Valstar Side Effects
Generic Name: valrubicin
Note: This page contains side effects data for the generic drug valrubicin. It is possible that some of the dosage forms included below may not apply to the brand name Valstar.
Common side effects of Valstar include: cystitis, bladder spasm, urinary urgency, bladder pain, dysuria, urinary incontinence, urinary frequency, and hematuria. Other side effects include: nocturia. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to valrubicin: intravesical solution
As well as its needed effects, valrubicin (the active ingredient contained in Valstar) may cause unwanted side effects that require medical attention.
Some valrubicin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:More common:
- Blood in urine
- loss of bladder control
- painful or difficult urination
- red color in urine
- strong urge to urinate
- unusually frequent urination
- Increased urination at night
- local burning sensation
- Frequent urge to defecate
- loss of sense of taste
For Healthcare Professionals
Applies to valrubicin: irrigation solution
Local adverse reactions associated with valrubicin (the active ingredient contained in Valstar) usually occurred during or shortly after instillate and resolve within one to seven days after the instillation is removed from the bladder.[Ref]
Very common (10% or more): Any local bladder symptom (88%)
Common (1% to 10%): Procedure related local burning symptoms[Ref]
Very common (10% or more): Urinary frequency (61%), urinary urgency (57%), dysuria (56%), bladder spasm (31%), hematuria (29%), bladder pain (28%), urinary incontinence (22%), urinary tract infection (15%), cystitis (15%)
Common (1% to 10%): Nocturia, urinary retention, microscopic hematuria, urethral pain, pelvic pain, gross hematuria
Frequency not reported: Poor urine flow, urethritis[Ref]
The most common side effects were local bladder symptoms, including urinary frequency, urinary urgency, and dysuria.[Ref]
Common (1% to 10%): Abdominal pain, nausea, diarrhea, vomiting, flatulence
Frequency not reported: Tenesmus[Ref]
Common (1% to 10%): Headache, dizziness
Frequency not reported: Taste loss[Ref]
Common (1% to 10%): Rash
Frequency not reported: Pruritus, local skin irritation[Ref]
Common (1% to 10%): Vasodilation[Ref]
Common (1% to 10%): Anemia[Ref]
Common (1% to 10%): Hyperglycemia, peripheral edema
Frequency not reported: Nonprotein nitrogen increased[Ref]
Common (1% to 10%): Back pain, myalgia[Ref]
Common (1% to 10%): Pneumonia[Ref]
Common (1% to 10%): Asthenia, malaise, chest pain, fever
1. "Product Information. Valstar (valrubicin)." Medeva Pharmaceuticals, Rochester, NY.
It is possible that some side effects of Valstar may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
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