Vitamin B1 Side Effects

Generic name: thiamine

Note: This document contains side effect information about thiamine. Some of the dosage forms listed on this page may not apply to the brand name Vitamin B1.

Some side effects of Vitamin B1 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to thiamine: injectable solution, oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking thiamine (the active ingredient contained in Vitamin B1) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• blue colored lips;

• chest pain, feeling short of breath;

• black, bloody, or tarry stools; or

• coughing up blood or vomit that looks like coffee grounds.

Less serious side effects of thiamine may include:

• nausea, tight feeling in your throat;

• sweating, feeling warm;

• mild rash or itching;

• feeling restless; or

• tenderness or a hard lump where a thiamine injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to thiamine: compounding powder, injectable solution, oral tablet

Local

Local side effects have included tenderness and induration at the injection site following intramuscular use.

Hypersensitivity

Hypersensitivity side effects have included a feeling of warmth, pruritus, urticaria, weakness, sweating, nausea, restlessness, tightness of the throat, angioneurotic edema, cyanosis, pulmonary edema, and hemorrhage into the gastrointestinal tract. Anaphylaxis has been reported, especially after repeated injection. Collapse and death have also been reported.

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