, hives, itching, and swelling of face.

Ocular

Ocular side effects have included blurred vision, diplopia, hypermetropia, lacrimation increased, mydriasis, and photophobia.

General

General side effects have included asthenia, feeling of relaxation, redness or flushing of the face, and unusual tiredness or weakness.

Other

Other side effects have included labyrinthitis, tinnitus, and vertigo.

Immunologic

Immunologic side effects have included drug fever.

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