Valstar Side Effects

Generic Name: valrubicin

Note: This document contains side effect information about valrubicin. Some of the dosage forms listed on this page may not apply to the brand name Valstar.

Some side effects of Valstar may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to valrubicin: intravesical solution

Along with its needed effects, valrubicin (the active ingredient contained in Valstar) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of valrubicin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Blood in urine
  • loss of bladder control
  • painful or difficult urination
  • red color in urine
  • strong urge to urinate
  • unusually frequent urination
Less common
  • Increased urination at night
  • local burning sensation
Rare
  • Frequent urge to defecate
  • itching
  • loss of sense of taste

For Healthcare Professionals

Applies to valrubicin: irrigation solution

Local

Local adverse reactions associated with valrubicin (the active ingredient contained in Valstar) usually occurred during or shortly after instillate and resolve within one to seven days after the instillation is removed from the bladder.

Very common (10% or more): Any local bladder symptom (88%)
Common (1% to 10%): Procedure related local burning symptoms

Genitourinary

Very common (10% or more): Urinary frequency (61%), urinary urgency (57%), dysuria (56%), bladder spasm (31%), hematuria (29%), bladder pain (28%), urinary incontinence (22%), urinary tract infection (15%), cystitis (15%)
Common (1% to 10%): Nocturia, urinary retention, microscopic hematuria, urethral pain, pelvic pain, gross hematuria
Frequency not reported: Poor urine flow, urethritis

General

The most common side effects were local bladder symptoms, including urinary frequency, urinary urgency, and dysuria.

Gastrointestinal

Common (1% to 10%): Abdominal pain, nausea, diarrhea, vomiting, flatulence
Frequency not reported: Tenesmus

Nervous system

Common (1% to 10%): Headache, dizziness
Frequency not reported: Taste loss

Dermatologic

Common (1% to 10%): Rash
Frequency not reported: Pruritus, local skin irritation

Cardiovascular

Common (1% to 10%): Vasodilation

Hematologic

Common (1% to 10%): Anemia

Metabolic

Common (1% to 10%): Hyperglycemia, peripheral edema
Frequency not reported: Nonprotein nitrogen increased

Musculoskeletal

Common (1% to 10%): Back pain, myalgia

Respiratory

Common (1% to 10%): Pneumonia

Other

Common (1% to 10%): Asthenia, malaise, chest pain, fever

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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