Vitamin B6 Side Effects

Generic Name: pyridoxine

Note: This document contains side effect information about pyridoxine. Some of the dosage forms listed on this page may not apply to the brand name Vitamin B6.

Some side effects of Vitamin B6 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release

Along with its needed effects, pyridoxine (the active ingredient contained in Vitamin B6) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking pyridoxine:

With large doses
  • Clumsiness
  • numbness of hands or feet

For Healthcare Professionals

Applies to pyridoxine: compounding powder, injectable solution, oral tablet

Nervous system

The profound sensory loss following treatment with high doses of parenteral pyridoxine (the active ingredient contained in Vitamin B6) may not be reversible.

Nervous system side effects have included sensory neuropathy with axonal degeneration. The adverse neurologic side effects have been reported following a single large dose (10 g) administered intravenously. It may rarely occur following chronic administration of lower doses. Peripheral sensory neuropathy has also been reported.

Hypersensitivity

Hypersensitivity side effects have been reported rarely.

Dermatologic

Dermatologic side effects have included allergic contact dermatitis. Photosensitivity has been confirmed in a female patient taking pyridoxine (the active ingredient contained in Vitamin B6) 100 mg orally daily.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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